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Volumn 21, Issue 6, 2006, Pages 613-617

Cyclooxygenase-2 inhibitors and cardiovascular risk

Author keywords

Cardiovascular risk; Cyclooxygenase 2 inhibitors; Nonsteroidal anti inflammatory drugs; NSAIDs

Indexed keywords

CELECOXIB; CYCLOOXYGENASE 2 INHIBITOR; ETORICOXIB; IBUPROFEN; LUMIRACOXIB; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PLACEBO; ROFECOXIB; VALDECOXIB;

EID: 33750326220     PISSN: 02684705     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.hco.0000245740.85829.4f     Document Type: Review
Times cited : (24)

References (29)
  • 1
    • 0033551847 scopus 로고    scopus 로고
    • Arachidonic acid oxygenation by COX-1 and COX-2: Mechanisms of catalysis and inhibition
    • Marnett LJ, Rowlinson SW, Goodwin DC, et al. Arachidonic acid oxygenation by COX-1 and COX-2: mechanisms of catalysis and inhibition. J Biol Chem 1999; 274:22903-22906.
    • (1999) J Biol Chem , vol.274 , pp. 22903-22906
    • Marnett, L.J.1    Rowlinson, S.W.2    Goodwin, D.C.3
  • 2
    • 23244445988 scopus 로고    scopus 로고
    • Cyclooxygenase Inhibition and Cardiovascular Risk
    • Antman EM, DeMets D, Loscalzo J. Cyclooxygenase Inhibition and Cardiovascular Risk. Circulation 2005; 112:759-770. This is an excellent recent review on cardiovascular risk associated with coxibs.
    • (2005) Circulation , vol.112 , pp. 759-770
    • Antman, E.M.1    DeMets, D.2    Loscalzo, J.3
  • 3
    • 0008664413 scopus 로고    scopus 로고
    • The eicosanoids: Prostaglandins, thromboxanes, leukotrienes, and related compounds
    • Katzung BG, editor. New York, NY: Lange Medical Books/McGraw-Hill
    • Foegh M, Ramwell P. The eicosanoids: prostaglandins, thromboxanes, leukotrienes, and related compounds. In: Katzung BG, editor. Basic and Clinical Pharmacology. 9th ed. New York, NY: Lange Medical Books/McGraw-Hill; 2004.
    • (2004) Basic and Clinical Pharmacology. 9th Ed.
    • Foegh, M.1    Ramwell, P.2
  • 4
    • 0035833502 scopus 로고    scopus 로고
    • The coxibs, selective inhibitors of cyclooxygenase-2
    • FitzGerald GA, Patrono C. The coxibs, selective inhibitors of cyclooxygenase-2. N Engl J Med 2001; 345:433-442.
    • (2001) N Engl J Med , vol.345 , pp. 433-442
    • FitzGerald, G.A.1    Patrono, C.2
  • 5
    • 6044274282 scopus 로고    scopus 로고
    • Coxibs and cardiovascular disease
    • Fitzgerald GA. Coxibs and cardiovascular disease. N Engl J Med 2004; 351:1709-1711.
    • (2004) N Engl J Med , vol.351 , pp. 1709-1711
    • Fitzgerald, G.A.1
  • 6
    • 0033524421 scopus 로고    scopus 로고
    • Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: The human pharmacology of a selective inhibitor of COX-2
    • McAdam BF, Catella-Lawson F, Mardini IA, et al. Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2. Proc Natl Acad Sci U S A 1999; 96:272-277.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 272-277
    • McAdam, B.F.1    Catella-Lawson, F.2    Mardini, I.A.3
  • 7
    • 3543044381 scopus 로고    scopus 로고
    • Relationship between COX-2 specific inhibitors and hypertension
    • Solomon DH, Schneeweiss S, Levin R, Avorn J. Relationship between COX-2 specific inhibitors and hypertension. Hypertension 2004; 44:140-145.
    • (2004) Hypertension , vol.44 , pp. 140-145
    • Solomon, D.H.1    Schneeweiss, S.2    Levin, R.3    Avorn, J.4
