4-Alkoxybenzamidines as new potent phospholipase A2 inhibitors

Biochemical Pharmacology

Volumn 51, Issue 6, 1996, Pages 737-742

  Aitdafoun, Mina ^a   Mounier, Carine ^b   Heymans, Françoise ^a   Binisti, Carine ^a   Cassian, Bon ^b   Godfroid, Jean Jacques ^a  

^a Laboratoire de Pharmacochimie   (France)

^b INSTITUT PASTEUR   (France)

Author keywords

benzamidine; carrageenan induced oedema; extracellular PLA2; PLA2 inhibitor

Indexed keywords

4 HEXADECYLOXYBENZAMIDINE; 4 TETRADECYLOXYBENZAMIDINE; BENZAMIDINE DERIVATIVE; CARRAGEENAN; INDOMETACIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; PHOSPHOLIPASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CATTLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; INFLAMMATION; LIPOPHILICITY; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PANCREAS; PAW EDEMA; PRIORITY JOURNAL; RABBIT; RAT; STRUCTURE ACTIVITY RELATION; THROMBOCYTE;

EID: 0029995075     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(95)02172-8     Document Type: Article

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