메뉴 건너뛰기




Volumn 20, Issue 11, 2006, Pages 1967-1977

Identification of Notch target genes in uncommitted T-cell progenitors: No direct induction of a T-cell specific gene program

Author keywords

[No Author keywords available]

Indexed keywords

NOTCH1 RECEPTOR; PROTEIN DELTEX 1; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR E2A; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HES 1; TRANSCRIPTION FACTOR HOXA5; TRANSCRIPTION FACTOR NRARP; TRANSCRIPTION FACTOR TCFL5; UNCLASSIFIED DRUG;

EID: 33750323404     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/sj.leu.2404396     Document Type: Article
Times cited : (49)

References (61)
  • 3
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: Cell fate control and signal integration in development
    • Artavanis-Tsakonas S, Rand MD, Lake RJ. Notch signaling: Cell fate control and signal integration in development. Science 1999; 284: 770-776.
    • (1999) Science , vol.284 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 4
    • 0029583607 scopus 로고
    • Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H)
    • Tamura K, Taniguchi Y, Minoguchi S, Sakai T, Tun T, Furukawa T et al. Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H). Curr Biol 1995; 5: 1416-1423.
    • (1995) Curr Biol , vol.5 , pp. 1416-1423
    • Tamura, K.1    Taniguchi, Y.2    Minoguchi, S.3    Sakai, T.4    Tun, T.5    Furukawa, T.6
  • 5
    • 0037380018 scopus 로고    scopus 로고
    • Notch and lymphopoiesis: A view from the microenvironment
    • Parreira L, Neves H, Simoes S. Notch and lymphopoiesis: A view from the microenvironment. Semin Immunol 2003; 15: 81-89.
    • (2003) Semin Immunol , vol.15 , pp. 81-89
    • Parreira, L.1    Neves, H.2    Simoes, S.3
  • 6
    • 0037310525 scopus 로고    scopus 로고
    • Entry into the thymic microenvironment triggers Notch activation in the earliest migrant T cell progenitors
    • Harman BC, Jenkinson EJ, Anderson G. Entry into the thymic microenvironment triggers Notch activation in the earliest migrant T cell progenitors. J Immunol 2003; 170: 1299-1303.
    • (2003) J Immunol , vol.170 , pp. 1299-1303
    • Harman, B.C.1    Jenkinson, E.J.2    Anderson, G.3
  • 7
    • 22344445528 scopus 로고    scopus 로고
    • New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling
    • Dik WA, Pike-Overzet K, Weerkamp F, de Ridder D, de Haas EF, Baert MR et al. New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling. J Exp Med 2005; 201: 1715-1723.
    • (2005) J Exp Med , vol.201 , pp. 1715-1723
    • Dik, W.A.1    Pike-Overzet, K.2    Weerkamp, F.3    de Ridder, D.4    de Haas, E.F.5    Baert, M.R.6
  • 8
    • 33645731202 scopus 로고    scopus 로고
    • The human thymus contains multipotent progenitors with T/B-lymphoid, myeloid and erythroid lineage potential
    • Weerkamp F, Baert MR, Brugman MH, Dik WA, de Haas EF, Visser TP et al. The human thymus contains multipotent progenitors with T/B-lymphoid, myeloid and erythroid lineage potential. Blood 2006; 107: 3131-3137.
    • (2006) Blood , vol.107 , pp. 3131-3137
    • Weerkamp, F.1    Baert, M.R.2    Brugman, M.H.3    Dik, W.A.4    de Haas, E.F.5    Visser, T.P.6
  • 9
    • 0033136717 scopus 로고    scopus 로고
    • Deficient T cell fate specification in mice with an induced inactivation of Notch1
    • Radtke F, Wilson A, Stark G, Bauer M, van Meerwijk J, MacDonald HR et al. Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity 1999; 10: 547-558.
    • (1999) Immunity , vol.10 , pp. 547-558
    • Radtke, F.1    Wilson, A.2    Stark, G.3    Bauer, M.4    van Meerwijk, J.5    MacDonald, H.R.6
  • 10
    • 0035477668 scopus 로고    scopus 로고
    • Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus
    • Wilson A, MacDonald HR, Radtke F. Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus. J Exp Med 2001; 194: 1003-1012.