  • 8
    • 0036830135 scopus 로고    scopus 로고
    • Effects of celecoxib and rofecoxib on blood pressure and edema in patients > or = 65 years of age with systemic hypertension and osteoarthritis
    • SUCCESS-VII Investigators
    • Whelton A, White WB, Bello AE, et al., SUCCESS-VII Investigators. Effects of celecoxib and rofecoxib on blood pressure and edema in patients > or = 65 years of age with systemic hypertension and osteoarthritis. Am J Cardiol 2002; 90:959-963.
    • (2002) Am J Cardiol , vol.90 , pp. 959-963
    • Whelton, A.1    White, W.B.2    Bello, A.E.3
  • 9
    • 19944432721 scopus 로고    scopus 로고
    • The effects of cyclooxygenase-2 inhibitors and nonsteroidal anti-inflammatory therapy on 24-h blood pressure in patients with hypertension, osteoarthritis, and type 2 diabetes mellitus
    • Celecoxib Rofecoxib Efficacy and Safety in Comorbidities Evaluation Trial (CRESCENT) Investigators
    • Sowers JR, White WB, Pitt B, et al., Celecoxib Rofecoxib Efficacy and Safety in Comorbidities Evaluation Trial (CRESCENT) Investigators. The effects of cyclooxygenase-2 inhibitors and nonsteroidal anti-inflammatory therapy on 24-h blood pressure in patients with hypertension, osteoarthritis, and type 2 diabetes mellitus. Arch Intern Med 2005; 165:161-168.
    • (2005) Arch Intern Med , vol.165 , pp. 161-168
    • Sowers, J.R.1    White, W.B.2    Pitt, B.3
  • 10
    • 1442313005 scopus 로고    scopus 로고
    • Effects of COX inhibition on blood pressure and kidney function in ACE inhibitor-treated blacks and hispanics
    • Izhar M, Alausa T, Folker A, et al. Effects of COX inhibition on blood pressure and kidney function in ACE inhibitor-treated blacks and hispanics. Hypertension 2004; 43:573-577.
    • (2004) Hypertension , vol.43 , pp. 573-577
    • Izhar, M.1    Alausa, T.2    Folker, A.3
  • 11
    • 0036237083 scopus 로고    scopus 로고
    • Effects of celecoxib on ambulatory blood pressure in hypertensive patients on ACE inhibitors
    • White WB, Kent J, Taylor A, et al. Effects of celecoxib on ambulatory blood pressure in hypertensive patients on ACE inhibitors. Hypertension 2002; 39:929-934.
    • (2002) Hypertension , vol.39 , pp. 929-934
    • White, W.B.1    Kent, J.2    Taylor, A.3
  • 12
    • 2442493150 scopus 로고    scopus 로고
    • Relationship between selective cyclooxygenase-2 inhibitors and acute myocardial infarction in older adults
    • Solomon DH, Schneeweiss S, Glynn RJ, et al. Relationship between selective cyclooxygenase-2 inhibitors and acute myocardial infarction in older adults. Circulation 2004; 109:2068-2073.
    • (2004) Circulation , vol.109 , pp. 2068-2073
    • Solomon, D.H.1    Schneeweiss, S.2    Glynn, R.J.3
  • 13
    • 12344291466 scopus 로고    scopus 로고
    • Patients exposed to rofecoxib and celecoxib have different odds of nonfatal myocardial infarction
    • Kimmel SE, Berlin JA, Reilly M, et al. Patients exposed to rofecoxib and celecoxib have different odds of nonfatal myocardial infarction. Ann Intern Med 2005; 142:157-164.
    • (2005) Ann Intern Med , vol.142 , pp. 157-164
    • Kimmel, S.E.1    Berlin, J.A.2    Reilly, M.3
  • 14
    • 13744263350 scopus 로고    scopus 로고
    • Summary for patients in
    • Summary for patients in Ann Intern Med 2005; 142:I21.
    • (2005) Ann Intern Med , vol.142
  • 15
    • 13444263619 scopus 로고    scopus 로고
    • Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclo-oxygenase 2 selective and nonselective nonsteroidal anti-inflammatory drugs: Nested case-control study
    • Graham DJ, Campen D, Hui R, et al. Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclo-oxygenase 2 selective and nonselective nonsteroidal anti-inflammatory drugs: nested case-control study. Lancet 2005; 365:475-481. This describes an important observational study of cardiovascular risk associated with coxibs.
    • (2005) Lancet , vol.365 , pp. 475-481
    • Graham, D.J.1    Campen, D.2    Hui, R.3
  • 16
    • 0034707105 scopus 로고    scopus 로고
    • Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis
    • VIGOR Study Group. VIGOR Study Group
    • Bombardier C, Laine L, Reicin A, et al., VIGOR Study Group. Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group. N Engl J Med 2000; 343:1520-1528.
    • (2000) N Engl J Med , vol.343 , pp. 1520-1528
    • Bombardier, C.1    Laine, L.2    Reicin, A.3
  • 17
    • 31344470641 scopus 로고    scopus 로고
    • Expression of concern: Bombardier et al. "Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis"
    • Curfman GD, Morrissey S, Drazen JM. Expression of concern: Bombardier et al. "Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis". N Engl J Med 2006; 343:1520-1528.
    • (2006) N Engl J Med , vol.343 , pp. 1520-1528
    • Curfman, G.D.1    Morrissey, S.2    Drazen, J.M.3
  • 19
    • 4344578073 scopus 로고    scopus 로고
    • Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), cardiovascular outcomes: Randomised controlled trial
    • TARGET Study Group
    • Farkouh ME, Kirshner H, Harrington RA, et al., TARGET Study Group. Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), cardiovascular outcomes: randomised controlled trial. Lancet 2004; 364:675-684.
    • (2004) Lancet , vol.364 , pp. 675-684
    • Farkouh, M.E.1    Kirshner, H.2    Harrington, R.A.3
  • 20
    • 33645748723 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory drugs, acetaminophen, and the risk of cardiovascular events
    • Chan AT, Manson JE, Albert CM, et al. Nonsteroidal antiinflammatory drugs, acetaminophen, and the risk of cardiovascular events. Circulation 2006; 113:1578-1587. This observational study implicated traditional NSAIDs in cardiovascular risk in a large cohort of women.
    • (2006) Circulation , vol.113 , pp. 1578-1587
    • Chan, A.T.1    Manson, J.E.2    Albert, C.M.3
  • 21
    • 19744380776 scopus 로고    scopus 로고
    • Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial
    • Adenomatous Polyp Prevention on Vioxx (APPROVE) Trial Investigators. Erratum in N Engl J Med 2006; 355:221
    • Bresalier RS, Sandler RS, Quan H, et al., Adenomatous Polyp Prevention on Vioxx (APPROVE) Trial Investigators. Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial. N Engl J Med 2005; 352:1092-102. Erratum in N Engl J Med 2006; 355:221. This is a report of the APPROVE trial which was stopped early and led to the withdrawal of rofecoxib.
    • (2005) N Engl J Med , vol.352 , pp. 1092-1102
    • Bresalier, R.S.1    Sandler, R.S.2    Quan, H.3
  • 22
    • 17744418769 scopus 로고    scopus 로고
    • The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis
    • Steinbach G, Lynch PM, Phillips RK, et al. The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. N Engl J Med 2000; 342:1946-1952.
