Impaired transport as a mechanism of resistance to thiopurines in human T-lymphoblastic leukemia cells

Nucleosides, Nucleotides and Nucleic Acids

Volumn 25, Issue 9-11, 2006, Pages 1039-1044

  Fotoohi, Alan Kambiz ^a   Lindqvist, M ^b   Peterson, C ^b   Albertioni, F ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b LINKÖPING UNIVERSITY   (Sweden)

Author keywords

6 Mercaptopurine; 6 Thioguanine; Leukemia; Resistance; Transport

Indexed keywords

6 MERCAPTOPURINE DERIVATIVE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; INOSINATE DEHYDROGENASE; MERCAPTOPURINE; THIOPURINE METHYLTRANSFERASE; TIOGUANINE;

ARTICLE; CELL LINE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; DRUG METABOLISM; DRUG TRANSPORT; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LEUKEMIA; LEUKEMIA CELL; T LYMPHOBLAST;

6-MERCAPTOPURINE; ANTIMETABOLITES, ANTINEOPLASTIC; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; IMP DEHYDROGENASE; LEUKEMIA, T-CELL, ACUTE; METHYLTRANSFERASES; THIOGUANINE; TIME FACTORS;

EID: 33750435940     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770600890848     Document Type: Article

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