Towards understanding the aetiology and pathophysiology of human hypertension: Where are we now?

Journal of Human Hypertension

Volumn 20, Issue 11, 2006, Pages 833-836

  Kakar, P ^a   Lip, G Y H ^a  

^a UNIVERSITY DEPARTMENT OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN II; ANTIHYPERTENSIVE AGENT; C REACTIVE PROTEIN; ENDOTHELIN 1; GUANINE NUCLEOTIDE BINDING PROTEIN; HOMOCYSTEINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INTERLEUKIN 6; LEPTIN; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

AMINO ACID BLOOD LEVEL; ANTIINFLAMMATORY ACTIVITY; CARDIOVASCULAR RISK; DYSLIPIDEMIA; EDUCATION; ENDOTHELIAL DYSFUNCTION; ESSENTIAL HYPERTENSION; GLUCOSE INTOLERANCE; HEREDITY; HUMAN; HYPERHOMOCYSTEINEMIA; HYPERTENSION; INCOME; INFLAMMATION; LOW BIRTH WEIGHT; METABOLIC SYNDROME X; NONHUMAN; NOTE; OBESITY; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PREVALENCE; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; RISK FACTOR; SIGNAL TRANSDUCTION; SMOKING; SOCIOECONOMICS;

COMPREHENSION; ENDOTHELIUM, VASCULAR; HUMANS; HYPERTENSION;

EID: 33750373383     PISSN: 09509240     EISSN: 14765527     Source Type: Journal    
DOI: 10.1038/sj.jhh.1002082     Document Type: Note

References (39)

