Adjuvant-induced joint inflammation causes very rapid transcription of β-preprotachykinin and α-CGRP genes in innervating sensory ganglia

Journal of Neurochemistry

Volumn 77, Issue 2, 2001, Pages 372-382

  Bulling, Duncan G S ^a,b   Kelly, David ^b   Bond, Susan ^b   McQueen, Daniel S ^b   Seckl, Jonathan R ^a  

^a WESTERN GENERAL HOSPITAL   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Adjuvant; CGRP; Dorsal root ganglia; Inflammation; Preprotachcykinin; Rat

Indexed keywords

BETA PREPROTACHYKININ A; CALCITONIN GENE RELATED PEPTIDE RECEPTOR; MESSENGER RNA; NEUROPEPTIDE; SUBSTANCE P; TACHYKININ; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; ARTICLE; CONTROLLED STUDY; ELECTRIC ACTIVITY; HYPERALGESIA; INTRON; MALE; MONARTHRITIS; NERVE CELL; NEUROGENIC INFLAMMATION; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RAT; SENSORY GANGLION; SENSORY NERVE; SPINAL GANGLION;

ANIMALS; ARTHRITIS, EXPERIMENTAL; CALCITONIN GENE-RELATED PEPTIDE; CELL SIZE; CYCLOHEXIMIDE; FREUND'S ADJUVANT; GANGLIA, SPINAL; GENE EXPRESSION REGULATION; IN SITU HYBRIDIZATION; INJECTIONS; MALE; NEURONS, AFFERENT; PRESSURE; PROTEIN PRECURSORS; PROTEIN SYNTHESIS INHIBITORS; RADIOIMMUNOASSAY; RATS; RATS, WISTAR; REFLEX; RNA, MESSENGER; SCIATIC NERVE; SUBSTANCE P; SYNAPTIC TRANSMISSION; TACHYKININS; TARSUS, ANIMAL; TIME FACTORS; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 0035048769     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2001.00175.x     Document Type: Article

References (55)

