The fission yeast Rpb4 subunit of RNA polymerase II plays a specialized role in cell separation

Molecular Genetics and Genomics

Volumn 276, Issue 6, 2006, Pages 545-554

  Sharma, Nimisha ^a,b   Marguerat, Samuel ^b   Mehta, Surbhi ^a   Watt, Stephen ^b   Bähler, Jürg ^b  

^a GURU GOBIND SINGH INDRAPRASTHA UNIVERSITY   (India)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

Cell division; Growth; S. pombe; Transcription

Indexed keywords

CYCLIN DEPENDENT KINASE 7; CYCLIN DEPENDENT KINASE ACTIVATING KINASE; MUTANT PROTEIN; RNA POLYMERASE II; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RPB4; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE REGULATION; CELL DIVISION; CELL GROWTH; CELL SEPARATION; CELL SURVIVAL; CONTROLLED STUDY; GENE EXPRESSION; GENETIC TRANSCRIPTION; MICROARRAY ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; STRESS; YEAST;

CELL DIVISION; GENE EXPRESSION REGULATION, FUNGAL; MICROARRAY ANALYSIS; MICROSCOPY, FLUORESCENCE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA POLYMERASE II; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS;

MAMMALIA; METAZOA; SACCHAROMYCETALES; SCHIZOSACCHAROMYCES POMBE;

EID: 33750624797     PISSN: 16174615     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00438-006-0161-5     Document Type: Article

References (46)

