Creatine synthesis: An undergraduate organic chemistry laboratory experiment

Journal of Chemical Education

Volumn 83, Issue 11, 2006, Pages 1654-1657

  Smith, Andri L ^a   Tan, Paula ^a,b  

^a QUINNIPIAC UNIVERSITY   (United States)

^b Acadia Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIUM COMPOUNDS; BIOCHEMISTRY; CURRICULA; SODIUM CHLORIDE; SYNTHESIS (CHEMICAL);

AMMONIUM HYDROXIDE; CREATINE; CYANAMIDE; N-METHYLGLYCINE; SARCOSINE;

NITROGEN COMPOUNDS;

EID: 33750538260     PISSN: 00219584     EISSN: None     Source Type: Journal    
DOI: 10.1021/ed083p1654     Document Type: Article

References (27)

1. Giffin, G. A.; Boone, S. R.; Cole, R. S.; McKay, S. E.; Kopitzke, R. J. Chem. Educ. 2002, 79, 813-817.
2. Clark, J. F. J. Athletic Training 1997, 32, 45-51.
3. Chiang, R. Athletic Supplements: Creatine. Ergogenic Aids. http://www.geocities.com/HotSprings/Spa/9971/creatine.html (accessed Jul 2006).
4. Balsom, P. D.; Soderlund, K.; Ekblom, B. Sports Med. 1994, 18, 268-280.
5. Wyss, M.; Kaddurah-Daouk, R. Physiol. Rev. 2000, 80, 1107-1213.
6. Guyton, A. C.; Hall, J. E. Textbook of Medical Physiology, 10th ed.; W. B. Saunders Co.: Philadelphia, 2000.
7. Sipila, I.; Simell, O.; Vannas, A. N. Engl. J. Med 1981, 304, 867-870.
8. Vannas-Sulonen, K.; Sipila, I.; Vannas, A.; Simell, O.; Rapola, J. Ophthalmology 1985, 92, 1719-1727.
9. Gyrate Atrophy of the Choroid and Retina. National Center for Biotechnology Information. http://www.ncbi.nlm.nih.gov/books/ bv.fcgi?call=bv.View..ShowSection&rid=gnd.section.128 (accessed Jul 2006).
10. Rubin, M. Neurol. Alert 2000, 18, 87.
11. Sullivan, P. G.; Geiger, J. D.; Mattson, M. P.; Scheff, S. W. Ann. Neurol. 2000, 48, 723-729.
12. Zhang, W.; Narayanan, M.; Friedlander, R. M. Ann. Neurol. 2003, 53, 267-270.
13. Groeneveld, G. J.; Veldink, J. H.; van der Tweel, I.; Kalmijn, S.; Beijer, C.; de Visser, M.; Wokke, J. H. J.; Franssen, H.; van den Berg, L. H. Ann. Neurol. 2003, 53, 437-445.
14. Williams, M. H.; Kreider, R. B.; Branch, J. D. Creatine: The Power Supplement; Human Kinetics: Champaign, IL, 1999.
15. Creatine Report. Vitality Research Institute Metabolite Report. http://www.primev.com/Creatine.htm (accessed Jul 2006).
16. Juhn, M. S. The Physician and Sportsmedicine 1999, 27, 47-52.
17. Meiggs, R. Committee Continues To Monitor Creatine Use in Sports. The NCAA News. http://www.ncaa.org/wps/portal/newsdetail?WCM_GLOBAL_CONTEXT= /wps/wcm/connect/NCAA/NCAA+News/NCAA+News+Online/Association-wide/ Committee+continues+to+monitor+creatine+use+in+sports+-+4-12- 04&TITLE=Committee+continues+to+monitor+creatine+use+in+sports+-+4- 12-04 (accessed Aug 2006).
18. NCAA Banned-Drug Classes 2006-2007. National Collegiate Athletic Association. http://www1.ncaa.org/membership/ed_outreach/health-safety/ drug_testing/banned_drug_classes.pdf (accessed Aug 2006).
19. T0he 2006 Prohibited List, International Standard. The World Anti-Doping Code. World Anti-Doping Agency. http://www.wada-ama.org/rtecontent/ document/2006_LIST.pdf (accessed Aug 2006).
20. St. Philip, E. "Legal Steroid" Enhances Performance. Discovery Channel Canada. http://www.exn.ca/templates/printstory.asp? PageName=Discovery&story_id=1996112102 (accessed Jul 2006).
21. McGuine, T.A.; Sullivan, J. C.; Bernhardt, D. A. Wisc. Med. J. 2002, 101, 25-30. http://www.wisconsinmedicalsociety.org/uploads/wmj/ 101-2-McGuine.pdf (accessed Aug 2006).
22. LaBotz, M.; Smith, B. W. Clin. J. Sport Med. 1999, 9, 167-169.
23. Olson, E. Creatine Use Common for CWS Teams. The Omaha World Herald, May 29, 1998, Sports, p 39.
24. Greenaway, W.; Whatley, F. R. J. Labelled Compounds and Radiopharmaceuticals 1978, 14, 611-615.
25. Williamson, K. L. Macroscale and Microscale Organic Experiments, 4th ed.; Houghton Mifflin Company: Boston, 2003.
26. Cho, Y.-B.; Stedman, R. J.; Paik, W. K. J. Korean Chem. Soc. 1985, 29, 419-425.
27. The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals, 11th ed.; Budavari, S., Eds.; Merck & Co. Inc.: Rahway, NJ, 1989.