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Volumn 62, Issue 4, 2006, Pages 958-969

Molecular basis for control of conjugation by bacterial pheromone and inhibitor peptides

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BETA GALACTOSIDASE; LIGAND; PEPTIDE DERIVATIVE; PHEROMONE; PROTEIN INHIBITOR; PROTEIN PRGX; TETRAMER; UNCLASSIFIED DRUG;

EID: 33750493628     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2006.05434.x     Document Type: Article
Times cited : (70)

References (31)
  • 1
    • 0035109125 scopus 로고    scopus 로고
    • Dominant-negative mutants of prgX: Evidence for a role for PrgX dimerization in negative regulation of pheromone-inducible conjugation
    • Bae, T., and Dunny, G.M. (2001) Dominant-negative mutants of prgX: evidence for a role for PrgX dimerization in negative regulation of pheromone-inducible conjugation. Mol Microbiol 39: 1307-1320.
    • (2001) Mol Microbiol , vol.39 , pp. 1307-1320
    • Bae, T.1    Dunny, G.M.2
  • 2
    • 0034615783 scopus 로고    scopus 로고
    • Analysis of expression of prgX, a key negative regulator of the transfer of the Enterococcus faecalis pheromone-inducible plasmid pCF10
    • Bae, T., Clerc-Bardin, S., and Dunny, G.M. (2000) Analysis of expression of prgX, a key negative regulator of the transfer of the Enterococcus faecalis pheromone-inducible plasmid pCF10. J Mol Biol 297: 861-875.
    • (2000) J Mol Biol , vol.297 , pp. 861-875
    • Bae, T.1    Clerc-Bardin, S.2    Dunny, G.M.3
  • 3
    • 0036308374 scopus 로고    scopus 로고
    • Two targets in pCF10 DNA for PrgX binding: Their role in production of Qa and prgX mRNA and in regulation of pheromone-inducible conjugation
    • Bae, T., Kozlowicz, B., and Dunny, G.M. (2002) Two targets in pCF10 DNA for PrgX binding: their role in production of Qa and prgX mRNA and in regulation of pheromone-inducible conjugation. J Mol Biol 315: 995-1007.
    • (2002) J Mol Biol , vol.315 , pp. 995-1007
    • Bae, T.1    Kozlowicz, B.2    Dunny, G.M.3
  • 4
    • 0346334401 scopus 로고    scopus 로고
    • Characterization of cis-acting prgQ mutants: Evidence for two distinct repression mechanisms by Qa RNA and PrgX protein in pheromone-inducible enterococcal plasmid pCF10
    • Bae, T., Kozlowicz, B.K., and Dunny, G.M. (2004) Characterization of cis-acting prgQ mutants: evidence for two distinct repression mechanisms by Qa RNA and PrgX protein in pheromone-inducible enterococcal plasmid pCF10. Mol Microbiol 51: 271-281.
    • (2004) Mol Microbiol , vol.51 , pp. 271-281
    • Bae, T.1    Kozlowicz, B.K.2    Dunny, G.M.3
  • 5
  • 6
    • 4544272190 scopus 로고    scopus 로고
    • Enterococcal peptide sex pheromones: Synthesis and control of biological activity
    • Chandler, J.R., and Dunny, G.M. (2004) Enterococcal peptide sex pheromones: synthesis and control of biological activity. Peptides 25: 1377-1388.
    • (2004) Peptides , vol.25 , pp. 1377-1388
    • Chandler, J.R.1    Dunny, G.M.2
  • 7
    • 21844463033 scopus 로고    scopus 로고
    • Specific control of endogenous cCF10 pheromone by a conserved domain of the pCF10-encoded regulatory protein PrgY in Enterococcus faecalis
    • Chandler, J.R., Flynn, A.R., Bryan, E.M., and Dunny, G.M. (2005a) Specific control of endogenous cCF10 pheromone by a conserved domain of the pCF10-encoded regulatory protein PrgY in Enterococcus faecalis. J Bacteriol 187: 4830-4843.
