An optimized microchip electrophoresis system for mutation detection by tandem SSCP and heteroduplex analysis for p53 gene exons 5-9

Electrophoresis

Volumn 27, Issue 19, 2006, Pages 3823-3835

  Hestekin, Christa N ^a   Jakupciak, John P ^b   Chiesl, Thomas N ^a   Kan, Cheuk Wai ^a   O'Connell, Catherine D ^c   Barron, Annelise E ^a  

^a Northwestern University   (United States)

^b NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

^c TETRACORE INC   (United States)

Author keywords

Heteroduplex analysis; Linear polyacrylamide; Microchip electrophoresis; Mutation detection; P53

Indexed keywords

CLINICAL RESEARCH; DNA; ELECTRIC FIELDS; GENES; MATRIX ALGEBRA; MICROPROCESSOR CHIPS; PLASTIC COATINGS; RESEARCH LABORATORIES;

HETERODUPLEX ANALYSIS; LINEAR POLYACRYLAMIDES; MICROCHIP ELECTROPHORESIS; MUTATION DETECTION; P53 GENE; POLYMER MATRICES; POLYMORPHISM ANALYSIS; SINGLE STRAND CONFORMATIONAL POLYMORPHISM; SLAB-GEL ELECTROPHORESIS; WALL COATINGS;

ELECTROPHORESIS;

DNA; POLYACRYLAMIDE; POLYMER; PROTEIN P53;

ANALYTIC METHOD; ANALYTICAL PARAMETERS; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA DETERMINATION; ELECTRIC FIELD; EXON; HETERODUPLEX ANALYSIS; HUMAN; LOW TEMPERATURE; MATERIAL COATING; MICROCHIP ELECTROPHORESIS; MOLECULAR DYNAMICS; MOLECULAR WEIGHT; MUTATIONAL ANALYSIS; PROCESS OPTIMIZATION; RELIABILITY; SENSITIVITY ANALYSIS; SEPARATION TECHNIQUE; SINGLE STRAND CONFORMATION POLYMORPHISM; STRENGTH; TEMPERATURE MEASUREMENT;

EID: 33750236400     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.200600358     Document Type: Article

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