Increasing expression of fascin in renal cell carcinoma associated with clinicopathological parameters of aggressiveness

Histology and Histopathology

Volumn 21, Issue 10-12, 2006, Pages 1287-1293

  Jin, J S ^a   Yu, C P ^a   Sun, G H ^a   Lin, Y F ^a   Chiang, H ^b   Chao, T K ^a   Tsai, W C ^a   Sheu, L F ^a  

^a TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^b Taipei Institute of Pathology   (Taiwan)

Author keywords

Clear cell type; Fascin; Granular cell differentiation; Renal cell carcinoma; Sarcomatoid differentiation

Indexed keywords

FASCIN; ACTIN BINDING PROTEIN; CARRIER PROTEIN;

ADVANCED CANCER; ARTICLE; CANCER GRADING; CANCER STAGING; CELL DIFFERENTIATION; CELL MEMBRANE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOPLASM; GRANULAR CELL; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; KIDNEY CARCINOMA; KIDNEY TUBULE; MAJOR CLINICAL STUDY; METASTASIS POTENTIAL; PROTEIN EXPRESSION; TISSUE MICROARRAY; DISEASE COURSE; GENE EXPRESSION REGULATION; GENETICS; HOSPITALIZATION; MICROARRAY ANALYSIS; MORTALITY; PATHOLOGY; PROGNOSIS;

CARCINOMA, RENAL CELL; CARRIER PROTEINS; DISEASE PROGRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; MICROARRAY ANALYSIS; MICROFILAMENT PROTEINS; NEOPLASM STAGING; PROGNOSIS; SEVERITY OF ILLNESS INDEX;

EID: 33750353401     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Atkins M.B., Regan M. and McDermott D. (2004). Update on the role of interleukin 2 and other cytokines in the treatment of patients with stage IV renal carcinoma. Clin. Cancer Res. 10, 6342S-4346S.
2. Aznavoorian S., Murphy A.N., Stetler-Stevenson W.G. and Liotta L.A. (1993). Molecular aspects of tumor cell invasion and metastasis. Cancer 71, 1368-1383.
3. Bonsib S.M., Gibson D., Mhoon M. and Greene G.F. (2000). Renal sinus involvement in renal cell carcinomas. Am. J. Surg. Pathol. 24, 451-458.
4. Flanigan R.C. (2004). Debulking nephrectomy in metastatic renal cancer. Clin. Cancer Res. 10, 6335S-6341S.
5. Goncharuk V.N., Ross J.S. and Carlson J.A. (2002). Actin-binding protein fascin expression in skin neoplasia. J. Cutan. Pathol. 29, 430-438.
6. Grothey A., Hashizume R., Sahin A.A. and McCrea P.D. (2000). Fascin, an actin-bundling protein associated with cell motility, is upregulated in hormone receptor negative breast cancer. Br. J. Cancer 83, 870-873.
7. Hidalgo A., Pina P., Guerrero G., Lazos M. and Salcedo M. (2003). A simple method for the construction of a small format tissue arrays. J. Clin. Pathol. 56, 144-146.
8. Hu W., McCrea P.D., Deavers M., Kavanagh J.J., Kudelka A.P. and Verschraegen C.F. (2000). Increased expression of fascin, motility associated protein, in cell cultures derived from ovarian cancer and in borderline and carcinomatous ovarian tumors. Clin. Exp. Metastasis 18, 83-88.
9. Jawhari A.U., Buda A., Jenkins M., Shehzad K., Sarraf C., Noda M., Farthing M.J., Pignatelli M. and Adams J.C. (2003). Fascin, an actin-bundling protein, modulates colonic epithelial cell invasiveness and differentiation in vitro. Am. J. Pathol. 162, 69-80.
10. Jin J.S., Hsieh D.S., Loh S.H., Chen A., Yao C.W. and Yen C.Y. (2006). Increasing expression of serine protease matritase in ovary tumors: tissue microarray analysis of immunostaining score with clinicopathological parameters. Modern Pathol. 19, 447-452.
11. Kerbel R.S. (1990). Growth dominance of the metastatic cancer cell: cellular and molecular aspects. Adv. Cancer Res. 55, 87-132.
12. Kerbel R.S., Waghorne C., Korczak B., Lagarde A. and Breitman M.L. (1988). Clonal dominance of primary tumours by metastatic cells: genetic analysis and biological implications. Cancer Surv. 7, 597-629.
13. Kureishy N., Sapountzi V., Prag S., Anilkumar N. and Adams J.C. (2002). Fascins, and their roles in cell structure and function. BioEssays 24, 350-361.
14. Lam J.S., Belldegrun A.S. and Figlin R.A. (2004). Tissue array-based predictions of pathobiology, prognosis and response to treatment for renal cell carcinoma therapy. Clin. Cancer Res. 10, 6304s-6309s.
15. Lauffenburger D.A. and Horwitz A.F. (1996). Cell migration: A physically integrated molecular process. Cell 84, 359-369.
16. Partin A.W., Shoeniger J.S., Mohler L.L. and Coffey D.S. (1989). Fourier analysis of cell motility: correlation of motility with metastatic potentials. Proc. Natl. Acad. Sci. USA 86, 1254-1258.
17. Pelosi G., Pasini F., Fraggetta F., Pastorino U., Iannucci A., Maisonneuve P., Arrigoni G., De Manzoni G., Bresaola E. and Viale G. (2003a). Independent value of fascin immunoreactivity for predicting lymph node metastases in typical and atypical pulmonary carcinoids. Lung Cancer 42, 203-213.
18. Pelosi G., Pastorino U., Pasini F., Maissoneuve P., Fraggetta F., Iannucci A., Sonzogni A., De Manzoni G., Terzi A., Durante E., Bresaola E., Pezzella F. and Viale G. (2003b). Independent prognostic value of fascin immunoreactivity in stage I nonsmall cell lung cancer. Br. J. Cancer 88, 537-547.
19. Rosen D.G., Huang X., Deavers M.T., Malpica A., Silva E.G. and Lium J. (2004). Validation of tissue microarray technique in ovarian carcinoma. Modern Pathol. 17, 790-797.
20. Rosenthal E.L., Shreenivas S., Peters G.E., Grizzle W.E., Desmond R. and Gladson C.L. (2003). Expression of extracellular matrix metalloproteinase inducer in laryngeal squamous cell carcinoma. Laryngoscope 113, 1406-1410.
21. Su Z.Z., Austin V.N., Zimmer S.G. and Fisher P.B. (1993). Defining the critical gene expression changes associated with expression and suppression of the tumorigenic and metastatic phenotype in Ha-ras-transformed cloned rat embryo fibroblast cells. Oncogene 8, 1211-1219.
22. Sweeney P., Wood C.G., Pisters L.L., Slaton J.W., Vaporciyan A., Munsell M., Carpenter S., Putnam J., Swisher S.G., Walsh G., Swanson D. and Dinney C.P. (2003). Surgical management of renal cell carcinoma associated with complex inferior vena caval thrombi. Urolo. Oncology 21, 327-333.
23. Yamashiro S., Yamakita Y., Ono S. and Matsumura F. (1998). Fascin, an actin-bundling protein, induces membrane protrusions and increases cell motility of epithelial cells. Mol. Biol. Cell 9, 993-1006.
24. Yoder B.J., Tso, E., Skacel M., Pettay J., Tarr S., Budd T., Tubbs R.R. Adams J.C. and Hicks D.G. (2005). The expression of fascin, an actin-bundling motility protein, correlates with hormone receptor-negative breast cancer and a more aggressive clinical course. Clin. Cancer Res. 11, 186-192.