Apolipoprotein E deficiency increased microglial activation/CCR3 expression and hippocampal damage in kainic acid exposed mice

Experimental Neurology

Volumn 202, Issue 2, 2006, Pages 373-380

  Duan, Rui Sheng ^a   Chen, Zhiguo ^a   Dou, Ying Chun ^a   Concha Quezada, Hernan ^b   Nennesmo, Inger ^a   Adem, Abdu ^c   Winblad, Bengt ^a   Zhu, Jie ^a,d  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^d JILIN UNIVERSITY   (China)

Author keywords

apoE; CCR3; Kainic acid; Microglia; Neurodegeneration

Indexed keywords

APOLIPOPROTEIN E; CHEMOKINE RECEPTOR CCR3; KAINIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DAMAGE; BRAIN REGION; CONTROLLED STUDY; HIPPOCAMPUS; HISTOPATHOLOGY; HYPERLIPOPROTEINEMIA TYPE 3; KNOCKOUT MOUSE; LOCOMOTION; MALE; MICROGLIA; MORTALITY; MOUSE; NERVE CELL LESION; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REARING; SCORING SYSTEM; SEIZURE; WILD TYPE;

ANALYSIS OF VARIANCE; ANIMALS; ANTIGENS, CD11B; ANTIGENS, CD86; APOLIPOPROTEINS E; BEHAVIOR, ANIMAL; ENZYME ACTIVATION; EXCITATORY AMINO ACID AGONISTS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HIPPOCAMPUS; HISTOCOMPATIBILITY ANTIGENS CLASS II; IMMUNOHISTOCHEMISTRY; KAINIC ACID; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; MOTOR ACTIVITY; NEUROLOGIC EXAMINATION; RECEPTORS, CHEMOKINE;

EID: 33750609665     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2006.06.013     Document Type: Article

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