A major susceptibility locus for HTLV-1 infection in childhood maps to chromosome 6q27

Human Molecular Genetics

Volumn 15, Issue 22, 2006, Pages 3306-3312

  Plancoulaine, Sabine ^a   Gessain, Antoine ^b   Tortevoye, Patricia ^b   Boland Auge, Anne ^c   Vasilescu, Alexandre ^c   Matsuda, Fumihiko ^c   Abel, Laurent ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b INSTITUT PASTEUR   (France)

^c CENTRE NATIONAL DE GÉNOTYPAGE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR6; INHIBITOR OF DIFFERENTIATION 2;

AFRICA; ARTICLE; CHILD; CHROMOSOME 2P; CHROMOSOME 6Q; CHROMOSOME MAP; CLINICAL ARTICLE; CONTROLLED STUDY; EXON; GENE LOCUS; GENETIC HETEROGENEITY; GENETIC LINKAGE; GENETIC MODEL; GENETIC SUSCEPTIBILITY; HUMAN; HUMAN T CELL LEUKEMIA VIRUS 1; INFECTION SENSITIVITY; LINKAGE ANALYSIS; ONCOVIRINAE; PEDIGREE; PRIORITY JOURNAL; SEGREGATION ANALYSIS; VIRUS INFECTION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALLELES; CHILD; CHILD, PRESCHOOL; CHROMOSOMES, HUMAN, PAIR 6; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HTLV-I INFECTIONS; HUMAN T-LYMPHOTROPIC VIRUS 1; HUMANS; INFANT; INHIBITOR OF DIFFERENTIATION PROTEIN 2; MALE; MIDDLE AGED; PEDIGREE; RECEPTORS, CHEMOKINE;

HUMAN T-LYMPHOTROPIC VIRUS 1;

EID: 33750410761     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddl406     Document Type: Article

References (47)