1. Alonso-Nunez ML, An H, Martin-Cuadrado AB, Mehta S, Petit C, Sipiczki M, del Rey F, Gould KL, de Aldana CR (2005) Ace2p controls the expression of genes required for cell separation in Schizosaccharomyces pombe. Mol Biol Cell 16:2003-2017
2. Armache K-J, Mitterweger S, Meinhart A, Cramer P (2005) Structures of complete RNA polymerase II and its subcomplex Rpb4/7. J Biol Chem 280:7131-7134
3. Bähler J (2005) A transcriptional pathway for cell separation in fission yeast. Cell Cycle 4:39-41
4. Bähler J, Wu J-Q, Longtine MS, Shah NG, McKenzie A III, Steever AB, Wach A, Philippsen P, Pringle JR (1998) Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe. Yeast 14:943-951
5. Basi G, Schmid E, Maundrell K (1993) TATA box mutations in the Schizosaccharomyces pombe nmt1 promoter affect transcription efficiency but not the transcription start point or thiamine repressibility. Gene 123:131-136
6. Bushnell DA, Kornberg RD (2003) Complete, 12-subunit RNA polymerase II at 4.1-A resolution: implications for the initiation of transcription. Proc Natl Acad Sci USA 100:6969-6973
7. Chen D, Toone WM, Mata J, Lyne R, Burns G, Kivinen K, Brazma A, Jones N, Bähler J (2003) Whole-genome microarrays of fission yeast: characteristics, accuracy, reproducibility, and processing of array data. Mol Biol Cell 14:214-229
8. Choder M (2004) Rpb4 and Rpb7: subunits of RNA polymerase II and beyond. Trends Biochem Sci 29:674-681
9. Dekker N, Speijer D, Grun CH, van den Berg M, de Haan A, Hochstenbach F (2004) Role of the alpha-glucanase Agn1p in fission-yeast cell separation. Mol Biol Cell 15:3903-3914
10. Edwards AM, Kane CM, Young RA, Kornberg RD (1991) Two dissociable subunits of yeast RNA polymerase II stimulate the initiation of transcription at a promoter in vitro. J Biol Chem 266:71-75
11. Grallert A, Grallert B, Zilahi E, Szilagyi Z, Sipiczki M (1999) Eleven novel sep genes of Schizosaccharomyces pombe required for efficient cell separation and sexual differentiation. Yeast 15:669-686
12. Jenkins CC, Mata J, Crane RF, Thomas B, Akoulitchev A, Bähler J, Norbury CJ (2005) Activation of AP-1-dependent transcription by a truncated translation initiation factor. Eukaryot Cell 4:1840-1850
13. Kimura M, Suzuki H, Ishihama A (2002) Formation of a carboxyterminal domain phosphatase (Fcp1)/TFIIF/RNA polymerase II (pol II) complex in Schizosaccharomyces pombe involves direct interaction between Fcp1 and the Rpb4 subunit of pol II. Mol Cell Biol 22:1577-1588
14. Lee KM, Miklos I, Du H, Watt S, Szilagyi Z, Saiz JE, Madabhushi R, Penkett CJ, Sipiczki M, Bähler J, Fisher RP (2005) Impairment of the TFIIH-associated CDK-activating kinase selectively affects cell cycle-regulated gene expression in fission yeast. Mol Biol Cell 16:2734-2745
15. Leupold U (1970) Genetical methods for Schizosaccharomyces pombe. Methods Cell Physiol 4:169-177
16. Li Y, Flanagan PM, Tschochner H, Kornberg RD (1994) RNA polymerase II initiation factor interactions and transcription start site selection. Science 263:805-807
17. Linder K, Gregán J, Montgomery S, Kearsey SE (2002) Essential role of MCM proteins in premeiotic DNA replication. Mol Biol Cell 13:435-444
18. Lindner P (1893) Schizosaccharomyces pombe n. Sp., ein neuer Gährungserreger. Wochenschr Brauerei 10:1298-1300
19. Longtine MS, DeMarini DJ, Valencik ML, Al-Awar OS, Fares H, Virgilio CD, Pringle JR (1996) The septins: roles in cytokinesis and other processes. Curr Opin Cell Biol 8:106-119
20. Lotan R, Bar-On VG, Harel-Sharvit L, Duek L, Melamed D, Choder M (2005) The RNA polymerase II subunit Rpb4p mediates decay of a specific class of mRNAs. Genes Dev 19:3004-3016
21. Lyne R, Burns G, Mata J, Penkett CJ, Rustici G, Chen D, Langford C, Vetrie D, Bähler J (2003) Whole-genome microarrays of fission yeast: characteristics, accuracy, reproducibility, and processing of array data. BMC Genomics 4:27
22. Maillet I, Buhler JM, Sentenac A, Labarre J (1999) Rpb4p is necessary for RNA polymerase II activity at high temperature. J Biol Chem 274:22586-22590
23. Martín-Cuadrado AB, Dueñas E, Sipiczki M, Vázquez de Aldana CR, Del Rey F (2003) The endo-beta-1,3-glucanase eng1p is required for dissolution of the primary septum during cell separation in Schizosaccharomyces pombe. J Cell Sci 116:1689-1698
24. Mata J, Lyne R, Burns G, Bähler J (2002) The transcriptional program of meiosis and sporulation in fission yeast. Nat Genet 32:143-147
