Human RBM28 protein is a specific nucleolar component of the spliceosomal snRNPs

Biological Chemistry

Volumn 387, Issue 10-11, 2006, Pages 1455-1460

  Damianov, Andrey ^a,c   Kann, Michael ^a,d   Lane, William S ^b   Bindereif, Albrecht ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b HARVARD UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

Nucleolus; snRNA; snRNP; Splicing

Indexed keywords

BINDING PROTEIN; RNA BINDING MOTIF PROTEIN 28; SMALL NUCLEAR RNA; UNCLASSIFIED DRUG;

BIOGENESIS; CELL LYSATE; CONFERENCE PAPER; CONTROLLED STUDY; HELA CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DETERMINATION; RNA SPLICING; SPLICEOSOME;

CELL NUCLEOLUS; HELA CELLS; HUMANS; MASS SPECTROMETRY; NUCLEAR PROTEINS; PROTEIN BINDING; RIBONUCLEOPROTEINS, SMALL NUCLEAR; SPLICEOSOMES;

EID: 33750624483     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2006.182     Document Type: Conference Paper

References (32)

1. Achsel, T., Brahms, H., Kastner, B., Bachi, A., Wilm, M., and Lührmann, R. (1999). A doughnut-shaped heteromer of human Sm-like proteins binds to the 3′-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro. EMBO J. 18, 5789-5802.
2. Bell, M., Schreiner, S., Damianov, A., Reddy, R., and Bindereif, A. (2002). p110, a novel human U6 snRNP protein and U4/U6 snRNP recycling factor. EMBO J. 21, 2724-2735.
3. Berges, T., Petfalski, E., Tollervey, D., and Hurt, E.C. (1994). Synthetic lethality with fibrillarin identifies NOP77p, a nucleolar protein required for pre-rRNA processing and modification. EMBO J. 13, 3136-3148.
4. Booth, B.L. Jr. and Pugh, B.F. (1997). Identification and characterization of a nuclease specific for the 3′ end of the U6 small nuclear RNA. J. Biol. Chem. 272, 984-991.
5. Damianov, A., Schreiner, S., and Bindereif, A. (2004). Recycling of the U12-type spliceosome requires p110, a component of the U6atac snRNP. Mol. Cell. Biol. 24, 1700-1708.
6. Darzacq, X., Jady, B.E., Verheggen, C., Kiss, A.M., Bertrand, E., and Kiss, T. (2002). Cajal body-specific small nuclear RNAs: a novel class of 2′-O-methylation and pseudouridylation guide RNAs. EMBO J. 21, 2746-2756.
7. Dignam, J.D., Lebovitz, R.M., and Roeder, R.G. (1983). Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11, 1475-1489.
8. Ganot, P., Jady, B.E., Bortolin, M.L., Darzacq, X., and Kiss, T. (1999). Nucleolar factors direct the 2′-O-ribose methylation and pseudouridylation of U6 spliceosomal RNA. Mol. Cell. Biol. 19, 6906-6917.
9. Gerbi, S.A. and Lange, T.S. (2002). All small nuclear RNAs (snRNAs) of the [U4/U6.U5] Tri-snRNP localize to nucleoli; identification of the nucleolar localization element of U6 snRNA. Mol. Biol. Cell 13, 3123-3137.
10. Gerbi, S.A., Borovjagin, A.V., Odreman, F.E., and Lange, T.S. (2003). U4 snRNA nucleolar localization requires the NHPX/15.5-kDa protein binding site but not Sm protein or U6 snRNA association. J. Cell. Biol. 162, 821-832.
11. Jady, B.E. and Kiss, T. (2001). A small nucleolar guide RNA functions both in 2′-O-ribose methylation and pseudouridylation of the U5 spliceosomal RNA. EMBO J. 20, 541-551.
12. Jady, B.E., Darzacq, X., Tucker, K.E., Matera, A.G., Bertrand, E., and Kiss, T. (2003). Modification of Sm small nuclear RNAs occurs in the nucleoplasmic Cajal body following import from the cytoplasm. EMBO J. 22, 1878-1888.
13. Kiss, T. (2004). Biogenesis of small nuclear RNPs. J. Cell Sci. 117, 5949-5951.
