The PKA-CREB system encoded by the honeybee genome

Insect Molecular Biology

Volumn 15, Issue 5, 2006, Pages 551-561

  Eisenhardt, D ^a   Kuhn C ^b   Leboulle, G ^b  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b NONE

Author keywords

bZIP; CREB; Destabilizing elements; Honeybee genome; PKA; Splicing; uORF

Indexed keywords

BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN;

ANIMAL; ARTICLE; BEE; DROSOPHILA; ENZYME ACTIVE SITE; GENE; GENE STRUCTURE; GENETICS; HUMAN; REGULATORY SEQUENCE; SEQUENCE HOMOLOGY;

ANIMALS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; BEES; CATALYTIC DOMAIN; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DROSOPHILA; GENE COMPONENTS; GENES, INSECT; HUMANS; REGULATORY ELEMENTS, TRANSCRIPTIONAL; SEQUENCE HOMOLOGY, AMINO ACID;

APIS MELLIFERA;

EID: 33750458700     PISSN: 09621075     EISSN: 13652583     Source Type: Journal    
DOI: 10.1111/j.1365-2583.2006.00668.x     Document Type: Article

References (49)

1. Abel, T., Bjatt, R. and Maniatis, T. (1992) A Drosophila CREB/ATF transcriptional activator binds to both fat body- and liver-specific regulatory elements. Genes Dev 6: 466-480.
2. Akker, S.A., Smith, P.J. and Chew, S.L. (2001) Nuclear post-transcriptional control of gene expression. J Mol Endocrinol 27: 123-131.
3. Burset, M., Seledtsov, I.A. and Solovyev, V.V. (2000) Analysis of canonical and non-canonical splice sites in mammalian genomes. Nucleic Acids Res 8: 4364-4375.
4. Canaves, J.M. and Taylor, S.S. (2002) Classification and phylogenetic analysis of the cAMP-dependent protein kinase regulatory subunit family. J Mol Evol 54: 17-29.
5. Chen, C.Y.A. and Shyu, A.B. (1995) AU-rich elements: characterization and importance in mRNA degradation. TIBS 20: 465-469.
6. Dahle, M.K., Reinton, N., Orstavik, S., Tasken, K.A. and Tasken, K. (2001) Novel alternatively spliced mRNA (1c) of the protein kinase A RI & alpha subunit is implicated in haploid germ cell specific expression. Mol Reprod Dev 59: 11-16.
7. Dean, J.L., Sully, G., Clark, A.R. and Saklatvala, J. (2004) The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation. Cell Signal 16: 1113-1121.
8. Eisenhardt, D., Fiala, A., Braun, P., Rosenboom, H., Kress, H., Ebert, P.R. and Menzel, R. (2001) Cloning of a catalytic subunit of a cAMP-dependent protein kinase from the honeybee (Apis mellifera) and its localization in the brain. Insect Mol Biol 10: 173-181.
9. Eisenhardt, D., Friedrich, A., Stollhoff, N., Müller, U., Kress, H. and Menzel, R. (2003) The AmCREB gene is an ortholog of the mammalian CREB/CREM family of transcription factors and encodes several splice variants in the honeybee brain. Insect Mol Biol 12: 373-382.
10. Fassler, J., Landsman, D., Acharya, A., Moll, J.R., Bonovich, M. and Vinson, C. (2002) B-ZIP proteins encoded by the Drosophila genome: evaluation of potential dimerization partners. Genome Res 12: 1190-1200.
11. Fiala, A., Müller, U. and Menzel, R. (1999) Reversible downregulation of protein kinase A during olfactory learning using antisense technique impairs long-term memory formation in the honeybee, Apis mellifera. J Neurosci 19: 10125-10134.
12. Foulkes, N.S., Mellström, B., Benusiglio, E. and Sassone-Corsi, P. (1992) Developmental switch of CREM function during spermatogenesis: from antagonist to activator. Nature 355: 80-84.
13. Foulkes, N.S., Schlotter, F., Pévet, P. and Sassone-Corsi, P. (1993) Pituitary hormone FSH directs the CREM functional switch during spermatogenesis. Nature 362: 264-267.