    • (2001) J Exp Med , vol.194 , pp. 1003-1012
    • Wilson, A.1    MacDonald, H.R.2    Radtke, F.3
  • 11
    • 20244389684 scopus 로고    scopus 로고
    • Notch1 expression in early lymphopoiesis influences B vs T lineage determination
    • Pui JC, Allman D, Xu L, DeRocco S, Karnell FG, Bakkour S et al. Notch1 expression in early lymphopoiesis influences B vs T lineage determination. Immunity 1999; 11: 299-308.
    • (1999) Immunity , vol.11 , pp. 299-308
    • Pui, J.C.1    Allman, D.2    Xu, L.3    DeRocco, S.4    Karnell, F.G.5    Bakkour, S.6
  • 12
    • 0037105544 scopus 로고    scopus 로고
    • Ectopic expression of Delta4 impairs hematopoietic development and leads to lymphoproliferative disease
    • Dorsch M, Zheng G, Yowe D, Rao P, Wang Y, Shen Q et al. Ectopic expression of Delta4 impairs hematopoietic development and leads to lymphoproliferative disease. Blood 2002; 100: 2046-2055.
    • (2002) Blood , vol.100 , pp. 2046-2055
    • Dorsch, M.1    Zheng, G.2    Yowe, D.3    Rao, P.4    Wang, Y.5    Shen, Q.6
  • 13
    • 0035476891 scopus 로고    scopus 로고
    • Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation
    • Jaleco AC, Neves H, Hooijberg E, Gameiro P, Clode N, Haury M et al. Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation. J Exp Med 2001; 194: 991-1002.
    • (2001) J Exp Med , vol.194 , pp. 991-1002
    • Jaleco, A.C.1    Neves, H.2    Hooijberg, E.3    Gameiro, P.4    Clode, N.5    Haury, M.6
  • 14
    • 13544262340 scopus 로고    scopus 로고
    • Induction of T-cell development from human cord blood hematopoietic stem cells by Delta-like 1 in vitro
    • La Motte-Mohs RN, Herer E, Zuniga-Pflucker JC. Induction of T-cell development from human cord blood hematopoietic stem cells by Delta-like 1 in vitro. Blood 2005; 105: 1431-1439.
    • (2005) Blood , vol.105 , pp. 1431-1439
    • La Motte-Mohs, R.N.1    Herer, E.2    Zuniga-Pflucker, J.C.3
  • 15
    • 13544250491 scopus 로고    scopus 로고
    • Notch ligands Delta 1 and Jagged1 transmit distinct signals to T-cell precursors
    • Lehar SM, Dooley J, Farr AG, Bevan MJ. Notch ligands Delta 1 and Jagged1 transmit distinct signals to T-cell precursors. Blood 2005; 105: 1440-1447.
    • (2005) Blood , vol.105 , pp. 1440-1447
    • Lehar, S.M.1    Dooley, J.2    Farr, A.G.3    Bevan, M.J.4
  • 16
    • 0036916440 scopus 로고    scopus 로고
    • Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro
    • Schmitt TM, Zuniga-Pflucker JC. Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro. Immunity 2002; 17: 749-756.
    • (2002) Immunity , vol.17 , pp. 749-756
    • Schmitt, T.M.1    Zuniga-Pflucker, J.C.2
  • 18
    • 33745197598 scopus 로고    scopus 로고
    • Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia
    • Weerkamp F, van Dongen JJ, Staal FJ. Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia. Leukemia 2006; 20: 1197-1205.
    • (2006) Leukemia , vol.20 , pp. 1197-1205
    • Weerkamp, F.1    van Dongen, J.J.2    Staal, F.J.3
  • 21
    • 0037198653 scopus 로고    scopus 로고
    • Overexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterations
    • Kawamata S, Du C, Li K, Lavau C. Overexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterations. Oncogene 2002; 21: 3855-3863.