25. Mitsuzawa H, Ishihama A (2004) RNA polymerase II transcription apparatus in Schizosaccharomyces pombe. Curr Genet 44:287-294
26. Mitsuzawa H, Kanda E, Ishihama A (2003) Rpb7 subunit of RNA polymerase II interacts with an RNA-binding protein involved in processing of transcripts. Nucl Acids Res 31:4696-4701
27. Mitsuzawa H, Kimura M, Kanda E, Ishihama A (2005) Glyceraldehyde-3- phosphate dehydrogenase and actin associate with RNA polymerase II and interact with its Rpb7 subunit. FEBS Lett 579:48-52
28. Moreno S, Klar A, Nurse P (1991) Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol 194:795-823
29. Orlicky SM, Tran PT, Sayre MH, Edwards AM (2001) Dissociable Rpb4-Rpb7 subassembly of RNA polymerase II binds to single-strand nucleic acid and mediates a post-recruitment step in transcription initiation. J Biol Chem 276:10097-10102
30. Pillai B, Sampath V, Sharma N, Sadhale P (2001) Rpb4, a non-essential subunit of core RNA polymerase II of Saccharomyces cerevisiae is important for activated transcription of a subset of genes. J Biol Chem 276:30641-30647
31. Pillai B, Verma J, Abraham A, Francis P, Kumar Y, Tatu U, Brahmachari SK, Sadhale PP (2003) Whole genome expression profiles of yeast RNA polymerase II core subunit, Rpb4, in stress and nonstress conditions. J Biol Chem 278:3339-3346
32. Rustici G, Mata J, Kivinen K, Lió P, Penkett CJ, Burns G, Hayles J, Brazma A, Nurse P, Bähler J (2004) Periodic gene expression program of the fission yeast cell cycle. Nat Genet 36:809-817
33. Sakurai H, Mitsuzawa H, Kimura M, Ishihama A (1999) The Rpb4 subunit of fission yeast Schizosaccharomyces pombe RNA polymerase II is essential for cell viability and similar in structure to the corresponding subunits of higher eukaryotes. Mol Cell Biol 19:7511-7518
34. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual, 2nd edn. Cold Spring Harbor Laboratory, Cold Spring Harbor
35. Shpakovski GV, Gadal O, Labarre-Mariotte S, Lebedenko EN, Miklos I, Sakurai H, Proshkin SA, Van Mullem V, Ishihama A, Thuriaux P (2000) Functional conservation of RNA polymerase II in fission and budding yeasts. J Mol Biol 295:1119-1127
36. Sipiczki M, Grallert B, Miklos I (1993) Mycelial and syncytial growth in Schizosaccharomyces pombe induced by novel septation mutations. J Cell Sci 104:485-493
37. Spåhr H, Samuelsen CO, Baraznenok V, Ernest I, Huylebroeck D, Remacle JE, Samuelsson T, Kieselbach T, Holmberg S, Gustafsson CM (2001) Analysis of Schizosaccharomyces pombe mediator reveals a set of essential subunits conserved between yeast and metazoan cells. Proc Natl Acad Sci USA 98:11985-11990
38. Spåhr H, Khorosjutina O, Baraznenok V, Linder T, Samuelsen CO, Hermand D, Makela TP, Holmberg S, Gustafsson CM (2003) Mediator influences Schizosaccharomyces pombe RNA polymerase II-dependent transcription in vitro. J Biol Chem 278:51301-51306
39. Sugiura R, Toda T, Shuntoh H, Yanagida M, Kuno T (1998) pmp1+ , a suppressor of calcineurin deficiency, encodes a novel MAP kinase phosphatase in fission yeast. EMBO J 17:140-148
40. Tasto JJ, Morrell JL, Gould KL (2003) An anillin homologue, Mid2p, acts during fission yeast cytokinesis to organize the septin ring and promote cell separation. J Cell Biol 160:1093-1103
41. Toda T, Dhut S, Superti-Furga G, Gotoh Y, Nishida E, Sugiura R, Kuno T (1996) The fission yeast pmk1+ gene encodes a novel mitogen-activated protein kinase homolog which regulates cell integrity and functions coordinately with the protein kinase C pathway. Mol Cell Biol 16:6752-6764
42. Toyama R, Okayama H (1990) Human chorionic gonadotropin alpha and human cytomegalovirus promoters are extremely active in the fission yeast Schizosaccharomyces pombe. FEBS Lett 268:217-221
43. Wang H, Tang X, Liu J, Trautmann S, Balasundaram D, McCollum D, Balasubramanian MK (2002) The multiprotein exocyst complex is essential for cell separation in Schizosaccharomyces pombe. Mol Biol Cell 13:515-529
44. Wong KC, Naqvi1 NI, Iino Y, Yamamoto M, Balasubramanian MK (2000) Fission yeast Rng3p: an UCS-domain protein that mediates myosin II assembly during cytokinesis. J Cell Sci 113:2421-2432
45. Woychik N, Young RA (1989) RNA polymerase II subunit RPB4 is essential for high- and low-temperature yeast cell growth. Mol Cell Biol 9:2854-2859
46. Yoshida T, Toda T, Yanagida M (1994) A calcineurin-like gene ppb1+ in fission yeast: mutant defects in cytokinesis, cell polarity, mating and spindle pole body positioning. J Cell Sci 107:1725-1735