Transfection of the DNA for the Receptor KDR/flk-1 Attenuates Neointimal Proliferation and Luminal Narrowing in a Coronary Stent Angioplasty Model

Journal of Surgical Research

Volumn 136, Issue 1, 2006, Pages 120-124

  Buchwald, Arnd B ^a   Kunze, Christopher ^b   Waltenberger, Johannes ^c   Unterberg Buchwald, Christina ^b  

^a Stadtisches Krankenhaus Kiel   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

coronary angioplasty; DNA transfer; restenosis; vascular endothelial growth factor receptor KDR flk 1

Indexed keywords

DNA; VASCULOTROPIN RECEPTOR 2;

ANGIOPLASTY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CORONARY STENT; GENETIC CODE; GENETIC TRANSFECTION; ILIAC ARTERY; IN SITU HYBRIDIZATION; INTIMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; RECEPTOR BINDING; RESTENOSIS;

ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; ANIMALS; CELL DIVISION; CORONARY RESTENOSIS; DNA; GENE THERAPY; IN SITU HYBRIDIZATION; LAC OPERON; RNA, MESSENGER; STENTS; SWINE; SWINE, MINIATURE; TRANSFECTION; TUNICA INTIMA; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 33750290801     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2006.06.011     Document Type: Article

References (30)

1. Fishman D.L., Leon M.B., Baim D.S., et al. A randomized comparison of coronary stent placement and balloon angioplasty in the treatment of coronary artery disease. N Engl J Med 331 (1994) 496
2. Serruys P.W., De Jaegere P., Kiemeneji F., et al. A comparison of balloon-expandable-stent implantation with balloon angioplasty in patients with coronary artery disease. N Engl J Med 331 (1994) 489
3. Williams D.O., Holubkov R., Yeh W., et al. Percutaneous coronary intervention in the current era compared with 1985-1986. Circulation 102 (2000) 2945
4. Savage M.P., Fischman D.L., Rake R., et al. Efficacy of coronary stenting versus balloon angioplasty in small coronary arteries. Stent restenosis study (STRESS) investigators. J Am Coll Cardiol 31 (1998) 307
5. Karas S.P., Gravanis M.B., Santoian E.C., Robinson K.A., Anderberg K.A., and King III S.B. Coronary intimal proliferation after balloon injury and stenting in swine: An animal model of restenosis. J Am Coll Cardiol 20 (1992) 467
6. Hoffmann R., Mintz G.S., Dussaillant G.R., et al. Patterns and mechanisms of in-stents restenosis: A serial ultrasound study. Circulation 94 (1996) 1247
7. Kearney M., Pieczek A., Haley L., et al. Histopathology of in-stent restenosis in patients with peripheral artery disease. Circulation 95 (1997) 1998
8. Terman B.I., Dougher-vermozen M., Carrion M.E., et al. Identification of the KDR tyrosine kinase as a receptor for vascular endothelial growth factor. Biochem Biophys Res Commun 187 (1992) 1579
9. Clowes A.W., Collazzo R.E., and Karnovsky M.J. A morphologic and permeability study of luminal smooth muscle cells after arterial injury in the rat. Lab Invest 39 (1978) 141
10. Bjorkerud S., and Bondjers G. Arterial repair and atherosclerosis after mechanical injury, part 5: Tissue response after induction of a large superficial transverse injury. Atherosclerosis 18 (1973) 235
11. Fishman J.R., Ryan G.B., and Karnovsky M.J. Endothelial regeneration in the rat carotid artery and the significance of endothelial denudation in the pathogenesis of myointimal thickening. Lab Invest 32 (1975) 339
12. Haudenshild C.C., and Schwartz S. Endothelial regeneration. II: Restitution of endothelial continuity. Lab Invest 41 (1979) 407
13. Ross R. Atherosclerosis: A defense mechanism gone awry. Am J Pathol 143 (1993) 985
14. Chen Y.X., Nakashima Y., Tanaka K., Shiraishi S., Nakagawa K., and Sueishi K. Immunohistochemical expression of vascular endothelial growth factor/vascular permeability factor in atherosclerotic intimas of human coronary arteries. Arterioscler Thromb Vasc Biol 19 (1999) 131
15. Hausner E.A., Orsini J.A., Foster L.L., et al. Vascular endothelial growth factor in porcine coronary arteries following balloon angioplasty. J Invest Surg 12 (1999) 15
16. Ferrara N., and Henzel W.J. Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem Biophys Res Commun 161 (1989) 851
17. Keck P.J., Hauser S.D., Krivi G., Sanzo K., Warren T., Feder J., and Conolly D.T. Vascular permeability factor, an endothelial cell mitogen related to PDGF. Science 246 (1989) 1309
18. Plouet J., Schilling J., and Gospodarowicz D. Isolation and characterization of a newly identified endothelial cell mitogen produced by ACT-20 cells. EMBO J 8 (1989) 3801
19. Asahara T., Bauters C., Pastore C., et al. Local delivery of vascular endothelial growth factor accelerates reendothelialization and attenuates intimal hyperplasia in balloon-injured rat carotid artery. Circulation 91 (1995) 2793
20. Asahara T., Chen D., Tsunumi Y., et al. Accelerated restitution of endothelial integrity and endotelium-dependent function after phVEGF 165 gene transfer. Circulation 94 (1996) 3291
21. Buchwald A.B., Unterberg C., Nebendahl K., Gröne H.J., and Wiegand V. Low-molecular weight heparin reduces neointimal proliferation after coronary stent implantation in hypercholesterolemic minipigs. Circulation 86 (1992) 531
22. Unterberg C., Sandrock D., Nebendahl K., and Buchwald A.B. Reduced acute thrombus formation results in decreased neointimal proliferation after coronary angioplasty. J Am Coll Cardiol 26 (1995) 1747
23. Schwartz R.S., Huber K.C., Murphy J.G., et al. Restenosis and the proportional neointimal response to coronary artery injury: Results in a porcine model. J Am Coll Cardiol 19 (1992) 267
24. Waltenberger J., Claesson-Welsh L., Siegbahn A., Shibuya M., and Heldin C.H. Different signal transduction properties of KDR and Flt 1, two receptors for vascular endothelial growth factor. Biol Chem 269 (1994) 26988
25. Buchwald A.B., Meyer T., Stevens J., et al. Vascular endothelial growth factor expression in reendothelialisation and neovascularisation in a coronary angioplasty model. Eur Heart J 18 (1997) 154
26. Sousa J.E., Costa M.A., Abizaid A., et al. Four-year angiographic and intravascular ultrasound follow-up of patients treated with sirolimus-eluting stents. Circulation 111 (2005) 2326
27. Morice M.-C., Serruys P.W., Souse J.E., et al. randomized comparison of a sirolimus eluting stent with a standard stent for coronary revascularization. N Engl J Med 346 (2002) 1773
28. Moses J.W., Leon M.B., Popma J.J., et al. Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery. N Engl J Med 349 (2003) 1315
29. Schofer J., Schlüter M., Gershlick A.H., et al. Sirolius-eluting stents for treatment of patients with long atherosclerotic lesions in small coronary arteries: Double-blind, randomised controlled trial (E-SIRIUS). Lancet 362 (2003) 1093
30. Grube E., Silber S., Hauptmann K.E., et al. TAXUS I: Six and twelve month results from a randomized, double-blind trial on a slow-release paclitaxel-eluting stent for de novo coronary lesions. Circulation 107 (2003) 38