An Irish case of pulmonary emboli secondary to clozapine therapy

Irish Journal of Psychological Medicine

Volumn 23, Issue 1, 2006, Pages 36-37

  O'Luanaigh, Conor ^a   Scully, Paul ^b  

^a ST PATRICK S HOSPITAL   (Ireland)

^b ST JAMES S HOSPITAL   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; CHLORPROMAZINE; CLOZAPINE; FLUPENTIXOL; FLUPHENAZINE; HEPARIN; RISPERIDONE; SULPIRIDE; THIORIDAZINE; WARFARIN;

ADULT; ANAMNESIS; ANGIOGRAPHY; ARTICLE; BLOOD EXAMINATION; BLURRED VISION; CARDIOVASCULAR RISK; CASE REPORT; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; DIZZINESS; ELECTROCARDIOGRAM; HOSPITAL READMISSION; HUMAN; HYPERSALIVATION; INTERNATIONAL NORMALIZED RATIO; IRELAND; LUNG EMBOLISM; MALE; PARANOID SCHIZOPHRENIA; PHYSICAL EXAMINATION; PSYCHIATRIC DEPARTMENT; SEPSIS; TREATMENT FAILURE;

EID: 33750479388     PISSN: 07909667     EISSN: 07909667     Source Type: Journal    
DOI: 10.1017/S0790966700009472     Document Type: Article

References (12)

1. Kane J, Honifeld G, Singer J et al. Clozapine for the treatment resistant schizophrenic. Archives of General Psychiatry 1988; 45: 789-796
2. Ungvari G. Neuroleptic related sudden death (proven or a mere hypothesis?). Pharmacopsychiatry 1980; 13: 29-33
3. Hafner H, Brehm I. Thromboembolic complications in neuroleptic treatment. Compr Psychiatry 1965; 6: 25-34
4. Thomassen R, Vandenbroucke JP, Rosendaal FR. Antipsychotic medication and venous thrombosis. Br J Psychiatry 2001; 179: 63-66
5. Lacika S, Cooper JP. Pulmonary embolus possibly associated with clozapine treatment. Can J Psychiatry 1999; 44: 396-397
6. Hagg S, Spigset O, Soderstrom TG. Association of venous thromboembolism and clozapine. Lancet 2000; 335: 1155-1156.
7. Walker AM, Lanza LL, Arellano F, Rothman KJ. Mortality in current and former users of clozapine. Epidemiology 1997; 8: 671-677
8. Davis S, Kern HB, Asokan R. Antiphospholipid antibodies associated with clozapine treatment. Am J Hematology 1994; 46: 166-167
9. Canoso RT, de Oliveira RM. Chlorpromazine-induced anticardiolipin antibodies and lupus anticoagulant: absence of thrombosis. Am J Hematology 1988; 27: 272-275
10. Boullin DJ, Woods HF, Grimes RPJ, Grahame-Smith DG, Wiles D et al. Increased platelet aggregation responses to 5-hydroxytryptamine in patients taking chlorpromazine. Br J Clin Pharmacology 1975; 2: 29-35
11. Orr MW, Boullin DJ. The relationship between changes in 5-HT induced platelet aggregation and clinical state in patients treated with fluphenazine. Br J Clin Pharmacology 1976; 3: 925-928
12. Love RC. Novel versus conventional antipsychotic drugs. Pharmacotherapy 1996; 16: 6S-10S