Morphologic Blooming in Breast MRI as a Characterization of Margin for Discriminating Benign from Malignant Lesions

Academic Radiology

Volumn 13, Issue 11, 2006, Pages 1344-1354

  Penn, Alan ^a   Thompson, Scott ^a   Brem, Rachel ^b   Lehman, Constance ^c   Weatherall, Paul ^d   Schnall, Mitchell ^e   Newstead, Gillian ^f   Conant, Emily ^e   Ascher, Susan ^g   Morris, Elizabeth ^h   Pisano, Etta ⁱ  

^a Penn Diagnostics   (United States)

^b GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^f UNIVERSITY OF CHICAGO   (United States)

^g GEORGETOWN UNIVERSITY HOSPITAL   (United States)

^h MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

ⁱ UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

blooming; Breast; CAD (or computer aided detection); cancer; kinetics; morphology; MRI

Indexed keywords

ADULT; ANALYTICAL PARAMETERS; ARTICLE; AUTOMATION; BENIGN TUMOR; BREAST CANCER; BREAST TUMOR; CANCER DIAGNOSIS; CLINICAL EFFECTIVENESS; COMPUTER ASSISTED DIAGNOSIS; CONTROLLED STUDY; DIFFERENTIAL DIAGNOSIS; EVALUATION; FALSE POSITIVE RESULT; FEMALE; HUMAN; KINETICS; MAJOR CLINICAL STUDY; MORPHOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PRIORITY JOURNAL; RADIODIAGNOSIS; RADIOLOGIST; SENSITIVITY ANALYSIS; TIME; TUMOR BIOPSY;

ADULT; ARTIFICIAL INTELLIGENCE; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CARCINOMA, LOBULAR; CARCINOMA, MEDULLARY; CASE-CONTROL STUDIES; CONTRAST MEDIA; FALSE POSITIVE REACTIONS; FEMALE; FOLLOW-UP STUDIES; GADOLINIUM DTPA; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MIDDLE AGED; NEOPLASM STAGING; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 33750322234     PISSN: 10766332     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.acra.2006.08.003     Document Type: Article

References (36)