    • (2002) Oncogene , vol.21 , pp. 3855-3863
    • Kawamata, S.1    Du, C.2    Li, K.3    Lavau, C.4
  • 24
    • 0033681301 scopus 로고    scopus 로고
    • Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes
    • Deftos ML, Huang E, Ojala EW, Forbush KA, Bevan MJ. Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes. Immunity 2000; 13: 73-84.
    • (2000) Immunity , vol.13 , pp. 73-84
    • Deftos, M.L.1    Huang, E.2    Ojala, E.W.3    Forbush, K.A.4    Bevan, M.J.5
  • 25
    • 0036467663 scopus 로고    scopus 로고
    • Direct induction of T lymphocyte-specific gene expression by the mammalian Notch signaling pathway
    • Reizis B, Leder P. Direct induction of T lymphocyte-specific gene expression by the mammalian Notch signaling pathway. Genes Dev 2002; 16: 295-300.
    • (2002) Genes Dev , vol.16 , pp. 295-300
    • Reizis, B.1    Leder, P.2
  • 26
    • 0036070308 scopus 로고    scopus 로고
    • Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes
    • Wolfer A, Wilson A, Nemir M, MacDonald HR, Radtke F. Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes. Immunity 2002; 16: 869-879.
    • (2002) Immunity , vol.16 , pp. 869-879
    • Wolfer, A.1    Wilson, A.2    Nemir, M.3    MacDonald, H.R.4    Radtke, F.5
  • 27
    • 4644265888 scopus 로고    scopus 로고
    • Analysis of Notch1 function by in vitro T cell differentiation of Pax5 mutant lymphoid progenitors
    • Hoflinger S, Kesavan K, Fuxa M, Hutter C, Heavey B, Radtke F et al. Analysis of Notch1 function by in vitro T cell differentiation of Pax5 mutant lymphoid progenitors. J Immunol 2004; 173: 3935-3944.
    • (2004) J Immunol , vol.173 , pp. 3935-3944
    • Hoflinger, S.1    Kesavan, K.2    Fuxa, M.3    Hutter, C.4    Heavey, B.5    Radtke, F.6
  • 28
    • 0031451172 scopus 로고    scopus 로고
    • The LIN-12/Notch signaling pathway and its regulation
    • Kimble J, Simpson P. The LIN-12/Notch signaling pathway and its regulation. Annu Rev Cell Dev Biol 1997; 13: 333-361.
    • (1997) Annu Rev Cell Dev Biol , vol.13 , pp. 333-361
    • Kimble, J.1    Simpson, P.2
  • 30
    • 0032442040 scopus 로고    scopus 로고
    • Correlating notch signaling with thymocyte maturation
    • Deftos ML, He YW, Ojala EW, Bevan MJ. Correlating notch signaling with thymocyte maturation. Immunity 1998; 9: 777-786.
    • (1998) Immunity , vol.9 , pp. 777-786
    • Deftos, M.L.1    He, Y.W.2    Ojala, E.W.3    Bevan, M.J.4
  • 31
    • 0034902568 scopus 로고    scopus 로고
    • Induction of cyclin D1 transcription and CDK2 activity by Notch(ic): Implication for cell cycle disruption in transformation by Notch(ic)
    • Ronchini C, Capobianco AJ. Induction of cyclin D1 transcription and CDK2 activity by Notch(ic): Implication for cell cycle disruption in transformation by Notch(ic). Mol Cell Biol 2001; 21: 5925-5934.
    • (2001) Mol Cell Biol , vol.21 , pp. 5925-5934
    • Ronchini, C.1    Capobianco, A.J.2
  • 32
    • 17844384528 scopus 로고    scopus 로고
    • Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation
    • Rangarajan A, Talora C, Okuyama R, Nicolas M, Mammucari C, Oh H et al. Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO J 2001; 20: 3427-3436.
    • (2001) EMBO J , vol.20 , pp. 3427-3436
    • Rangarajan, A.1    Talora, C.2    Okuyama, R.3    Nicolas, M.4    Mammucari, C.5    Oh, H.6
  • 34
    • 0032904239 scopus 로고    scopus 로고
    • Notch1-induced delay of human hematopoietic progenitor cell differentiation is associated with altered cell cycle kinetics
    • Carlesso N, Aster JC, Sklar J, Scadden DT. Notch1-induced delay of human hematopoietic progenitor cell differentiation is associated with altered cell cycle kinetics. Blood 1999; 93: 838-848.
