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Volumn 47, Issue 50, 2006, Pages 8969-8972

From aldehydes to nitriles, a general and high yielding transformation using HOF·CH3CN complex

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE; CYANIC ACID DERIVATIVE; HYDRAZONE DERIVATIVE; NITRILE;

EID: 33750618820     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2006.10.014     Document Type: Article
Times cited : (28)

References (36)
  • 9
    • 33750621976 scopus 로고    scopus 로고
    • note
    • 4. Evaporation of the solvent gave the target N,N-dimethylhydrazone derivative, which in certain cases was purified by flash column chromatography (petroleum ether/ethyl acetate as eluent). The yields of N,N-dimethylhydrazones varied between 90% and 95%.
  • 12
    • 33750626978 scopus 로고    scopus 로고
    • note
    • 2O in a regular glass reactor. The development of the oxidizing power was monitored by reacting aliquots with an acidic aqueous solution of KI. The liberated iodine was then titrated with thiosulfate. The typical concentrations of the oxidizing reagent were around 0.4-0.6 mol/L.
  • 26
    • 33750614284 scopus 로고    scopus 로고
    • note
    • 13C NMR (CN): 115-125 ppm.
  • 36
    • 33750625375 scopus 로고    scopus 로고
    • note
    • 2, to chlorine reveals that it is more complicated to work with the latter since it tends to corrode the cylinders' heads. Working with bromine is associated with many accidents and fatalities. Experimenting with the widely used HCN, HF, perchlorates and alike is surely more dangerous. Diluted fluorine can be passed through copper, monel, stainless steel, or Teflon tubes without much trouble.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.