1. Kriege M., Brekelmans C.T.M., Boetes C., et al. Efficacy of MRI and mammography for breast-cancer screening in women with a familial or genetic predisposition. N Engl J Med 351 (2004) 427-437
2. Warner E., Plewes D.B., Hill K.A., et al. Surveillance of BRCA1 and BRCA2 mutation carriers with magnetic resonance imaging, ultrasound, mammography, and clinical breast examination. JAMA 292 (2004) 1317-1325
3. Leach M.O., Brown J., Dixon A.K., et al. Screening with magnetic resonance imaging and mammography of a UK population at high familial risk of breast cancer: a prospective multicenter cohort study. Lancet 365 (2005) 1769-1778
4. Wiener J.I., Schilling K.J., Adami C., et al. Assessment of suspected breast cancer by MRI: a prospective clinical trial using a combined kinetic and morphologic analysis. AJR Am J Roentgenol 184 (2005) 878-886
5. Thibault F., Nos C., Meunier M., et al. MRI for surgical planning in patients with breast cancer who undergo preoperative chemotherapy. AJR Am J Roentgenol 183 (2004) 1159-1168
6. Kitagawa K., Sakuma H., Ishida N., et al. Contrast-enhanced high-resolution MRI of invasive breast cancer: correlation with histopathologic subtypes. AJR Am J Roentgenol 183 (2004) 1805-1809
7. Kuhl C.K., Mielcareck P., Klaschik S., et al. Dynamic breast MR imaging: are signal intensity time course data useful for differential diagnosis of enhancing lesions?. Radiology 211 (1999) 101-110
8. Sardanelli F., Giuseppetti G.M., Panizza P., et al. Sensitivity of MRI versus mammography for detecting foci of multifocal, multicentric breast cancer in fatty and dense breasts using the whole-breast pathologic examination as a gold standard. AJR Am J Roentgenol 183 (2004) 1149-1157
9. Bluemke D.A., Gatsonis C.A., Chen M.H., et al. Magnetic resonance imaging of the breast prior to biopsy. JAMA 292 (2004) 2735-2742
10. Warren R.M.L., Pointon L., Thompson D., et al. Reading protocol for dynamic contrast-enhanced MR images of the breast: sensitivity and specificity analysis. Radiology 236 (2005) 779-788
11. Orel S.G., and Schnall M.D. MR imaging of the breast for the detection, diagnosis, and staging of breast cancer. Radiology 220 (2001) 13-30
12. Kinkel K., and Hylton N.M. Challenges to interpretation of breast MRI. J Magnet Res Imaging 13 (2001) 821-829
13. Morrow M., Strom E.A., Bassett L.W., et al. Standard for the management of ductal carcinoma in situ of the breast (DCIS). Cancer 52 (2002) 256-276
14. Neubauer N., Mengxia L., Kuehne-Heid R., et al. High grade and non-high grade ductal carcinoma in situ on dynamic MR mammography: characteristic findings for signal increase and morphological pattern of enhancement. Br J Radiol 76 (2003) 3-12
15. Szabo B.K., Aspelin P., Kristoffersen, et al. Dynamic MR imaging of the breast. Acta Radiol 44 (2003) 379-386
16. American College of Radiology, BI-RADS, Breast Imaging Reporting and Data System, Breast Imaging Atlas. Breast MRI Imaging (2003), ACR, Reston, VA
17. Wood C. Computer aided detection (CAD) for breast MRI. Technol Cancer Res Treatment 4 (2005) 49-53
18. Chen W., Giger M.L., Lan L., et al. Computerized interpretation of breast MRI: investigation of enhancement variance dynamics. Med Phys 31 (2004) 1076-1082
19. Wang H., Zheng B., Good W.F., et al. Computerized analysis of lesions in 3D MR breast images. In Progess in Biomedical Optics and Imaging (2)27: Proceedings of SPIE 4322 (2001) 1751-1762
20. Gilhuijs K.G.A., Deurloo E.E., Muller S.H., et al. Breast MR imaging in women at increased lifetime risk of breast cancer: clinical system for computerized assessment of breast lesions-initial results. Radiology 225 (2002) 907-916
21. Kelcz F., Furman-Haran E., Grobgeld D., et al. Clinical testing of high-spatial-resolution parametric contrast-enhanced MR imaging of the breast. AJR Am J Roentgenol 179 (2002) 1485-1492
22. Arbach L. Breast MRI: segmentation and classification. Doctoral dissertation (2005), The University of Iowa
23. Gilhuijs K.G.A., Giger M.L., and Bick U. Computerized analysis of breast lesions in three dimensions using dynamic magnetic-resonance imaging. Med Phys 25 (1998) 1647-1654
24. Penn A.I., Bolinger L., Schnall M.D., et al. Discrimination of MR images of breast masses with fractal-interpolation function models. Acad Radiol 6 (1999) 156-163
25. Mussurakis S., Buckley D.L., Coady A.M., et al. Observer variability in the interpretation of contrast enhanced MRI of the breast. Br J Radiol 69 (1996) 1009-1016
26. Kinkel K., Helbich T.H., Esserman L.J., et al. Dynamic high-spatial-resolution MR imaging of suspicious breast lesions: diagnostic criteria and interobserver variability. AJR Am J Roentgenol 175 (2000) 35-43
27. Landis J.R., and Koch G.G. The measurement of observer agreement for categorical data. Biometrics 33 (1977) 159-174
28. Fischer D.R., Wurdinger S., Boettcher J., et al. Further signs in the evaluation of magnetic resonance mammography: a retrospective study. Invest Radiol 40 (2005) 430-435
29. Fischer D.R., Baltzer P., Malich A., et al. Is the 'blooming sign' a promising additional tool to determine malignancy in MR mammography?. Eur Radiol 14 (2004) 394-401
30. Malich A., Fischer D.R., Wurdinger S., et al. Potential MRI interpretation model: differentiation of benign from malignant breast masses. AJR Am J Roentgenol 185 (2005) 964-970
31. Orel S.G., and Schnall M.D. High risk screening working group report. J Magnet Res Imaging 10 (1999) 995-1005
32. Pohlman S., Powell K.A., Obuchowski N.A., et al. Quantitative classification of breast tumors in digitized mammograms. Med Phys 23 (1996) 1337-1345
33. Chakraborty D.P., and Berbaum K.S. Observer studies involving detection and localization: modeling, analysis and validation. Med Phys 31 (2004) 2313-2330
34. Penn AI, Thompson S, Pisano ED, et al. Evaluation of prototype computer-aided diagnosis system to assist radiologists in distinguishing benign from malignant breast lesions on MR: preliminary results of multicenter study. RSNA 2004: SSJ01-04. Available online at http://rsna2004.rsna.org/rsna2004/V2004/conference/event_display.cfm?em_id=4406806. Accessed August 20, 2006.
35. Penn A.I., Thompson S.F., Brem R.F., et al. Impact of CAD on radiologist's discrimination of benign from malignant breast lesions on MR. ISMRM Thirteenth Scientific Meeting and Exhibition (2005) 371
36. Kuhl C.K., and Schild H.H. Dynamic image interpretation of MRI of the breast. J Magn Reson Imaging 12 (2000) 976-974