1. Pearce MS, O'Sullivan JJ. The relationship between birth weight and pulse pressure in children: Cross-sectional study. J Human Hypertens 2006; 20: 207-211.
2. Li C, Huang TT-K, Cruz ML, Goran MI. Birth weight, puberty, and systolic blood pressure in children and adolescents: A longitudinal analysis. J Hum Hypertens 2006; 20: 444-450.
3. Koupil I, Leon DA, Byberg L. Birth weight, hypertension and 'white coat' hypertension: Size at birth in relation to office and 24-h ambulatory blood pressure. J Hum Hypertens 2005; 19: 635-642.
4. Van Minh H, Byass P, Chuc NTK, Wall S. Gender differences in prevalence and socioeconomic determinants of hypertension: Findings from the WHO STEPs survey in a rural community of Vietnam. J Hum Hypertens 2006; 20: 109-115.
5. Geleijnse JM, Grobbee DE, Kok FJ. Impact of dietary and lifestyle factors on the prevalence of hypertension in Western populations. J Hum Hypertens 2005; 19(Suppl 3): S1-S4.
6. Gulliford Mc, Mahabir D, Rocke B. Socio economic inequality in blood pressure and its determinants: Cross sectional data from Trinidad and Tobago. J Hum Hypertens 2004; 18: 61-70.
7. Bener A, Al-Suwaidi J, Al-Jaber K, Al-Marri S. Epidemiology of hypertension and its associated risk factors in a Qatari population. J Hum Hypertens 2004; 18: 529-530.
8. Boos CJ, Lip GYH. Is hypertension an inflammatory process? Curr Pharm Des 2006; 12(13): 1623-1635.
9. Sesso HD, Buring JE, Rifai N, Blake GJ, Gaziano JM, Ridker PM et al. C-reactive protein and the risk of developing hypertension. JAMA 2003; 290: 2945-2951.
10. Boos CJ, Lip GY. Targeting the renin-angiotensin-aldosterone system in atrial fibrillation: From pathophysiology to clinical trials. J Hum Hypertens 2005; 19(11): 855-859.
11. Kazzam E, Ghurbana BA, Obineche EN, Nicholls MG. Hypertension - still an important cause of heart failure? J Hum Hypertens 2005; 19(4): 267-275.
12. Orakzai RH, Orakzai SH, Nasir K, Santos RD, Rana JS, Pimentel I et al. Association of white blood cell count with systolic blood pressure within the normotensive range. J Hum Hypertens 2006; 20: 341-347.
13. Watanabe T, Yasunari K, Nakamura M, Maeda K. Carotid artery intima-media thickness and reactive oxygen species formation by monocytes in hypertensive patients. J Hum Hypertens 2006; 20: 336-340.
14. Bautista LE, Vera LM, Arenas IA, Gamarra G. Independent association between inflammatory markers (C-reactive protein, interleukin-6, and TNF-alpha) and essential hypertension. J Hum Hypertens 2005; 19: 149-154.
15. Manabe S, Okura T, Watanabe S, Higaki J. Association between carotid haemodynamics and inflammation in patients with essential hypertension. J Hum Hypertens 2005; 19(10): 787-791.
16. Boos CJ, Lip GY. Elevated high-sensitive C-reactive protein, large arterial stiffness and atherosclerosis: A relationship between inflammation and hypertension. J Hum Hypertens 2005; 19(7): 511-513.
17. Varughese GI, Lip GY. Hypertension in patients with type-II diabetes: relation to urinary albumin excretion, endothelial function and inflammation. J Hum Hypertens 2005; 19(6): 421-424.
18. Schram MT, van Ittersum FJ, Spoelstra-de Man A, van Dijk RA, Schalkwijk CG, Ijzerman RG et al. Aggressive antihypertensive therapy based on hydrochlorothiazide, candesartan or lisinopril as initial choice in hypertensive type II diabetic individuals effects on albumin excretion, endothelial function and inflammation in a double-blind, randomized clinical trial. J Hum Hypertens 2005; 19(6): 429-437.
19. Ustundag S, Arikan E, Sen S, Esgin H, Ciftci S. The relationship between the levels of plasma total homocysteine and insulin resistance in uncomplicated mild-to-moderate primary hypertension. J Hum Hypertens 2006; 20: 379-381.
20. Mayer Jr O, Filipovsky J, Dolesjova M, Cifkova R, Simon J, Bolek L. Mild hyperhomocysteinuria is associated with increased aortic stiffness in general population. J Hum Hypertens 2006; 20(6): 267-273.
21. Schutte R, Huisman HW, Schutte AE, Malan NT. Leptin is independantly associated with systolic blood pressure, pulse pressure and arterial compliancein hypertensive African women with increased adiposity: The POWIRS study. J Hum Hypertens 2005; 19(6): 535-542.
22. Karter Y, Aydin S, Curgunlu A, Uzun H, Erturk N, Vehid S. Endothelium and angiogenesis in white coat hypertension. J Hum Hypertens 2004; 18: 809-814.
23. Boos CJ, Goon PK, Lip GY. Endothelial progenitor cells in the vascular pathophysiology of hypertension: Arterial stiffness, ageing and more. J Hum Hypertens 2006; 20(7): 475-477.
24. Tao J, Wang Y, Yang Z, Tu C, Xu M-G, Wang JM. Circulating endothelial progenitor cell deficiency contributes to impaired arterial elasticity in persons of advancing age. J Hum Hypertens 2006; 20: 490-495.
25. Volpe M, Ruilope LM, McInnes GT, Waeber B, Weber MA. Angiotensin-II receptor blockers: Benefits beyond blood pressure reduction? J Hum Hypertens 2005; 19: 331-339.
26. Neutel JM. Effect of the renin-angiotensin system on the vessel wall: using ACE inhibition to improve endothelial function. J Hum Hypertens 2004; 18: 599-606.
27. Parslow RA, Sachdev P, Salonikas C, Lux O, Jorm AF, Naidoo D. Associations between plasma antioxidants and hypertension in a community-based sample of 415 Australians aged 60-64. J Hum Hypertens 2005; 19: 219-226.
28. Tanira MO, Al Balushi KA. Genetic variations related to hypertension: A review. J Hum Hypertens 2005; 19: 7-19.
29. Caulfield M, Munroe P, Pembroke J, Samani N, Dominiczak A, Brown M, et al., MRC British Genetics of Hypertension Study. Genome-wide mapping of human loci for essential hypertension. Lancet 2003; 361(9375): 2118-2123.
30. Czarnecka D, Kawecka-Jaszcz K, Stolarz K, Olszanecka A, Dembinska-Kiec A, Kiec-Wilk B. Ambulatory blood pressure, left ventricular mass and vascular phenotypes in relation to the endothelial nitric oxide synthase gene Glu298Asp and intron 4 polymorphisms in a population-based family study. J Hum Hypertens 2005; 19(5): 413-420.
31. Cheung BM, Leung RY, Man YB, Wong LY, Lau CP. Association of essential hypertension with a microsatellite marker on chromosome 17. J Hum Hypertens 2005; 19(5): 407-411.
32. Guizar-Mendoza JM, Amador-Licona N, Flores-Martinez SE, Lopez-Cardona MG, Ahuatzin-Tremary R, Sanchez-Corona J. Association analysis of the Gln223Arg polymorphism in the human leptin receptor gene, and traits related to obesity in Mexican adolescents. J Hum Hypertens 2005; 19(5): 341-346.
33. Hoffmann IS, Tavares-Mordwinkin R, Castejon AM, Alfieri AB, Cubeddu LX. Endothelial nitric oxide synthase polymorphism, nitric oxide production, salt sensitivity and cardiovascular risk factors in Hispanics. J Hum Hypertens 2005; 19(3): 233-240.
34. Robinson MT, Wilson TW, Nicholson GA, Grell GA, Etienne C, Grim CM et al. AGT and RH blood group polymorphisms affect blood pressure and lipids in Afro-Caribbeans. J Hum Hypertens 2004; 18(5): 351-363.
35. Kuznetsova T, Staessen JA, Reineke T, Olszanecka A, Ryabikov A, Tikhonoff V, et al., European Project On Genes in Hypertension (EPOGH) Investigators. Context-dependency of the relation between left ventricular mass and AGT gene variants. J Hum Hypertens 2005; 19(2): 155-163.
36. Robinson M, Williams SM. Role of two angiotensinogen polymorphisms in blood pressure variation. J Hum Hypertens 2004; 18(12): 865-869.
37. Nakayama T, Soma M, Kanmatsuse K, Kokubun S. The microsatellite alleles on chromosome 1 associated with essential hypertension and blood pressure levels. J Hum Hypertens 2004; 18(11): 823-828.
38. Fallo F, Pilon C, Barzon L, Pistorello M, Sonino N, Veglio F et al. Retention of heterozygosity at chromosome 7p22 and 11q13 in aldosterone-producing tumours of patients with familial hyperaldosteronism not remediable by glucocorticoids. J Hum Hypertens 2004; 18(11): 829-830.
39. Nurnberger J, Opazo Saez A, Mitchell A, Buhrmann S, Wenzel RR, Siffert W et al. The T-allele of the C825T polymorphism is associated with higher arterial stiffness in young healthy males. J Hum Hypertens 2004; 18(4): 267-271.