1. Poiesz, B.J., Ruscetti, F.W., Gazdar, A.F., Bunn, P.A., Minna, J.D. and Gallo, R.C. (1980) Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma. Proc. Natl Acad. Sci. USA, 77, 7415-7419.
2. Gessain, A., Barin, F., Vernant, J.C., Gout, O., Maurs, L., Calender, A. and de The, G. (1985) Antibodies to human T-lymphotropic virus type-I in patients with tropical spastic paraparesis. Lancet, 2, 407-410.
3. Mueller, N. and Blattner, W. (1997) Retroviruses: Human T cell lymphotropic virus. In Evans, A.S. and Kaslow, R.A. (eds), Viral Infections of Humans: Epidemiology and Control, Plenum, New York, pp. 785-814.
4. Li, H.C., Biggar, R.J., Miley, W.J., Maloney, E.M., Cranston, B., Hanchard, B. and Hisada, M. (2004) Provirus load in breast milk and risk of mother-to-child transmission of human T lymphotropic virus type I. J. Infect. Dis., 190, 1275-1278.
5. Hino, S., Sugiyama, H., Doi, H., Ishimaru, T., Yamabe, T., Tsuji, Y. and Miyamoto, T. (1987) Breaking the cycle of HTLV-I transmission via carrier mothers' milk. Lancet, 2, 158-159.
6. Ureta-Vidal, A., Angelin-Duclos, C., Tortevoye, P., Murphy, E., Lepere, J.F., Buigues, R.P., Jolly, N., Joubert, M., Carles, G., Pouliquen, J.F. et al. (1999) Mother-to-child transmission of human T-cell-leukemia/ lymphoma virus type I: Implication of high antiviral antibody titer and high proviral load in carrier mothers. Int. J. Cancer, 82, 832-836.
7. Tajima, K., Tominaga, S., Suchi, T., Kawagoe, T., Komoda, H., Hinuma, Y., Oda, T. and Fujita, K. (1982) Epidemiological analysis of the distribution of antibody to adult T-cell leukemia-virus-associated antigen: Possible horizontal transmission of adult T-cell leukemia virus. Gann, 73, 893-901.
8. Kaplan, J.E., Khabbaz, R.F., Murphy, E.L., Hermansen, S., Roberts, C., Lal, R., Heneine, W., Wright, D., Matijas, L., Thomson, R. et al. (1996) Male-to-female transmission of human T-cell lymphotropic virus types I and II: Association with viral load. The Retrovirus Epidemiology Donor Study Group. J. Acquir. Immune Defic. Syndr. Hum. Retrovirol., 12, 193-201.
9. Okochi, K., Sato, H. and Hinuma, Y. (1984) A retrospective study on transmission of adult T cell leukemia virus by blood transfusion: seroconversion in recipients. Vox Sang., 46, 245-253.
10. Murphy, E.L., Hanchard, B., Figueroa, J.P., Gibbs, W.N., Lofters, W.S., Campbell, M., Goedert, J.J. and Blattner, W.A. (1989) Modelling the risk of adult T-cell leukemia/lymphoma in persons infected with human T-lymphotropic virus type I. Int. J. Cancer, 43, 250-253.
11. Bartholomew, C., Jack, N., Edwards, J., Charles, W., Corbin, D., Cleghorn, F.R. and Blattner, W.A. (1998) HTLV-I serostatus of mothers of patients with adult T-cell leukemia and HTLV-I-associated myelopathy/ tropical spastic paraparesis. J. Hum. Virol., 1, 302-305.
12. Tajima, K., Tominaga, S., Suchi, T., Fukui, H., Komoda, H. and Hinuma, Y. (1986) HTLV-I carriers among migrants from an ATL-endemic area to ATL non- endemic metropolitan areas in Japan. Int. J. Cancer, 37, 383-387.
13. Plancoulaine, S., Buigues, R.P., Murphy, E.L., van Beveren, M., Pouliquen, J.F., Joubert, M., Remy, F., Tuppin, P., Tortevoye, P., de The, G. et al. (1998) Demographic and familial characteristics of HTLV-1 infection among an isolated, highly endemic population of African origin in French Guiana. Int. J. Cancer, 76, 331-336.
14. Plancoulaine, S., Gessain, A., Joubert, M., Tortevoye, P., Jeanne, I., Talarmin, A., de The, G. and Abel, L. (2000) Detection of a major gene predisposing to human T lymphotropic virus type I infection in children among an endemic population of African origin. J. Infect. Dis., 182, 405-412.
15. Dupuis, J. and Siegmund, D. (1999) Statistical methods for mapping quantitative trait loci from a dense set of markers. Genetics, 151, 373-386.
16. Cook, D.N., Prosser, D.M., Forster, R., Zhang, J., Kuklin, N.A., Abbondanzo, S.J., Niu, X.D., Chen, S.C., Manfra, D.J., Wiekowski, M.T. et al. (2000) CCR6 mediates dendritic cell localization, lymphocyte homeostasis, and immune responses in mucosal tissue. Immunity, 12, 495-503.
17. Varona, R., Villares, R., Carramolino, L., Goya, I., Zaballos, A., Gutierrez, J., Torres, M., Martinez, A.C. and Marquez, G. (2001) CCR6-deficient mice have impaired leukocyte homeostasis and altered contact hypersensitivity and delayed-type hypersensitivity responses. J. Clin. Invest., 107, R37-R45.
18. Rivera, R. and Murre, C. (2001) The regulation and function of the Id proteins in lymphocyte development. Oncogene, 20, 8308-8316.
19. Kim, J.K., Takeuchi, M. and Yokota, Y. (2004) Impairment of intestinal intraepithelial lymphocytes in Id2 deficient mice. Gut, 53, 480-486.
20. Morrow, M.A., Mayer, E.W., Perez, C.A., Adlam, M. and Siu, G. (1999) Overexpression of the helix-loop-helix protein Id2 blocks T cell development at multiple stages. Mol. Immunol., 36, 491-503.
21. Yokota, Y., Mansouri, A., Mori, S., Sugawara, S., Adachi, S., Nishikawa, S. and Gruss, P. (1999) Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2. Nature, 397, 702-706.
22. Barmak, K., Harhaj, E., Grant, C., Alefantis, T. and Wigdahl, B. (2003) Human T cell leukemia virus type I-induced disease: Pathways to cancer and neurodegeneration. Virology, 308, 1-12.
