Sequential and simultaneous statistical optimization by dynamic design of experiment for peptide overexpression in recombinant Escherichia coli

Applied Biochemistry and Biotechnology

Volumn 135, Issue 1, 2006, Pages 59-80

  Lee, Kwang Min ^a   Rhee, Chang Hoon ^a   Kang, Choong Kyung ^b   Kim, Jung Hoe ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^b KoBioTech Co Ltd   (South Korea)

Author keywords

Anti HIV peptide; Dynamic experimental design; Statistical optimization

Indexed keywords

ESCHERICHIA COLI; EXPERIMENTS; FERMENTATION; GLUCOSE; OPTIMIZATION; STATISTICAL METHODS;

ANTI-HIV PEPTIDE; DYNAMIC EXPERIMENTAL DESIGN; STATISTICAL OPTIMIZATION;

PROTEINS;

CELL PROTEIN; GLUCOSE; ISOPROPYL BETA THIOGALACTOSIDE; MAGNESIUM SULFATE; PYRANOSIDE; RECOMBINANT PROTEIN; TRACE ELEMENT; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; ESCHERICHIA COLI; EXPERIMENTAL DESIGN; FERMENTATION; METHODOLOGY; NONHUMAN; OPTICAL DENSITY; STATISTICAL ANALYSIS;

ANTI-HIV AGENTS; BIOREACTORS; BIOTECHNOLOGY; CULTURE MEDIA; DRUG DESIGN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; FERMENTATION; GENE EXPRESSION REGULATION, BACTERIAL; MAGNESIUM SULFATE; PEPTIDES; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; REGRESSION ANALYSIS; TIME FACTORS;

ESCHERICHIA COLI;

EID: 33750352421     PISSN: 02732289     EISSN: None     Source Type: Journal    
DOI: 10.1385/ABAB:135:1:59     Document Type: Article

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