    • (1999) Blood , vol.93 , pp. 838-848
    • Carlesso, N.1    Aster, J.C.2    Sklar, J.3    Scadden, D.T.4
  • 35
    • 1642536445 scopus 로고    scopus 로고
    • Wnt target genes identified by DNA microarrays in immature CD34+ thymocytes regulate proliferation and cell adhesion
    • Staal FJ, Weerkamp F, Baert MR, van den Burg CM, van Noort M, de Haas EF et al. Wnt target genes identified by DNA microarrays in immature CD34+ thymocytes regulate proliferation and cell adhesion. J Immunol 2004; 172: 1099-1108.
    • (2004) J Immunol , vol.172 , pp. 1099-1108
    • Staal, F.J.1    Weerkamp, F.2    Baert, M.R.3    van den Burg, C.M.4    van Noort, M.5    de Haas, E.F.6
  • 36
    • 0027517719 scopus 로고
    • Specification of axial identity in the mouse: Role of the Hoxa-5 (Hox1.3) gene
    • Jeannotte L, Lemieux M, Charron J, Poirier F, Robertson EJ. Specification of axial identity in the mouse: Role of the Hoxa-5 (Hox1.3) gene. Genes Dev 1993; 7: 2085-2096.
    • (1993) Genes Dev , vol.7 , pp. 2085-2096
    • Jeannotte, L.1    Lemieux, M.2    Charron, J.3    Poirier, F.4    Robertson, E.J.5
  • 39
    • 22144487402 scopus 로고    scopus 로고
    • Notch signaling controls the generation and differentiation of early T lineage progenitors
    • Sambandam A, Maillard I, Zediak VP, Xu L, Gerstein RM, Aster JC et al. Notch signaling controls the generation and differentiation of early T lineage progenitors. Nat Immunol 2005; 6: 663-670.
    • (2005) Nat Immunol , vol.6 , pp. 663-670
    • Sambandam, A.1    Maillard, I.2    Zediak, V.P.3    Xu, L.4    Gerstein, R.M.5    Aster, J.C.6
  • 40
    • 4344572135 scopus 로고    scopus 로고
    • Maintenance of T cell specification and differentiation requires recurrent notch receptor-ligand interactions
    • Schmitt TM, Ciofani M, Petrie HT, Zuniga-Pflucker JC. Maintenance of T cell specification and differentiation requires recurrent notch receptor-ligand interactions. J Exp Med 2004; 200: 469-479.
    • (2004) J Exp Med , vol.200 , pp. 469-479
    • Schmitt, T.M.1    Ciofani, M.2    Petrie, H.T.3    Zuniga-Pflucker, J.C.4
  • 41
    • 0029788072 scopus 로고    scopus 로고
    • Involvement of transcription factors TCF-1 and GATA-3 in the initiation of the earliest step of T cell development in the thymus
    • Hattori N, Kawamoto H, Fujimoto S, Kuno K, Katsura Y. Involvement of transcription factors TCF-1 and GATA-3 in the initiation of the earliest step of T cell development in the thymus. J Exp Med 1996; 184: 1137-1147.
    • (1996) J Exp Med , vol.184 , pp. 1137-1147
    • Hattori, N.1    Kawamoto, H.2    Fujimoto, S.3    Kuno, K.4    Katsura, Y.5
  • 42
    • 0038040548 scopus 로고    scopus 로고
    • Homeobox gene expression profile in human hematopoietic multipotent stem cells and T-cell progenitors: Implications for human T-cell development
    • Taghon T, Thys K, De Smedt M, Weerkamp F, Staal FJ, Plum J et al. Homeobox gene expression profile in human hematopoietic multipotent stem cells and T-cell progenitors: Implications for human T-cell development. Leukemia 2003; 17: 1157-1163.
