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Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 843, Issue 2, 2006, Pages 302-309

Determination of the 4-monohydroxy metabolites of perhexiline in human plasma, urine and liver microsomes by liquid chromatography

(6) Davies, Benjamin J a,b Herbert, Megan K a Coller, Janet K b Somogyi, Andrew A b Milne, Robert W c Sallustio, Benedetta C a,b

a QUEEN ELIZABETH HOSPITAL (Australia)

b UNIVERSITY OF ADELAIDE (Australia)

c UNIVERSITY OF SOUTH AUSTRALIA (Australia)

Author keywords

HPLC; Liver microsomes; Metabolites; Perhexiline; Pharmacokinetics

Indexed keywords

BIOASSAY; FLUORESCENCE; METABOLITES; METHANOL; NEUROLOGY; PHARMACOKINETICS; REACTION KINETICS; SENSITIVITY ANALYSIS; TOXICITY;

GRADIENT ELUSION; HUMAN PLASMA; LIVER MICROSOMES; PERHEXILINE (PHX);

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

4 HYDROXYPERHEXILINE; ACETAZOLAMIDE; ACETYLSALICYLIC ACID; ALLOPURINOL; AMILORIDE; AMIODARONE; AMITRIPTYLINE; AMOXICILLIN; AMPHOTERICIN; ATENOLOL; ATORVASTATIN; AZITHROMYCIN; BETAXOLOL; BRINZOLAMIDE; BUSULFAN; CABERGOLINE; CANDESARTAN; CARBIDOPA; CARVEDILOL; CEFALEXIN; CEFOTAXIME; CEFTAZIDIME; CEFTRIAXONE; CIPROFLOXACIN; CITALOPRAM; CYTOCHROME P450 2D6; DRUG METABOLITE; PERHEXILINE; PERHEXILINE MALEATE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ACCURACY; AGED; ARTICLE; CONTROLLED STUDY; DERIVATIZATION; ELUTION; FEMALE; FLUORESCENCE; HUMAN; HUMAN TISSUE; KIDNEY CLEARANCE; KINETICS; LIQUID CHROMATOGRAPHY; LIVER; MALE; MICROSOME; PLASMA; PRIORITY JOURNAL; URINE;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; MICROSOMES, LIVER; PERHEXILINE;

EID: 33750364874 PISSN: 15700232 EISSN: None Source Type: Journal
DOI: 10.1016/j.jchromb.2006.06.020 Document Type: Article

Times cited : (9)

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