    • (2000) N Engl J Med , vol.342 , pp. 1946-1952
    • Steinbach, G.1    Lynch, P.M.2    Phillips, R.K.3
  • 23
    • 33745929924 scopus 로고    scopus 로고
    • Time-to-event analyses for long-term treatments - The APPROVE trial
    • Lagakos SW. Time-to-event analyses for long-term treatments - the APPROVE trial. N Engl J Med 2006; 355:113-117.
    • (2006) N Engl J Med , vol.355 , pp. 113-117
    • Lagakos, S.W.1
  • 24
    • 14944371100 scopus 로고    scopus 로고
    • Complications of the COX-2 inhibitors parecoxib and valdecoxib after cardiac surgery
    • Nussmeier NA, Whelton AA, Brown MT, et al. Complications of the COX-2 inhibitors parecoxib and valdecoxib after cardiac surgery. N Engl J Med 2005; 352:1081-1091.
    • (2005) N Engl J Med , vol.352 , pp. 1081-1091
    • Nussmeier, N.A.1    Whelton, A.A.2    Brown, M.T.3
  • 25
    • 20144365496 scopus 로고    scopus 로고
    • Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention
    • Adenoma Prevention with Celecoxib (APC) Study Investigators
    • Solomon SD, McMurray JJ, Pfeffer MA, et al., Adenoma Prevention with Celecoxib (APC) Study Investigators. Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention. N Engl J Med 2005; 352:1071-1080. This is a report of the cardiovascular risk associated with two doses of celecoxib in a randomized placebo controlled trial. This was the first placebo-controlled data demonstrating an increased cardiovascular risk with celecoxib.
    • (2005) N Engl J Med , vol.352 , pp. 1071-1080
    • Solomon, S.D.1    McMurray, J.J.2    Pfeffer, M.A.3
  • 26
    • 31844439935 scopus 로고    scopus 로고
    • FDA Advisory Committee on Cox-2 Inhibitors and NSAIDs. 16-18 February 2005. Gaithersburg: [Accessed: 16 August 2006]
    • Levin B. Celecoxib in adenoma prevention: The PreSAP Trial. FDA Advisory Committee on Cox-2 Inhibitors and NSAIDs. 16-18 February 2005. Gaithersburg: FDA. http://www.fda.gov/ohrms/dockets/ac/05/slides/2005-4090S1_09_FDA-Levin.PPT. [Accessed: 16 August 2006]
    • Celecoxib in Adenoma Prevention: The PreSAP Trial
    • Levin, B.1
  • 27
    • 33646182855 scopus 로고    scopus 로고
    • Use of first- And second-generation cyclooxygenase-2-selective nonsteroidal antiinflammatory drugs and risk of acute myocardial infarction
    • Andersohn F, Suissa S, Garbe E. Use of first- and second-generation cyclooxygenase-2-selective nonsteroidal antiinflammatory drugs and risk of acute myocardial infarction. Circulation 2006; 113:1950-1957.
    • (2006) Circulation , vol.113 , pp. 1950-1957
    • Andersohn, F.1    Suissa, S.2    Garbe, E.3
  • 28
    • 33748196958 scopus 로고    scopus 로고
    • Celecoxib for the prevention of sporadic colorectal adenomas
    • Bertagnolli MM, Eagle CJ, Zauber AG, et al. Celecoxib for the prevention of sporadic colorectal adenomas. N Engl J Med 2006; 355:873-884.
    • (2006) N Engl J Med , vol.355 , pp. 873-884
    • Bertagnolli, M.M.1    Eagle, C.J.2    Zauber, A.G.3
  • 29
    • 33748180713 scopus 로고    scopus 로고
    • Celecoxib for the prevention of colorectal adenomatous polyps
    • Arber N, Eagle CJ, Spicak J, et al. Celecoxib for the prevention of colorectal adenomatous polyps. N Engl J Med 2006; 355:885-995.
    • (2006) N Engl J Med , vol.355 , pp. 885-995
    • Arber, N.1    Eagle, C.J.2    Spicak, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.