    • (2003) Leukemia , vol.17 , pp. 1157-1163
    • Taghon, T.1    Thys, K.2    De Smedt, M.3    Weerkamp, F.4    Staal, F.J.5    Plum, J.6
  • 44
    • 0031663757 scopus 로고    scopus 로고
    • Cloning of TCFL5 encoding a novel human basic helix-loop-helix motif protein that is specifically expressed in primary spermatocytes at the pachytene stage
    • Maruyama O, Nishimori H, Katagiri T, Miki Y, Ueno A, Nakamura Y. Cloning of TCFL5 encoding a novel human basic helix-loop-helix motif protein that is specifically expressed in primary spermatocytes at the pachytene stage. Cytogenet Cell Genet 1998; 82: 41-45.
    • (1998) Cytogenet Cell Genet , vol.82 , pp. 41-45
    • Maruyama, O.1    Nishimori, H.2    Katagiri, T.3    Miki, Y.4    Ueno, A.5    Nakamura, Y.6
  • 46
    • 1942498907 scopus 로고    scopus 로고
    • The Notch target genes Hey1 and Hey2 are required for embryonic vascular development
    • Fischer A, Schumacher N, Maier M, Sendtner M, Gessler M. The Notch target genes Hey1 and Hey2 are required for embryonic vascular development. Genes Dev 2004; 18: 901-911.
    • (2004) Genes Dev , vol.18 , pp. 901-911
    • Fischer, A.1    Schumacher, N.2    Maier, M.3    Sendtner, M.4    Gessler, M.5
  • 47
    • 0037216703 scopus 로고    scopus 로고
    • Regulation of Notch1 and DII4 by vascular endothelial growth factor in arterial endothelial cells: Implications for modulating arteriogenesis and angiogenesis
    • Liu ZJ, Shirakawa T, Li Y, Soma A, Oka M, Dotto GP et al. Regulation of Notch1 and DII4 by vascular endothelial growth factor in arterial endothelial cells: Implications for modulating arteriogenesis and angiogenesis. Mol Cell Biol 2003; 23: 14-25.
    • (2003) Mol Cell Biol , vol.23 , pp. 14-25
    • Liu, Z.J.1    Shirakawa, T.2    Li, Y.3    Soma, A.4    Oka, M.5    Dotto, G.P.6
  • 50
    • 0030942488 scopus 로고    scopus 로고
    • Mice bearing a targeted interruption of the homeobox gene HOXA9 have defects in myeloid, erythroid, and lymphoid hematopoiesis
    • Lawrence HJ, Helgason CD, Sauvageau G, Fong S, Izon DJ, Humphries RK et al. Mice bearing a targeted interruption of the homeobox gene HOXA9 have defects in myeloid, erythroid, and lymphoid hematopoiesis. Blood 1997; 89: 1922-1930.
    • (1997) Blood , vol.89 , pp. 1922-1930
    • Lawrence, H.J.1    Helgason, C.D.2    Sauvageau, G.3    Fong, S.4    Izon, D.J.5    Humphries, R.K.6
  • 51
    • 0032528516 scopus 로고    scopus 로고
    • Loss of function of the homeobox gene Hoxa-9 perturbs early T-cell development and induces apoptosis in primitive thymocytes
    • Izon DJ, Rozenfeld S, Fong ST, Komuves L, Largman C, Lawrence HJ. Loss of function of the homeobox gene Hoxa-9 perturbs early T-cell development and induces apoptosis in primitive thymocytes. Blood 1998; 92: 383-393.
    • (1998) Blood , vol.92 , pp. 383-393
    • Izon, D.J.1    Rozenfeld, S.2    Fong, S.T.3    Komuves, L.4    Largman, C.5    Lawrence, H.J.6
  • 52
    • 0037082446 scopus 로고    scopus 로고
    • HOX-A10 regulates hematopoietic lineage commitment: Evidence for a monocyte-specific transcription factor
    • Taghon T, Stolz F, De Smedt M, Cnockaert M, Verhasselt B, Plum J et al. HOX-A10 regulates hematopoietic lineage commitment: Evidence for a monocyte-specific transcription factor. Blood 2002; 99: 1197-1204.
