Synthesis of amino acid derived seven-membered lactams by RCM and their evaluation against HIV protease

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 24, 2006, Pages 8323-8331

  Zaman, Shazia ^a   Campaner, Pietro ^b   Abell, Andrew D ^a  

^a UNIVERSITY OF CANTERBURY   (New Zealand)

^b UNIVERSITY OF TRIESTE   (Italy)

Author keywords

Diol; HIV protease; Lactams; Ring closing metathesis

Indexed keywords

ALKADIENE; ALKENE; AMINO ACID DERIVATIVE; EPOXIDE; LACTAM DERIVATIVE; PROTEINASE; PROTEINASE INHIBITOR; TERT BUTYL (1 BENZYL 5,6 DIHYDROXY 2 OXOAZEPAN 3 YL)CARBAMATE; TERT BUTYL (1 BENZYL 5,6 DIHYDROXY 4 PHENYL 2 OXOAZEPAN 3 YL)CARBAMATE; TERT BUTYL (1 BENZYL 5,6 DIHYDROXY 7 BENZYL 2 OXOAZEPAN 3 YL)CARBAMATE; TERT BUTYL (2,3 DIBENZYL 4 OXO 8 OXA 3 AZABICYCLO[5.1.0]OCT 5 YL)CARBAMATE; TERT BUTYL (3 BENZYL 4 OXO 8 OXA 3 AZABICYCLO[5.1.0]OCT 5 YL)CARBAMATE; TERT BUTYL (3 BENZYL 6 PHENYL 4 OXO 8 OXA 3 AZABICYCLO[5.1.0]OCT 5 YL)CARBAMATE; UNCLASSIFIED DRUG;

ARTICLE; DIHYDROXYLATION; DRUG SYNTHESIS; EPOXIDATION; HYDROXYLATION; RING CLOSING METATHESIS;

HIV PROTEASE; HIV PROTEASE INHIBITORS; HIV-1; HUMANS; LACTAMS;

EID: 33750525784     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.09.009     Document Type: Article

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