14. Kiss, A.M., Jady, B.E., Darzacq, X., Verheggen, C., Bertrand, E., and Kiss, T. (2002). A Cajal body-specific pseudouridylation guide RNA is composed of two box H/ACA snoRNA-like domains. Nucleic Acids Res. 30, 4643-4649.
15. Lund, E. and Dahlberg, J.E. (1992). Cyclic 2′,3′-phosphates and nontemplated nucleotides at the 3′ end of spliceosomal U6 small nuclear RNAs. Science 255, 327-330.
16. Marchler-Bauer, A. and Bryant, S.H. (2004). CD-Search: protein domain annotations on the fly. Nucleic Acids Res. 32, W327-W331.
17. Mattaj, I.W. (1986). Cap trimethylation of U snRNA is cytoplasmic and dependent on U snRNP protein binding. Cell 46, 905-911.
18. Mougin, A., Gottschalk, A., Fabrizio, P., Lührmann, R., and Branlant, C. (2002). Direct probing of RNA structure and RNA-protein interactions in purified HeLa cells and yeast spliceosomal U4/U6.U5 tri-snRNP particles. J. Mol. Biol. 317, 631-649.
19. Palacios, I., Hetzer, M., Adam, S.A., and Mattaj, I.W. (1997). Nuclear import of U snRNPs requires importin β. EMBO J. 16, 6783-6792.
20. Pannone, B.K., Xue, D., and Wolin, S.L. (1998). A role for the yeast La protein in U6 snRNP assembly: evidence that the La protein is a molecular chaperone for RNA polymerase III transcripts. EMBO J. 17, 7442-7453.
21. Seipelt, R.L., Zheng, B., Asuru, A., and Rymond, B.C. (1999). U1 snRNA is cleaved by RNase III and processed through an Sm site-dependent pathway. Nucleic Acids Res. 27, 587-595.
22. Singh, R. and Reddy, R. (1989). Gamma-monomethyl phosphate: a cap structure in spliceosomal U6 small nuclear RNA. Proc. Natl. Acad. Sci. USA 86, 8280-8283.
23. Sleeman, J.E. and Lamond, A.I. (1999). Newly assembled snRNPs associate with coiled bodies before speckles, suggesting a nuclear snRNP maturation pathway. Curr. Biol. 9, 1065-1074.
24. Sun, C. and Woolford, J.L. Jr. (1994). The yeast NOP4 gene product is an essential nucleolar protein required for pre-rRNA processing and accumulation of 60S ribosomal subunits. EMBO J. 13, 3127-3135.
25. Sun, C. and Woolford, J.L. Jr. (1997). The yeast nucleolar protein Nop4p contains four RNA recognition motifs necessary for ribosome biogenesis. J. Biol. Chem. 272, 25345-25352.
26. Terns, M.P., Lund, E., and Dahlberg, J.E. (1992). 3′-End-dependent formation of U6 small nuclear ribonucleoprotein particles in Xenopus laevis oocyte nuclei. Mol. Cell. Biol. 12, 3032-3040.
27. Trippe, R., Sandrock, B., and Benecke, B.J. (1998). A highly specific terminal uridylyl transferase modifies the 3′-end of U6 small nuclear RNA. Nucleic Acids Res. 26, 3119-3126.
28. Trippe, R., Guschina, E., Hossbach, M., Urlaub, H., Lührmann, R., and Benecke, B.H. (2006). Identification, cloning, and functional analysis of the human U6 snRNA-specific terminal uridylyl transferase. RNA 12, 1494-1504.
29. Tycowski, K.T., You, Z.H., Graham, P.J., and Steitz, J.A. (1998). Modification of U6 spliceosomal RNA is guided by other small RNAs. Mol. Cell 2, 629-638.
30. Will, C.L. and Lührmann, R. 2001. Spliceosomal UsnRNP biogenesis, structure and function. Curr. Opin. Cell Biol. 13, 290-301.
31. Wolff, T. and Bindereif, A. (1992). Reconstituted mammalian U4/U6 snRNP complements splicing: a mutational analysis. EMBO J. 11, 345-359.
32. Yong, J., Wan, L., and Dreyfuss, G. (2004). Why do cells need an assembly machine for RNA-protein complexes? Trends Cell Biol. 14, 226-232.