23. Bangham, C.R. (2000) HTLV-1 infections. J. Clin. Pathol., 53, 581-586.
24. Usuku, K., Sonoda, S., Osame, M., Yashiki, S., Takahashi, K., Matsumoto, M., Sawada, T., Tsuji, K., Tara, M. and Igata, A. (1988) HLA haplotype-linked high immune responsiveness against HTLV-I in HTLV-I-associated myelopathy: Comparison with adult T-cell leukemia/ lymphoma. Ann. Neurol., 23 (suppl.), S143-S150.
25. Yashiki, S., Fujiyoshi, T., Arima, N., Osame, M., Yoshinaga, M., Nagata, Y., Tara, M., Nomura, K., Utsunomiya, A., Hanada, S. et al. (2001) HLA-A*26, HLA-B*4002, HLA-B*4006, and HLA-B*4801 alleles predispose to adult T cell leukemia: The limited recognition of HTLV type 1 tax peptide anchor motifs and epitopes to generate anti-HTLV type 1 tax CD8(+) cytotoxic T lymphocytes. AIDS Res. Hum. Retroviruses, 17, 1047-1061.
26. Manns, A., Hanchard, B., Morgan, O.S., Wilks, R., Cranston, B., Nam, J.M., Blank, M., Kuwayama, M., Yashiki, S., Fujiyoshi, T. et al. (1998) Human leukocyte antigen class II alleles associated with human T-cell lymphotropic virus type I infection and adult T-cell leukemia/lymphoma in a Black population. J. Natl Cancer Inst., 90, 617-622.
27. Manel, N., Kim, F.J., Kinet, S., Taylor, N., Sitbon, M. and Battini, J.L. (2003) The ubiquitous glucose transporter GLUT-1 is a receptor for HTLV. Cell, 115, 449-459.
28. Coskun, A.K. and Sutton, R.E. (2005) Expression of glucose transporter 1 confers susceptibility to human T-cell leukemia virus envelope-mediated fusion. J. Virol., 79, 4150-4158.
29. Lugering, A., Floer, M., Westphal, S., Maaser, C., Spahn, T.W., Schmidt, M.A., Domschke, W., Williams, I.R. and Kucharzik, T. (2005) Absence of CCR6 inhibits CD4+ regulatory T-cell development and M-cell formation inside Peyer's patches. Am. J. Pathol., 166, 1647-1654.
30. Varona, R., Cadenas, V., Flores, J., Martinez, A.C. and Marquez, G. (2003) CCR6 has a non-redundant role in the development of inflammatory bowel disease. Eur. J. Immunol., 33, 2937-2946.
31. Kusunoki, T., Sugai, M., Katakai, T., Omatsu, Y., Iyoda, T., Inaba, K., Nakahata, T., Shimizu, A. and Yokota, Y. (2003) TH2 dominance and defective development of a CD8+ dendritic cell subset in Id2-deficient mice. J. Allergy Clin. Immunol., 111, 136-142.
32. Hacker, C., Kirsch, R.D., Ju, X.S., Hieronymus, T., Gust, T.C., Kuhl, C., Jorgas, T., Kurz, S.M., Rose-John, S., Yokota, Y. et al. (2003) Transcriptional profiling identifies Id2 function in dendritic cell development. Nat. Immunol., 4, 380-386.
33. Mira, M.T., Alcais, A., Nguyen, V.T., Moraes, M.O., Di Flumeri, C., Vu, H.T., Mai, C.P., Nguyen, T.H., Nguyen, N.B., Pham, X.K. et al. (2004) Susceptibility to leprosy is associated with PARK2 and PACRG. Nature, 427, 636-640.
34. Mathew, S., Chen, W., Murty, V.V., Benezra, R. and Chaganti, R.S. (1995) Chromosomal assignment of human ID1 and ID2 genes. Genomics, 30, 385-387.
35. Hara, E., Yamaguchi, T., Nojima, H., Ide, T., Campisi, J., Okayama, H. and Oda, K. (1994) Id-related genes encoding helix-loop-helix proteins are required for G1 progression and are repressed in senescent human fibroblasts. J. Biol. Chem., 269, 2139-2145.
36. Zaballos, A., Varona, R., Gutierrez, J., Lind, P. and Marquez, G. (1996) Molecular cloning and RNA expression of two new human chemokine receptor-like genes. Biochem. Biophys. Res. Commun., 227, 846-853.
37. Liao, F., Lee, H.H. and Farber, J.M. (1997) Cloning of STRL22, a new human gene encoding a G-protein-coupled receptor related to chemokine receptors and located on chromosome 6q27. Genomics, 40, 175-180.
38. Rozen, S. and Skaletsky, H.J. (2000) Primer3 on the WWW for general users and for biologist programmers. In Krawetz, S. and Misener, S. (eds), Bioinformatics Methods and Protocols: Methods in Molecular Biology, Humana Press, Totowa, NJ, pp. 365-386.
39. Takahashi, M., Matsuda, F., Margetic, N. and Lathrop, M. (2003) Automated identification of single nucleotide polymorphisms from sequencing data. J. Bioinform. Comput. Biol., 1, 253-265.
40. Ott, J. (1997) Genetic mapping of complex disorders. In Pawlowitzki, I.-H., Edwards, J.H. and Thompson, E.A. (eds), Genetic Mapping of Disease Genes, Academic Press, London, pp. 23-30.
41. Terwilliger, J.D. and Ott, J. (1994) Handbook of Human Genetic Linkage, Johns Hopkins University Press, Baltimore.
42. Kruglyak, L., Daly, M.J., Reeve-Daly, M.P. and Lander, E.S. (1996) Parametric and nonparametric linkage analysis: A unified multipoint approach. Am. J. Hum. Genet., 58, 1347-1363.
43. Abecasis, G.R., Cherny, S.S., Cookson, W.O. and Cardon, L.R. (2002) Merlin - rapid analysis of dense genetic maps using sparse gene flow trees. Nat. Genet., 30, 97-101.
44. Abecasis, G.R. and Wigginton, J.E. (2005) Handling marker - marker linkage disequilibrium: Pedigree analysis with clustered markers. Am. J. Hum. Genet., 77, 754-767.
45. Ott, J. (1989) Computer-simulation methods in human linkage analysis. Proc. Natl Acad. Sci. USA, 86, 4175-4178.
46. Weeks, D.E., Ott, J. and Lathrop, M. (1990) SLINK: A general simulation program for linkage analysis. Am. J. Hum. Genet., 47 (suppl.), A204.
47. Barrett, J.C., Fry, B., Maller, J. and Daly, M.J. (2005) Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics, 21, 263-265.