Evaluation of the anti-inflammatory and membrane-stabilizing effects of Eupatorium odoratum

International Journal of Pharmacology

Volumn 2, Issue 5, 2006, Pages 509-512

  Umukoro, S ^a   Ashorobi, R B ^b  

^a UNIVERSITY OF IBADAN   (Nigeria)

^b UNIVERSITY OF LAGOS   (Nigeria)

Author keywords

Anti imflammatory; Eupatorium odoratum; Membrane stabilizing; Property

Indexed keywords

ACETYLSALICYLIC ACID; CARRAGEENAN; EUPATORIUM ODORATUM EXTRACT; FORMALDEHYDE; HYPOTONIC SOLUTION; PLANT EXTRACT; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; AQUEOUS SOLUTION; ARTICLE; ASTERACEAE; CELL PROTECTION; CHRONIC INFLAMMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DOSE REGIMEN; DRUG SYNTHESIS; EDEMA; ERYTHROCYTE; EUPATORIUM ODORATUM; FEMALE; HEMOLYSIS; MALE; MEMBRANE STABILIZATION; NONHUMAN; PLANT LEAF; RAT;

EID: 33750294417     PISSN: 18117775     EISSN: 18125700     Source Type: Journal    
DOI: 10.3923/ijp.2006.509.512     Document Type: Article

References (21)

1. 2 inhibitors. Biochem. Pharmacol., 51: 737-742.
2. Akah, P.A. and A.I. Nwambie, 1994. Evaluation of Nigerian traditional medicine: Plants used for rheumatic (inflammatory) disorder. J. Ethnopharmacol., 42: 179-182.
3. Biswal, P.R., K.K. Sardar, S.C. Parija, P.R. Mishra and S.N. Mishra, 1997. Wounding healing effect Eupatorium odoratum linn and himax in rabbits. Ind. J. Indigenous Med., 19: 71-74.
4. Cotran, R.S., V. Kumar and T. Collins, 1999. Acute and Chronic Inflammation. In: Robbbins Pathologic Basis of Diseases, 6th Edn., Saunders Company New York., pp: 50-88.
5. Cragg, G.M. and D.J. Newman, 2001. Natural products drug discovery in the next millennium. Pharm. Biol., 39: 8-17.
6. Dewhirst, T.E., 1980. Structure activity relationships for inhibition of prostaglandin cyclo-oxygenase by phenolic compounds. Prostaglandins, 20: 209-222.
7. Dirosa, M., J.P. Giround and D.A. Willoughby, 1971. Studies of the mediators of acute inflammatory response induced in rats in different sites by carrageenan and turpentine. J. Pathol., 104: 15-29.
8. Ferrali, M., C. Signorni, L. Ciccoli and M. Comporti, 1992. Iron release and membrane damage in erythrocytes exposed to oxidizing agents, phenylhydrazine, divicine and isouramil. Biochem. J., 285: 295-301.
9. Ferrandiz M. and M.J. Alcaraz, 1991. Anti-inflammatory activity and inhibition of arachidonic acid metabolites by flavonoids. Agents and Actions, 32: 283-288.
10. Jain, P. and N.K. Khanna, 1981, Evaluation of anti-inflammatory and analgesic properties of L-glutamine. Agent and Actions, 11: 242-249.
11. 50 and its errors by means of logarithmic-probit graph paper. Proc. Soc. Exp. Biol. Med., 57:261-264.
12. Nunez-Guillen, M.E., J.A. Silva-Emimi, C. Souccar and A.I. Lmdala, 1997. Analgesic and anti-inflammatory activities of the aqueous extract of Plantago major L. Intl. J. Pharmacognosy, 35: 99-104.
13. Oriowo, M.A., 1982. Anti-inflammatory activity of piperronly-4-acrylic isobutylamide, an extractive of Zanthoxylum zanthoxyloid. Planta Medica, 44: 54-58.
14. Perenz, R.M., S. Perenz, M.A. Zavala and M. Salazar, 1995. Anti-inflammatory activity of the bark of Hippocratea excelsa. J. Ethnopharmacol., 47: 85-90.
15. Phan, T.T., M.A. Hughes, G.W. Cherry, T.T. Le and H.M. Pham, 1996. An aqueous extract of the leaves Chromolaena odoratum (formerly Eupatorium odoratum) (eupolin) inhibits hydrated collagen lattice contraction by normal human dermal fibroblasts. J. Altern Complement Med., 335-343.
16. Richter, L.A., J. Salazar and E. Rodriguez, 2003. A phytochemical analysis to suggest new applications of anti-inflammatory plants from the Dominican Republic. Emanations, 4: 24-30.
17. Shinde, U.A., A.S. Phadke, A.M. Nair, A.A. Mungantiwar, V.J. Dikshit and V.O. Saraf, 1999. Membrane stabilizing activity-a possible mechanism of action for the anti-inflammatory activity of Cedrus deodara wood oil. Fitoterapia, 70: 251-257.
18. Tjolsen, A., O. Berge, S. Hunskaar, J.H. Rosland and K. Hole, 1992. The formalin test: An evaluation of the method. Pain, 51: 5-14.
19. Triratana, T., R. Suwannuraks and W. Naengchommonong, 1991. Effect of Eupatorium odoratum on blood coagulation. J. Med. Assoc. Thai., 74: 283-287.
20. Vandebroek, I., J. Calewaert, S. Dejonckheere, S. Sanca, L. Semo, P.V. Damme, L.V. Puyvelde and N.D. Kimpe, 2004. Use of medicinal plants and pharmaceuticals by indigenous communities in the Bolivain Andes and Amazon. Bull. World Health Organ., 82: 243-250.
21. Winter, C., E. Risley and O. Nuss, 1962. Carrageenin-induced inflammation in the hind limb of the rat. Fed. Proc., 46: 118-126.