Connexin expression and gap junctional intercellular communication in human squamous cell carcinoma of the head and neck

Otolaryngology - Head and Neck Surgery

Volumn 135, Issue 5, 2006, Pages 736-743

  Frank, Douglas K ^a,b   Szymkowiak, Bozena ^a   Hughes, Cynthia A ^c  

^a Neck Cancer Molecular Biology Research Laboratory   (United States)

^b NEW YORK EYE AND EAR INFIRMARY   (United States)

^c NEW YORK UNIVERSITY COLLEGE OF DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONNEXIN 26; CONNEXIN 43; GAP JUNCTION PROTEIN; LUCIFER YELLOW;

ARTICLE; CANCER INHIBITION; CELL COMMUNICATION; CELL LINE; CELL MEMBRANE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOSOL; GAP JUNCTION; HEAD AND NECK CARCINOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA;

APOPTOSIS; BYSTANDER EFFECT; CARCINOMA, SQUAMOUS CELL; CELL COMMUNICATION; CELL COUNT; CONNEXIN 43; CONNEXINS; EPITHELIAL CELLS; FLUORESCENT ANTIBODY TECHNIQUE; GAP JUNCTIONS; HEAD AND NECK NEOPLASMS; HUMANS; MOUTH MUCOSA; TUMOR CELLS, CULTURED;

EID: 33750363225     PISSN: 01945998     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.otohns.2006.06.1242     Document Type: Article

References (26)

1. Yamasaki H. Gap junction intercellular communication and carcinogenesis. Carcinogenesis 11 (1990) 1051-1058 (Grade D)
2. Holder J.W., Elmore E., and Barrett J.C. Gap junction function and cancer. Cancer Res 53 (1993) 3475-3485 (Grade D)
3. Loewenstein W.R. Junctional intercellular communication and the control of growth. Biochim Biophys Acta 560 (1979) 1-65 (Grade D)
4. Oyamada Y., Oyamada M., Fusco A., et al. Aberrant expression, function and localization of connexins in human esophageal carcinoma cell lines with different degrees of tumorigenecity. J Cancer Res Clin Oncol 120 (1994) 445-453 (Grade D)
5. Wilgenbus K.K., Kirkpatrick C.J., Knuechel R., et al. Expression of Cx26, Cx32 and Cx 43 gap junction proteins in normal and neoplastic tissues. Int J Cancer 51 (1992) 522-529 (Grade D)
6. Huang R., Liu Y.G., Lin Y., et al. Enhanced apoptosis under low serum conditions in human glioblastoma cells by connexin 43. Mol Carcinog 32 (2001) 128-138 (Grade D)
7. Huang R., Lin Y., Wang C.C., et al. Connexin 43 suppresses human glioblastoma cell growth by down-regulation of monocyte chemotactic protein 1, as discovered using protein array technology. Cancer Res 62 (2002) 2806-2812 (Grade D)
8. Tanaka M., and Grossman H.B. Connexin 26 induces growth suppression, apoptosis and increased efficacy of doxorubicin in prostate cancer cells. Oncol Rep 11 (2004) 537-541 (Grade D)
9. Frank D.K., Frederick M.J., Liu T.J., et al. Bystander effect in the adenovirus-mediated wild-type p53 gene therapy model of human squamous cell carcinoma of the head and neck. Clin Cancer Res 4 (1998) 2521-2528 (Grade D)
10. Frank D.K., Szymkowiak B., Josifovska-Chopra O., et al. Single-cell microinjection of cytochrome C can result in gap junction-mediated apoptotic cell death of bystander cells in human squamous cell carcinoma of the head and neck. Head Neck 27 (2005) 794-800 (Grade D)
11. Azzam E.I., de Toledo S.M., Gooding T., et al. Intercellular communication is involved in the bystander regulation of gene expression in human cells exposed to very low fluences of alpha particles. Radiat Res 150 (1998) 497-504 (Grade D)
12. Azzam E.I., de Toledo S.M., and Little J.B. Direct evidence for the participation of gap junction-mediated intercellular communication in the transmission of damage signals from α-particle irradiated cells to nonirradiated cells. Proc Natl Acad Sci USA 98 (2001) 473-478 (Grade D)
13. Cusato K., Bosco A., Rozental R., et al. Gap junctions mediate bystander cell death in developing retina. J Neurosci 23 (2003) 6413-6422 (Grade D)
14. Nagar S., Smith L.E., and Morgan W.F. Characterization of a novel epigenetic effect of ionizing radiation: the death inducing effect. Cancer Res 63 (2003) 324-328 (Grade D)
15. Krutovskikh V.A., Piccoli C., and Yamasaki H. Gap junction intercellular communication propogates cell death in cancerous cells. Oncogene 21 (2002) 1989-1999 (Grade D)
16. Grossman H.B., Liebert M., Lee I.W., et al. Decreased connexin expression and intercellular communication in human bladder cancer cells. Cancer Res 54 (1994) 3062-3065 (Grade D)
17. Xu L., Schantz S.P., Edelstein D., et al. A simplified method for the routine culture of normal oral epithelial cells from upper aerodigestive tract mucosa. Methods Cell Sci 18 (1996) 31-39 (Grade D)
18. El-Fouly M.H., Trosko J.E., and Chang C.C. Scrape loading and dye transfer: a rapid technique to study gap junctional intercellular communication. Exp Cell Res 168 (1987) 422-430 (Grade D)
19. Chen Y., Huhn D., Knosel T., et al. Downregulation of connexin 26 in human lung cancer is related to promoter methylation. Int J Cancer 113 (2005) 14-21 (Grade D)
20. Tan L.W., Bianco T., and Dobrovic A. Variable promoter region CpG island methylation of the putative tumor suppressor gene connexin 26 in breast cancer. Cacinogenesis 23 (2002) 231-236 (Grade D)
21. Huang R.P., Fan Y., Hossain M.Z., et al. Reversion of the neoplastic phenotype of human glioblastoma cells by connexin 43 (cx43). Cancer Res 58 (1998) 5089-5096 (Grade D)
22. Peebles K.A., Duncan M.W., Ruch R.J., et al. Proteomic analysis of a mouse lung epithelial cell line whose tumorigenicity has been abrogated by transfection with the gap junction structural gene for connexin 43, Gja1. Carcinogenesis 24 (2003) 651-657 (Grade D)
23. Al Moustafa A.E., Alaoui-Jamali M.A., Batist G., et al. Identification of genes associated with head and neck carcinogenesis by cDNA microarray comparison between matched primary normal epithelial and squamous carcinoma cells. Oncogene 21 (2002) 2634-2640 (Grade D)
24. Broghammer M., Leistenschneider P., Baus-Loncar M., et al. Rediced expression of connexin 31.1 in larynx cancer is not caused by GJB5 mutations. Cancer Lett 214 (2004) 225-229 (Grade D)
25. Schneider B., Teschner M., Sudermann T., et al. Expression of gap junction proteins (connexin 26, 30, 32, 43) in normal mucosa, hyperkeratosis and carcinoma of the human larynx. ORL J Otorhinolaryngol Relat Spec 64 (2002) 324-329 (Grade D)
26. Villaret D.B., Wang T., Dillon D., et al. Identification of genes overexpressed in head and neck squamous cell carcinoma using a combination of complementary DNA subtraction and microarray analysis. Laryngoscope 110 (2000) 374-381 (Grade D)