    • (2005) J Bacteriol , vol.187 , pp. 4830-4843
    • Chandler, J.R.1    Flynn, A.R.2    Bryan, E.M.3    Dunny, G.M.4
  • 8
    • 27344455172 scopus 로고    scopus 로고
    • A paracrine peptide sex pheromone also acts as an autocrine signal to induce plasmid transfer and virulence factor expression in vivo
    • Chandler, J.R., Hirt, H., and Dunny, G.M. (2005b) A paracrine peptide sex pheromone also acts as an autocrine signal to induce plasmid transfer and virulence factor expression in vivo. Proc Natl Acad Sci USA 102: 15617-15622.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15617-15622
    • Chandler, J.R.1    Hirt, H.2    Dunny, G.M.3
  • 9
    • 0028962141 scopus 로고
    • Transcriptional analysis of a region of the Enterococcus faecalis plasmid pCF10 involved in positive regulation of conjugative transfer functions
    • Chung, J.W., and Dunny, G.M. (1995) Transcriptional analysis of a region of the Enterococcus faecalis plasmid pCF10 involved in positive regulation of conjugative transfer functions. J Bacteriol 177: 2118-2124.
    • (1995) J Bacteriol , vol.177 , pp. 2118-2124
    • Chung, J.W.1    Dunny, G.M.2
  • 10
    • 0030792814 scopus 로고    scopus 로고
    • Cell-cell communication in gram-positive bacteria
    • Dunny, G.M., and Leonard, B.A. (1997) Cell-cell communication in gram-positive bacteria. Annu Rev Microbiol 51: 527-564.
    • (1997) Annu Rev Microbiol , vol.51 , pp. 527-564
    • Dunny, G.M.1    Leonard, B.A.2
  • 11
    • 0342867597 scopus 로고
    • Induced cell aggregation and mating in Streptococcus faecalis: Evidence for a bacterial sex pheromone
    • Dunny, G.M., Brown, B.L., and Clewell, D.B. (1978) Induced cell aggregation and mating in Streptococcus faecalis: evidence for a bacterial sex pheromone. Proc Natl Acad Sci USA 75: 3479-3483.
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 3479-3483
    • Dunny, G.M.1    Brown, B.L.2    Clewell, D.B.3
  • 12
    • 0022381366 scopus 로고
    • Induction of surface exclusion (entry exclusion) by Streptococcus faecalis sex pheromones: Use of monoclonal antibodies to identify an inducible surface antigen involved in the exclusion process
    • Dunny, G.M., Zimmerman, D.L., and Tortorello, M.L. (1985) Induction of surface exclusion (entry exclusion) by Streptococcus faecalis sex pheromones: use of monoclonal antibodies to identify an inducible surface antigen involved in the exclusion process. Proc Natl Acad Sci USA 82: 8582-8586.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 8582-8586
    • Dunny, G.M.1    Zimmerman, D.L.2    Tortorello, M.L.3
  • 13
    • 0034830922 scopus 로고    scopus 로고
    • Peptide pheromone-induced transfer of plasmid pCF10 in Enterococcus faecalis: Probing the genetic and molecular basis for specificity of the pheromone response
    • Dunny, G.M., Antiporta, M.H., and Hirt, H. (2001) Peptide pheromone-induced transfer of plasmid pCF10 in Enterococcus faecalis: probing the genetic and molecular basis for specificity of the pheromone response. Peptides 22: 1529-1539.
    • (2001) Peptides , vol.22 , pp. 1529-1539
    • Dunny, G.M.1    Antiporta, M.H.2    Hirt, H.3
  • 14
    • 0032568644 scopus 로고    scopus 로고
    • Regulation of the pAD1 sex pheromone response of Enterococcus faecalis by direct interaction between the cAD1 peptide mating signal and the negatively regulating, DNA-binding TraA protein
    • Fujimoto, S., and Clewell, D.B. (1998) Regulation of the pAD1 sex pheromone response of Enterococcus faecalis by direct interaction between the cAD1 peptide mating signal and the negatively regulating, DNA-binding TraA protein. Proc Natl Acad Sci USA 95: 6430-6435.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6430-6435
    • Fujimoto, S.1    Clewell, D.B.2
  • 15
    • 54249116230 scopus 로고
    • Genetic regulatory mechanisms in the synthesis of proteins
    • Jacob, F., and Monod, J. (1961) Genetic regulatory mechanisms in the synthesis of proteins. J Mol Biol 3: 318-356.
    • (1961) J Mol Biol , vol.3 , pp. 318-356
    • Jacob, F.1    Monod, J.2
  • 16
    • 0000356656 scopus 로고
    • A graphics model building and refinement system for macromolecules
    • Jones, T.A. (1978) A graphics model building and refinement system for macromolecules. J Appl Cryst 11: 268-272.
