A validated liquid chromatographic-tandem mass spectroscopy method for the quantification of abiraterone acetate and abiraterone in human plasma

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 843, Issue 2, 2006, Pages 262-267

  Martins, Vanessa ^a   Asad, Yasmin ^a   Wilsher, Nicola ^a   Raynaud, Florence ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

Abiraterone; Liquid chromatography tandem mass spectrometry; Prostate cancer; Validation

Indexed keywords

ACETONITRILE; BIOASSAY; ESTERS; MASS SPECTROMETRY; PHARMACOKINETICS; SOLVENT EXTRACTION; TUMORS;

ABIRATRONE ACETATE; PROSTATE CANCER; QUANTIFICATION;

LIQUID CHROMATOGRAPHY;

2 PROPANOL; ABIRATERONE; ABIRATERONE ACETATE; ACETONITRILE; AMMONIUM ACETATE; ANTIANDROGEN; CATION; POLYMER; UNCLASSIFIED DRUG;

ANDROGEN SYNTHESIS; ARTICLE; BIOASSAY; BLOOD ANALYSIS; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; HUMAN; LINEAR SYSTEM; LIQUID CHROMATOGRAPHY; METABOLITE; PHYSICAL PHASE; PLASMA; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SEPARATION TECHNIQUE; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS; VARIANCE;

ANDROSTENOLS; CHROMATOGRAPHY, LIQUID; DRUG STABILITY; HUMANS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 33750351934     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2006.06.010     Document Type: Article

References (13)

1. Hellerstedt B.A., and Pienta K.J. CA Cancer J. Clin. 52 (2002) 154
2. Denis L., and Murphy G.P. Cancer 72 (1993) 3888
3. Denmeade S.R., and Isaacs J.T. Nat. Rev. 2 (2002) 389
4. Scher H.I., and Sawyers C.L. J. Clin. Oncol. 23 (2005) 8253
5. Leroux F. Curr. Med. Chem. 14 (2005) 1623
6. Pont A., Williams P.L., Loose D.S., Feldman D., Reitz R.E., Bochra C., and Stevens D.S. Ann. Intern. Med. 97 (1982) 370
7. Pont A., Williams P.L., Azhar S., Reitz R.E., Bochra C., Smith E.R., and Stevens D.A. Arch. Intern. Med. 142 (1982) 2137
8. Loose D.S., Kan P.B., Hirst M.A., Marcus R.A., and Feldman D. J. Clin. Invest. 71 (1983) 1495
9. Rowlands M.G., Barrie S.E., Chan F., Houghton J., Jarman M., McCague R., and Potter G.A. J. Med. Chem. 38 (1995) 4191
10. Barrie S.E., Potter G.A., Goddard P.M., Haynes B.P., Dowsett M., and Jarman M. J. Steroid Biochem. Mol. Biol. 50 (1994) 267
11. Potter G.A., Barrie S.E., Jarman M., and Rowlands M.G. J. Med. Chem. 38 (1995) 2463
12. O'Donnell A., Judson I., Dowsett M., Raynaud F., Dearnaley D., Mason M., Harland S., Robbins A., Halbert G., Nutley B., and Jarman M. Br. J. Cancer 90 (2004) 2317
13. Guidance for industry: Bioanalytical method validation. US Department of Health and Human Services, Food and Drug Administration, Centre for Veterinary Medicine, May 2001.