14. Francis, S.H. and Corbin, J.D. (1999) Cyclic nucleotide-dependent protein kinases: Intracellular receptors for cAMP and cGMP. Crit Rev Clin Lab Sci 36: 275-328.
15. Friedrich, A., Thomas, U. and Muller, U. (2004) Learning at different satiation levels reveals parallel functions for the cAMP-protein kinase A cascade in formation of long-term memory. J Neurosci 24: 4460-4468.
16. Galliot, B., Welschof, M., Schuckert, O., Hoffmeister, S. and Schaller, H.C. (1995) The cAMP response element binding protein is involved in hydra regeneration. Development 121: 1205-1209.
17. Geballe, A.P. (1996) Translational control mediated by upstream AUG codons. In Translational Control (Hershey, J.W.B., Mathews, M.B. and Sonenberg, N., eds), pp. 199-244. Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
18. Gonzalez, G.A., Menzel, P., Leonard, J., Fischer, W.H. and Montminy, M.R. (1991) Characterization of motives which are critical for activity of the cyclic AMP-responsive transcription factor CREB. Mol Cell Biol 11: 1306-1312.
19. Guthrie, C.R., Skalhegg, B.S. and McKnight, G.S. (1997) Two novel brain-specific splice variants of the murine Cbeta gene of cAMP-dependent protein kinase. J Biol Chem 272: 29560-29565.
20. Hai, T. and Hartman, M.G. (2001) The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: activating transcription factor proteins and homeostasis. Gene 273: 1-11.
21. Kalderon, D. and Rubin, G.M. (1988) Isolation and characterization of Drosophila cAMP-dependent protein kinase genes. Genes Dev 2: 1539-1556.
22. Kandel, E.R. (2001) The molecular biology of memory storage: a dialogue between genes and synapses. Science 294: 1030-1038.
23. Knighton, D.R., Zheng, J.H., Ten Eyck, L.F., Ashford, V.A., Xuong, N.H., Taylor, S.S. and Sowadski, J.M. (1991) Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase. Science 253: 407-414.
24. Kozak, M. (2002) Pushing the limits of the scanning mechanism for initiation of translation. Gene 299: 1-34.
25. Laoide, B.M., Foulkes, N.S., Schlotter, F. and Sassone-Corsi, P. (1993) The functional versatility of CREM is determined by its modular structure. EMBO J 12: 1179-1191.
26. Leboulle, G. and Muller, U. (2004) Synergistic activation of insect cAMP-dependent protein kinase A (type II) by cyclic AMP and cyclic GMP. FEBS Lett 576: 216-220.
27. Li, X., Li, H.P., Amsler, K., Hyink, D., Wilson, P.D. and Burrow, C.R. (2002) PRKX, a phylogenetically and functionally distinct cAMP-dependent protein kinase, activates renal epithelial cell migration and morphogenesis. Proc Natl Acad Sci USA 99: 9260-9265.
28. Liu, F., Thompson, M.A., Wagner, S., Greenberg, M.E. and Green, M.R. (1993) Activating transcription factor-1 can mediate Ca(2+)- and cAMP-inducible transcriptional activation. J Biol Chem 268: 6714-6720.
29. Lonze, B.E. and Ginty, D.D. (2002) Function and regulation of CREB family transcription factors in the nervous system. Neuron 35: 605-623.
30. Masquilier, D., Foulkes, N.S., Mattei, M.G. and Sassone-Corsi, P. (1993) Human CREM gene: evolutionary conservation, chromosomal localization, and inducibility of the transcript. Cell Growth Differ 4: 931-937.
31. Meijer, H.A. and Thomas, A.A. (2002) Control of eukaryotic protein synthesis by upstream open reading frames in the 5′-untranslated region of an mRNA. Biochem J 367: 1-11.