    • (1978) J Appl Cryst , vol.11 , pp. 268-272
    • Jones, T.A.1
  • 17
    • 0033081529 scopus 로고    scopus 로고
    • Rapid automated molecular replacement by evolutionary search
    • Kissinger, C.R., Gehlhaar, D.K., and Fogel, D.B. (1999) Rapid automated molecular replacement by evolutionary search. Acta Crystallogr D55: 484-491.
    • (1999) Acta Crystallogr , vol.D55 , pp. 484-491
    • Kissinger, C.R.1    Gehlhaar, D.K.2    Fogel, D.B.3
  • 18
    • 6344275442 scopus 로고    scopus 로고
    • Enterococcus faecalis pheromone-responsive protein PrgX: Genetic separation of positive autoregulatory functions from those involved in negative regulation of conjugative plasmid transfer
    • Kozlowicz, B.K., Bae, T., and Dunny, G.M. (2004) Enterococcus faecalis pheromone-responsive protein PrgX: genetic separation of positive autoregulatory functions from those involved in negative regulation of conjugative plasmid transfer. Mol Microbiol 54: 520-532.
    • (2004) Mol Microbiol , vol.54 , pp. 520-532
    • Kozlowicz, B.K.1    Bae, T.2    Dunny, G.M.3
  • 19
    • 0034830834 scopus 로고    scopus 로고
    • The intracellular function of extracellular signaling peptides
    • Lazazzera, B.A. (2001) The intracellular function of extracellular signaling peptides. Peptides 22: 1519-1527.
    • (2001) Peptides , vol.22 , pp. 1519-1527
    • Lazazzera, B.A.1
  • 20
    • 0030044159 scopus 로고    scopus 로고
    • Enterococcus faecalis pheromone binding protein, PrgZ, recruits a chromosomal oligopeptide permease system to import sex pheromone cCF10 for induction of conjugation
    • Leonard, B.A., Podbielski, A., Hedberg, P.J., and Dunny, G.M. (1996) Enterococcus faecalis pheromone binding protein, PrgZ, recruits a chromosomal oligopeptide permease system to import sex pheromone cCF10 for induction of conjugation. Proc Natl Acad Sci USA 93: 260-264.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 260-264
    • Leonard, B.A.1    Podbielski, A.2    Hedberg, P.J.3    Dunny, G.M.4
  • 21
    • 4544305681 scopus 로고    scopus 로고
    • Peptide signaling in Staphylococcus aureus and other Gram-positive bacteria
    • Lyon, G.J., and Novick, R.P. (2004) Peptide signaling in Staphylococcus aureus and other Gram-positive bacteria. Peptides 9: 1389-1403.
    • (2004) Peptides , vol.9 , pp. 1389-1403
    • Lyon, G.J.1    Novick, R.P.2
  • 22
    • 0003785155 scopus 로고
    • Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
    • Miller, J.H. (1972) Experiments in Molecular Genetics. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, pp. 352-355.
    • (1972) Experiments in Molecular Genetics , pp. 352-355
    • Miller, J.H.1
  • 23
    • 0023718535 scopus 로고
    • Structure of cCF10, a peptide sex pheromone which induces conjugative transfer of the Streptococcus faecalis tetracycline resistance plasmid, pCF10
    • Mori, M., Sakagami, Y., Ishii, Y., Isogai, A., Kitada, C., Fujino, M., et al. (1988) Structure of cCF10, a peptide sex pheromone which induces conjugative transfer of the Streptococcus faecalis tetracycline resistance plasmid, pCF10. J Biol Chem 263: 14574-14578.
    • (1988) J Biol Chem , vol.263 , pp. 14574-14578
    • Mori, M.1    Sakagami, Y.2    Ishii, Y.3    Isogai, A.4    Kitada, C.5    Fujino, M.6
  • 24
    • 0028034250 scopus 로고
    • The prgQ gene of the Enterococcus faecalis tetracycline resistance plasmid pCF10 encodes a peptide inhibitor, iCF10
    • Nakayama, J., Ruhfel, R.E., Dunny, G.M., Isogai, A., and Suzuki, A. (1994) The prgQ gene of the Enterococcus faecalis tetracycline resistance plasmid pCF10 encodes a peptide inhibitor, iCF10. J Bacteriol 176: 7405-7408.
