c-Abl phosphorylates Hdm2 at tyrosine 276 in response to DNA damage and regulates interaction with ARF

Oncogene

Volumn 25, Issue 50, 2006, Pages 6666-6671

  Dias, S S ^a   Milne, D M ^a   Meek, D W ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

ARF; c Abl; DNA damage; Hdm2; p53; Phosphorylation

Indexed keywords

ABELSON KINASE; ARF PROTEIN; PROTEIN HDM2; PROTEIN MDM2; PROTEIN TYROSINE 276; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DNA DAMAGE; ENZYME PHOSPHORYLATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INTERACTION; PROTEIN METABOLISM; PROTEIN TARGETING; WESTERN BLOTTING;

ANIMALS; CELL CYCLE PROTEINS; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA DAMAGE; DNA-BINDING PROTEINS; HUMANS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-ABL; PROTO-ONCOGENE PROTEINS C-MDM2; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

ATAXIA TELANGIECTASIA;

EID: 33750478380     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1209671     Document Type: Article

References (16)

1. Appella E, Anderson CW. (2001). Eur J Biochem 268: 2764-2772.
2. Barila D, Mangano R, Gonfloni S, Kretzschmar J, Moro M, Bohmann D et al. (2000). EMBO J 19: 273-281.
3. Blattner C, Hay TJ, Meek DW, Lane DP. (2002). Mol Cell Biol 22: 6170-6182.
4. Bothner B, Lewis WS, DiGiammarino EL, Weber JD, Bothner SJ, Kriwacki RW. (2001). J Mol Biol 314: 263-277.
5. Goldberg Z, Sionov RV, Berger M, Zwang Y, Perets R, Van Etten RA et al. (2002). EMBO J 21: 3715-3727.
6. Harris SL, Levine AJ. (2005). Oncogene 24: 2899-2908.
7. Kurki S, Peltonen K, Kiviharju T, Latonen L, Ojala P, Meek D et al. (2004). Cancer Cell 5: 465-475.
8. Lu X. (2005). Curr Opin Genet Dev 15: 27-33.
9. Maya R, Balass M, Kim ST, Shkedy D, Leal JF, Shifman O et al. (2001). Genes Dev 15: 1067-1077.
10. Meek DW, Knippschild U. (2003). Mol Cancer Res 1: 1017-1026.
11. Michael D, Oren M. (2003). Semin Cancer Biol 13: 49-58.
12. Saito S, Yamaguchi H, Higashimoto Y, Chao C, Xu Y, Fornace Jr AJ et al. (2003). J Biol Chem 278: 37536-37544.
13. Shaul Y, Ben-Yehoyada M. (2005). Cell Res 15: 33-35.
14. Sionov RV, Coen S, Goldberg Z, Berger M, Bercovich B, Ben-Neriah Y et al. (2001). Mol Cell Biol 21: 5869-5878.
15. Sionov RV, Moallem E, Berger M, Kazaz A, Gerlitz O, Ben-Neriah Y et al. (1999). J Biol Chem 274: 8371-8374.
16. Wu JJ, Afar DE, Phan H, Witte ON, Lam KS. (2002). Comb Chem High Throughput Screen 5: 83-91.