32. Melendez, A., Li, W. and Kalderon, D. (1995) Activity, expression and function of a second Drosophila protein kinase A catalytic subunit gene. Genetics 141: 1507-1520.
33. Menzel, R. (2001) Searching for the memory trace in a mini-brain, the honeybee. Learn Mem 8: 53-62.
34. Orstavik, S., Reinton, N., Frengen, E., Langeland, B.T., Jahnsen, T. and Skalhegg, B.S. (2001) Identification of novel splice variants of the human catalytic subunit Cbeta of cAMP-dependent protein kinase. Eur J Biochem 268: 5066-5073.
35. Orstavik, S., Funderud, A., Hafte, T.T., Eikvar, S., Jahnsen, T. and Skalhegg, B.S. (2005) Identification and characterization of novel PKA holoenzymes in human T lymphocytes. FEBS J 272: 1559-1567.
36. Poels, J. and Vanden Broeck, J. (2004) Insect basic leucine zipper proteins and their role in cyclic AMP-dependent regulation of gene expression. Int Rev Cytol 241: 277-309.
37. Quinn, P.G. (1993) Distinct activation domains within cAMP response element-binding protein (CREB) basal and cAMP-stimulated transcription. J Biol Chem 268: 16999-17009.
38. Ruppert, S., Cole, T.J., Boshart, M., Schmid, E. and Schuetz, G. (1992) Multiple mRNA isoforms of the transcription activator protein CREB: generation by alternative splicing and specific expression in primary spermatocytes. EMBO J 11: 1503-1512.
39. Schiebel, K., Mertz, A., Winkelmann, M., Glaser, B., Schempp, W. and Rappold, G. (1997) FISH localization of the human Y-homolog of protein kinase PRKX (PRKY) to Yp11.2 and two pseudogenes to 15q26 and Xq12→q13. Cytogenet Cell Genet 76: 49-52.
40. Short, S., Manohar, C.F., Furtado, M.R., Ghadge, G.D., Wolinsky, S.M., Thimmapaya, B. and Jungmann, R.A. (1991) Nucleotide and derived amino-acid sequences of CRE-binding proteins from rat C6 glioma and HeLa cells. Nucleic Acids Res 19: 4290.
41. Smolik, S.M., Rose, R.E. and Goodman, R.H. (1992) A cyclic AMP-responsive element-binding transcriptional activator in D. melanogaster, dCREB-A, is a member of the leucine zipper family. Mol Cell Biol 12: 4123-4131.
42. Tasken, K. and Aandahl, E.M. (2004) Localized effects of cAMP mediated by distinct routes of protein kinase A. Physiol Rev 84: 137-167.
43. Taylor, S.S., Kim, C., Vigil, D., Haste, N.M., Yang, J., Wu, J. and Anand, G.S. (2005) Dynamics of signaling by PKA. Biochim Biophys Acta 1754: 25-37.
44. Usui, T., Smolik, S.M. and Goodman, R.H. (1993) Isolation of Drosophila CREB-B: a novel CRE-binding protein. DNA Cell Biol 12: 589-595.
45. Wahle, E. and Keller, W. (1992) The biochemistry of 3′-end cleavage and polyadenylation of messenger RNA precursors. Annu Rev Biochem 61: 419-440.
46. Wheelan, S.J., Church, D.M. and Ostell, J.M. (2001) Spidey: a tool for mRNA-to-genomic alignments. Genome Res 11: 1952-1957.
47. Wu, Q. and Krainer, A.R. (1999) AT-AC pre-mRNA splicing mechanisms and conservation of minor introns in voltage-gated ion channel genes. Mol Cell Bio 19: 3225-3236.
48. Yin, J.C., Wallach, J.S., Wilder, E.L., Klingensmith, J., Dang, D., Perrimon, N. et al. (1995) A Drosophila CREB/CREM homolog encodes multiple isoforms, including a cyclic AMP-dependent protein kinase-responsive transcriptional activator and antagonist. Mol Cell Biol 15: 5123-5130.
49. Zimmermann, B., Chiorini, J.A., Ma, Y., Kotin, R.M. and Herberg, F.W. (1999) PrKX is a novel catalytic subunit of the cAMP-dependent protein kinase regulated by the regulatory subunit type I. J Biol Chem 274: 5370-5378.