Collaboration of RON and Epidermal Growth Factor Receptor in Human Bladder Carcinogenesis

Journal of Urology

Volumn 176, Issue 5, 2006, Pages 2262-2267

  Hsu, Pei Yin ^a   Liu, Hsiao Sheng ^a   Cheng, Hong Lin ^a   Tzai, Tzong Shin ^a   Guo, How Ran ^a   Ho, Chung Liang ^a   Chow, Nan Haw ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

bladder; bladder neoplasms; epidermal growth factor; receptor

Indexed keywords

4 (3 BROMOANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; PROTEIN; PROTEIN RON; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ADULT; AGED; APOPTOSIS; ARTICLE; BLADDER CANCER; BLADDER CARCINOGENESIS; CANCER CELL CULTURE; CANCER INVASION; CANCER RECURRENCE; CANCER STAGING; CANCER SURVIVAL; CELL MIGRATION; CELL TRANSFORMATION; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MAJOR CLINICAL STUDY; MALE; MITOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; STATISTICAL SIGNIFICANCE; WOUND HEALING;

CARCINOMA, TRANSITIONAL CELL; CELL LINE, TUMOR; HUMANS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, EPIDERMAL GROWTH FACTOR; URINARY BLADDER NEOPLASMS;

EID: 33750345267     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.juro.2006.07.048     Document Type: Article

References (20)

1. Gschwind A., Zwick E., Prenzel N., Leserer M., and Ullrich A. Cell communication networks: epidermal growth factor receptor transactivation as the paradigm for interreceptor signal transmission. Oncogene 20 (2001) 1594
2. Heldin C.H. Dimerization of cell surface receptors in signal transduction. Cell 80 (1995) 213
3. Hackel P.O., Zwick E., Prenzel N., and Ullrich A. Epidermal growth factor receptors: critical mediators of multiple receptor pathways. Curr Opin Cell Biol 11 (1999) 184
4. Ronsin C., Muscatelli F., Mattei M.G., and Breathnach R. A novel putative receptor protein tyrosine kinase of the met family. Oncogene 8 (1993) 1195
5. Gaudino G., Follenzi A., Naldini L., Collesi C., Santoro M., Gallo K.A., et al. RON is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSP. EMBO J 13 (1994) 3524
6. Leonard E.J., and Skeel A. A serum protein that stimulates macrophage movement, chemotaxis and spreading. Exp Cell Res 102 (1976) 434
7. Rampino T., Collesi C., Gregorini M., Maggior M., Soccio G., Guallini P., et al. Macrophage-stimulating protein is produced by tubular cells and activates mesangial cells. J Am Soc Nephrol 13 (2002) 649
8. Wang M.H., Wang D., and Chen Y.Q. Oncogenic and invasive potential of human macrophages-stimulating protein receptor, the RON receptor tyrosine kinase. Carcinogenesis 23 (2003) 1291
9. Maggiora P., Marchio S., Stella M.C., Giai M., Belfiore A., De Bortoli M., et al. Overexpression of the RON gene is human breast carcinoma. Oncogene 16 (1998) 2927
10. Zhou Y.Q., He C., Chen Y.Q., Wang D., and Wang M.H. Altered expression of the RON receptor tyrosine kinase in primary human colorectal adenocarcinomas: generation of different splicing variants and their oncogenic potential. Oncogene 22 (2003) 186
11. Maggiora P., Lorenzato A., Francchioli S., Costa B., Castagnaro M., Arisio R., et al. The RON and MET oncogenes are co-expression in human ovarian carcinomas and cooperate in activating invasiveness. Exp Cell Res 288 (2003) 382
12. Cheng H.L., Liu H.S., Lin Y.J., Chen H.H., Hsu P.Y., Change T.Y., et al. Co-expression of RON and MET is a prognostic indicator for patients with transitional-cell carcinoma of the bladder. Br J Cancer 92 (2005) 1906
13. Follenzi A., Bakovic S., Gual P., Stella M.C., Longati P., and Comoglio P.M. Cross-talk between the proto-oncogenes Met and Ron. Oncogene 19 (2000) 3041
14. Wang M.H., Dlugosz A.A., Sun Y., Suda T., Skeel A., and Leonard E.J. Macrophage- stimulating protein induces proliferation and migration of murine keratinocytes. Exp Cell Res 226 (1996) 39
15. Peace B.E., Hill K.J., Degen S.J.F., and Waltz S.E. Cross-talk between the receptor tyrosine kinases Ron and epidermal growth factor receptor. Exp Cell Res 289 (2003) 317
16. Chow N.H., Lin Y.J., Cheng H.L., Tzai T.S., Ho C.L., Chang T.Y., et al. The significance of macrophage stimulating protein (MSP)/RON signaling pathway in the progression of human bladder cancer. Proc Am Assoc Cancer Res 44 (2003) 397 abstract
17. Hsu P.Y., Liu H.S., Ho C.L., and Chow N.H. Cross-talk between RON receptor and epidermal growth factor receptor in human epithelial carcinogenesis. Proc Am Assoc Cancer Res 46 (2005) 5275 abstract
18. Zwick E., Hackel P.O., Prenzel N., and Ullrich A. The EGF receptor as central transducer of heterologous signalling systems. Trends Pharmacol Sci 20 (1999) 408
19. Ahmad T., Farnie G., Bundred N.J., and Anderson N.G. The mitogenic action of insulin-like growth factor I in normal human mammary epithelial cells requires the epidermal growth factor receptor tyrosine kinase. J Biol Chem 279 (2004) 1713
20. Penengo L., Rubin C., Yarden Y., and Gaudino G. c0-Cbl is a critical modulator of the RON tyrosine kinase receptor. Oncogene 22 (2003) 2669