    • (1994) J Bacteriol , vol.176 , pp. 7405-7408
    • Nakayama, J.1    Ruhfel, R.E.2    Dunny, G.M.3    Isogai, A.4    Suzuki, A.5
  • 25
    • 0031888024 scopus 로고    scopus 로고
    • Molecular mechanism of peptide-specific pheromone signaling in Enterococcus faecalis: Functions of pheromone receptor TraA and pheromone-binding protein TraC encoded by plasmid pPD1
    • Nakayama, J., Takanami, Y., Horii, T., Sakuda, S., and Suzuki, A. (1998) Molecular mechanism of peptide-specific pheromone signaling in Enterococcus faecalis: functions of pheromone receptor TraA and pheromone-binding protein TraC encoded by plasmid pPD1. J Bacteriol 180: 449-456.
    • (1998) J Bacteriol , vol.180 , pp. 449-456
    • Nakayama, J.1    Takanami, Y.2    Horii, T.3    Sakuda, S.4    Suzuki, A.5
  • 26
    • 0034946367 scopus 로고    scopus 로고
    • Gelatinase biosynthesis-activating pheromone: A peptide lactone that mediates a quorum sensing in Enterococcus faecalis
    • Nakayama, J., Cao, Y., Horii, T., Sakuda, S., Akkermans, A.D., de Vos, W.M., and Nagasawa, H. (2001) Gelatinase biosynthesis-activating pheromone: a peptide lactone that mediates a quorum sensing in Enterococcus faecalis. Mol Microbiol 41: 145-154.
    • (2001) Mol Microbiol , vol.41 , pp. 145-154
    • Nakayama, J.1    Cao, Y.2    Horii, T.3    Sakuda, S.4    Akkermans, A.D.5    De Vos, W.M.6    Nagasawa, H.7
  • 27
    • 0031059866 scopus 로고    scopus 로고
    • Processing of X-ray diffraction data collected in oscillation mode
    • Otwinowski, O., and Minor, W. (1997) Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol 276: 307-326.
    • (1997) Methods Enzymol , vol.276 , pp. 307-326
    • Otwinowski, O.1    Minor, W.2
  • 28
    • 0033213239 scopus 로고    scopus 로고
    • The finer things in X-ray diffraction data collection
    • Pflugrath, J.W. (1999) The finer things in X-ray diffraction data collection. Acta Crystallogr D55: 1718-1725.
    • (1999) Acta Crystallogr , vol.D55 , pp. 1718-1725
    • Pflugrath, J.W.1
  • 29
    • 0027258080 scopus 로고
    • Cloning and characterization of a region of the Enterococcus faecalis conjugative plasmid, pCF10, encoding a sex pheromone-binding function
    • Ruhfel, R.E., Manias, D.A., and Dunny, G.M. (1993) Cloning and characterization of a region of the Enterococcus faecalis conjugative plasmid, pCF10, encoding a sex pheromone-binding function. J Bacteriol 175: 5253-5259.
    • (1993) J Bacteriol , vol.175 , pp. 5253-5259
    • Ruhfel, R.E.1    Manias, D.A.2    Dunny, G.M.3
  • 30
    • 29444442479 scopus 로고    scopus 로고
    • Structure of peptide sex pheromone receptor PrgX and PrgX/pheromone complexes and regulation of conjugation in Enterococcus faecalis
    • Shi, K., Brown, C.K., Gu, Z., Kozlowicz, B.K., Dunny, G.M., Ohlendorf, D.H., and Earhart, C.A. (2005) Structure of peptide sex pheromone receptor PrgX and PrgX/pheromone complexes and regulation of conjugation in Enterococcus faecalis. Proc Natl Acad Sci USA 102: 18596-18601.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 18596-18601
    • Shi, K.1    Brown, C.K.2    Gu, Z.3    Kozlowicz, B.K.4    Dunny, G.M.5    Ohlendorf, D.H.6    Earhart, C.A.7
  • 31
    • 0025271595 scopus 로고
    • Regulation of the pAD1 sex pheromone response in Enterococcus faecalis: Effects of host strain and traA, traB, and C region mutants on expression of an e region pheromone-inducible lacZ fusion
    • Weaver, K.E., and Clewell, D.B. (1990) Regulation of the pAD1 sex pheromone response in Enterococcus faecalis: effects of host strain and traA, traB, and C region mutants on expression of an E region pheromone-inducible lacZ fusion. J Bacteriol 172: 2633-2641.
    • (1990) J Bacteriol , vol.172 , pp. 2633-2641
    • Weaver, K.E.1    Clewell, D.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.