1. Effects of surgical denervation on substance P and calcitonin gene-related peptide in adjuvant arthritis
2. Stimulation by nerve growth factor of neuropeptide synthesis in the adult rat in vivo: Bilateral response to unilateral intraplantar injections
3. 2 and cicaprost on the discharge of articular sensory receptors in vitro
4. Effects of 5-hydoxytryptamine on discharge of vagal mucosal afferent fibres from the upper gastrointestinal tract of the ferret
5. Sensory neuropeptides in the skin
6. A limited arthritic model for chronic pain in the rat
7. Kinetics of reaction between insulin and insulin-binding antibody
8. Structure, expression, and some regulatory mechanisms of the rat preprotachykinin gene encoding substance P, neurokinin A, Neuropeptide K and Neuropeptide gamma
9. Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurones following C fibre stimulation
10. Increased expression of preprotachykinin, calcitonin gene-related peptide, but not vasoactive intestinal peptide messenger RNA in dorsal root ganglia during the development of adjuvant monoarthritis
11. A. discrete adjuvant-induced monoarthritis in the rat - Effects of adjuvant dose
12. Local-anesthesia prevents acute inflammatory changes in neuropeptide messenger-RNA expression in rat dorsal-root ganglia
13. Induction of transcription factor AP2 messenger-RNA expression in rat primary afferent neurones during acute-inflammation
14. Radioimmunoassay: An overview
15. The influence of joint afferent discharge on locomotion, proprioception and activity in conscious cats
16. Cutaneous hyperalgesia induced by peripheral injection of interleukin-1β in the rat
17. Plasticity in the synthesis and storage of substance P and calcitonin gene-related peptide in primary afferent neurones during peripheral inflammation
18. Modulation of carrageenan-induced hind paw edema by substance
19. Asymmetrical rheumatoid arthritis after poliomyelitis
20. Specific temporal and spatial distribution of Jun, Fos and Krox-24 proteins in spinal neurones following noxious transynaptic stimulation
21. Nitric oxide evokes pain in humans on intracutaneous injection
22. Local effector functions of capsaicin-sensitive sensory nerve endings: Involvement of tachykinins, calcitonin gene-related peptide and other neuropeptides
23. Enhancement of dynorphin gene-expression in spinal-cord following experimental inflammation - Stimulus specificity, behavioral parameters and opioid receptor-binding
24. The regulation of protein transport to the nucleus by phosphorylation
25. Primary sensory neurones of the rat showing calcitonin gene-related peptide immunoreactivity and their relation to substance P-, somatostatin-, galanin-, vasoactive intestinal polypeptide- and cholecystokinin-immuno-reactive ganglion cells
26. Coexpression of preprotachykinin-a, alpha-calcitonin gene-related peptide, somatostatin, and neurotrophin receptor family messenger-RNAs in rat dorsal-root ganglion neurones
27. The neural basis of perception and movement
28. Calcitonin gene-related peptide increases in the dorsal root ganglia of adjuvant arthritic rat
29. Specific neurokinin receptors mediate plasma extravasation in the rat knee joint
30. Effects of interactions of naturally-occurring neuropeptides on blood flow in the rat knee joint
31. Nerve growth-factor contributes to the up-regulation of growth-associated protein-43 and preprotachykinin-a messenger-RNAs in primary sensory neurones following peripheral inflammation
32. Contribution of sensory afferents and sympathetic efferents to joint injury in experimental arthritis
33. The formalin-induced expression of tachykinin peptide and neurokinin receptor messenger RNAs in rat sensory ganglia and spinal cord is modulated by opiate preadministration
34. Nitric oxide (NO) and nociceptive processing in the spinal cord
35. Excitatory and inhibitory amino-acids and peptide-induced responses in acutely isolated rat spinal dorsal horn neurones
36. The role of spinal neurokinin-2 receptors in the processing of nociceptive information from the joint and in the generation and maintenance of inflammation-evoked hyperexcitability of dorsal horn neurones in the rat
37. Inflammatory pain hypersensitivity mediated by phenotypic switch in myelinated primary sensory neurons
38. Dynorphin expression and Fos-like immunoreactivity following inflammation induced hyperalgesia are colocalized in spinal cord neurones
39. Calcitonin gene-related peptide promotes mechanical nociception by potentiating release of substance P from the spinal dorsal horn in rats
40. Neurotransmitter functions of mammalian tachykinins
41. Effect of substance-P and somatostatin on migration of polymorphonuclear (PMN) cells-in vitro
42. Substance-P modulates glutamate-induced currents in acutely isolated rat spinal dorsal horn neurones
43. Calcitonin gene-related peptide (Cgrp) activates human neutrophils - Inhibition by chemotactic peptide antagonist bocmlp
44. Contribution of interleukin-1-beta to the inflammation-induced increase in nerve growth-factor levels and inflammatory hyperalgesia
45. Release of immunoreactive substance P in the spinal cord during development of acute arthritis in the knee joint of the cat: A study with antibody microprobes
46. Plasticity of calcitonin gene related peptide neurotransmission in the spinal cord during peripheral inflammation
47. Calcitonin gene-related peptide coexists with substance-p in capsaicin sensitive neurones and sensory ganglia of the rat
48. Psychophysical studies of the itch sensation itchy skin ("allokenesis") produced by intracutaneous injection of histamine
49. Differential roles of neurokinin 1 and neurokinin 2 receptors in the development and maintenance of heat hyperalgesia induced by acute inflammation
50. Protons selectively induce lasting excitation and sensitization to mechanical stimulation of nocieptors in rat skin, in vitro
51. Time-dependent changes in Bolton-Hunter-labeled I-125 substance-P binding in rat spinal-cord following unilateral adjuvant-induced peripheral inflammation
52. Unilateral rheumatoid arthritis following hemiplegia
53. Neuropeptide expression in rat dorsal-root ganglion-cells and spinal-cord after peripheral-nerve injury with special reference to galanin
54. The pathophysiology of chronic pain - Increased sensitivity to low threshold Aβ-fibre inputs
55. Neuropeptides promote neutrophil adherence to endothelial cell monolayers