    • (2002) Blood , vol.99 , pp. 1197-1204
    • Taghon, T.1    Stolz, F.2    De Smedt, M.3    Cnockaert, M.4    Verhasselt, B.5    Plum, J.6
  • 53
    • 0032733668 scopus 로고    scopus 로고
    • Loss of Hoxa5 gene function in mice perturbs intestinal maturation
    • Aubin J, Chailler P, Menard D, Jeannotte L. Loss of Hoxa5 gene function in mice perturbs intestinal maturation. Am J Physiol 1999; 277: C965-C973.
    • (1999) Am J Physiol , vol.277
    • Aubin, J.1    Chailler, P.2    Menard, D.3    Jeannotte, L.4
  • 54
    • 17444420743 scopus 로고    scopus 로고
    • Delayed, asynchronous, and reversible T-lineage specification induced by Notch/Delta signaling
    • Taghon TN, David ES, Zuniga-Pflucker JC, Rothenberg EV. Delayed, asynchronous, and reversible T-lineage specification induced by Notch/ Delta signaling. Genes Dev 2005; 19: 965-978.
    • (2005) Genes Dev , vol.19 , pp. 965-978
    • Taghon, T.N.1    David, E.S.2    Zuniga-Pflucker, J.C.3    Rothenberg, E.V.4
  • 55
    • 0041428109 scopus 로고    scopus 로고
    • Surface expression of Notch1 on thymocytes: Correlation with the double-negative to double-positive transition
    • Huang EY, Gallegos AM, Richards SM, Lehar SM, Bevan MJ. Surface expression of Notch1 on thymocytes: Correlation with the double-negative to double-positive transition. J Immunol 2003; 171: 2296-2304.
    • (2003) J Immunol , vol.171 , pp. 2296-2304
    • Huang, E.Y.1    Gallegos, A.M.2    Richards, S.M.3    Lehar, S.M.4    Bevan, M.J.5
  • 56
    • 22044457152 scopus 로고    scopus 로고
    • HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL)
    • Soulier J, Clappier E, Cayuela JM, Regnault A, Garcia-Peydro M, Dombret H et al. HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL). Blood 2005; 106: 274-286.
    • (2005) Blood , vol.106 , pp. 274-286
    • Soulier, J.1    Clappier, E.2    Cayuela, J.M.3    Regnault, A.4    Garcia-Peydro, M.5    Dombret, H.6
  • 59
    • 10244224027 scopus 로고    scopus 로고
    • Molecular characterization of early human T/NK and B-lymphoid progenitor cells in umbilical cord blood
    • Haddad R, Guardiola P, Izac B, Thibault C, Radich J, Delezoide AL et al. Molecular characterization of early human T/NK and B-lymphoid progenitor cells in umbilical cord blood. Blood 2004; 104: 3918-3926.
    • (2004) Blood , vol.104 , pp. 3918-3926
    • Haddad, R.1    Guardiola, P.2    Izac, B.3    Thibault, C.4    Radich, J.5    Delezoide, A.L.6
  • 60
    • 33749059386 scopus 로고    scopus 로고
    • Effects of Delta1 and Jagged1 on early human hematopoiesis: Correlation with expression of notch signaling-related genes in CD34+ cells
    • Neves H, Weerkamp F, Gomes AC, Naber BA, Gameiro P, Becker JD et al. Effects of Delta1 and Jagged1 on early human hematopoiesis: Correlation with expression of notch signaling-related genes in CD34+ cells. Stem Cells 2006; 24: 1328-1337.
    • (2006) Stem Cells , vol.24 , pp. 1328-1337
    • Neves, H.1    Weerkamp, F.2    Gomes, A.C.3    Naber, B.A.4    Gameiro, P.5    Becker, J.D.6
  • 61
    • 33644772155 scopus 로고    scopus 로고
    • Wnt signaling in the thymus is regulated by differential expression of intracellular signaling molecules
    • Weerkamp F, Baert MR, Naber BA, Koster EE, de Haas EF, Atkuri KR et al. Wnt signaling in the thymus is regulated by differential expression of intracellular signaling molecules. Proc Natl Acad Sci USA 2006; 103: 3322-3326.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 3322-3326
    • Weerkamp, F.1    Baert, M.R.2    Naber, B.A.3    Koster, E.E.4    de Haas, E.F.5    Atkuri, K.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.