Lithium induces phosphoglucomutase activity in various tissues of rats and in bipolar patients

International Journal of Neuropsychopharmacology

Volumn 9, Issue 5, 2006, Pages 613-619

  Csutora, Péter ^a   Karsai, Árpád ^a   Nagy, Tamás ^a   Vas, Bálint ^a   Kovács, Gábor L ^a   Rideg, Orsolya ^a   Bogner, Péter ^a   Miseta, Attila ^a  

^a UNIVERSITY OF PÉCS   (Hungary)

Author keywords

Bipolar disorder; Glucose phosphate; Lithium; Magnesium; Phosphoglucomutase

Indexed keywords

CARBAMAZEPINE; GLUCOSE PHOSPHATE; LITHIUM; PHOSPHOGLUCOMUTASE; VALPROIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIPOLAR DISORDER; CELL ISOLATION; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN CELL; LEUKOCYTE; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; RAT STRAIN;

ANIMALS; ANTIMANIC AGENTS; BIPOLAR DISORDER; BRAIN; CALCIUM; GLUCOSE-6-PHOSPHATE; GLUCOSEPHOSPHATES; HUMANS; LEUKOCYTES; LITHIUM CHLORIDE; LIVER; MAGNESIUM; MALE; MUSCLE, SKELETAL; MYOCARDIUM; PHOSPHOGLUCOMUTASE; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 33750211708     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1017/S146114570500622X     Document Type: Article

References (25)

1. 2+ in human neuroblastoma SH-SY5Y cells. Bipolar Disorders 5, 6-13.
2. 2+ homeostasis in Saccharomyces cerevisiae. Journal of Biological Chemistry 277, 45751-45758.
3. 2+-ATPase Pmc1p. Journal of Biological Chemistry 279, 38495-38502.
4. 31P NMR study. Biophysical Journal 76, 2934-2942.
5. Bergmayer HU (1984). Methods of enzymatic analysis. In: Methods of Enzymatic Analysis (3rd edn). Weinheim, Germany: Verlag Chemie.
6. Berridge MJ, Irvine RF (1989). Inositol phosphates and cell signalling. Nature 341, 197-205.
7. Csutora P, Strassz A, Boldizsár F, Németh P, Sipos K, Aiello DP, Bedwell DM, Miseta A (2005). Inhibition of phosphoglucomutase activity by lithium alters cellular calcium homeostasis and signaling in Saccharomyces cerevisiae. American Journal of Physiology - Cell Physiology. Published online 9 February 2005. doi:10.1152/ajpcell.00464.2004
8. Dinan TG (2002). Lithium in bipolar mood disorder. British Medical Journal 324, 989-990.
9. Fu L, Bounelis P, Dey N, Browne BL, Marchase RB, Bedwell DM (1995). The posttranslational modification of phosphoglucomutase is regulated by galactose induction and glucose repression in Saccharomyces cerevisiae. Journal of Bacteriology 177, 3087-3094.
10. Fu L, Miseta A, Hunton D, Marchase RB, Bedwell DM (2000). Loss of the major isoform of phosphoglucomutase results in altered calcium homeostasis in Saccharomyces cerevisiae. Journal of Biological Chemistry 275, 5431-5440.
11. Gould TD, Manji HK (2002). The Wnt signaling pathway in bipolar disorder. Neuroscientist 8, 497-511.
12. Gould TD, Quiroz JA, Singh J, Zarate CA, Manji HK (2004). Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizers. Molecular Psychiatry 9, 734-755.
13. Grubbs RD (2002). Intracellular magnesium and magnesium buffering. Biometals 15, 251-259.
14. Lenox RH, Wang L (2003). Molecular basis of lithium action: integration of lithium-responsive signaling and gene expression networks. Molecular Psychiatry 8, 135-144.
15. Manji HK, Moore GJ, Chen G (2001). Bipolar disorder: leads from the molecular and cellular mechanisms of action of mood stabilizers. British Journal of Psychiatry 178, S107-119.
16. Mansour HA, Alda M, Nimgaonkar VL (2002). Pharmacogenetics of bipolar disorder. Current Psychiatry Reports 4, 117-123.
17. Masuda CA, Xavier MA, Mattos KA, Galina A, Montero-Lomeli M (2001). Phosphoglucomutase is an in vivo lithium target in yeast. Journal of Biological Chemistry 276, 37794-37801.
18. Miseta A, Bogner P, Berenyi E, Kellermayer M, Galambos C, Wheatley DN, Cameron IL (1993). Relationship between cellular ATP, potassium, sodium and magnesium concentrations in mammalian and avian erythrocytes. Biochimica et Biophysica Acta 1175, 133-139.
19. Muller-Oerlinghausen B, Berghofer A, Bauer M (2002). Bipolar disorder. Lancet 359, 241-247.
20. Nordenberg J, Kaplansky M, Beery E, Klein S, Beitner R (1982). Effects of lithium on the activities of phosphofructokinase and phosphoglucomutase and on glucose-1,6-diphosphate levels in rat muscles, brain and liver. Biochemical Pharmacology 31, 1025-1031.
21. Ray Jr. WJ, Szymanki ES, Ng L (1978). The binding of lithium and of anionic metabolites to phosphoglucomutase. Biochimica et Biophysica Acta 522, 434-442.
22. Rivera AA, Elton TS, Dey NB, Bounelis P, Marchase RB (1993). Isolation and expression of a rat liver cDNA encoding phosphoglucomutase. Gene 133, 261-266.
23. Saris NE, Mervaala E, Karppanen H, Khawaja JA, Lewenstam A (2000). Magnesium. An update on physiological, clinical and analytical aspects. Clinica Chimica Acta 294, 1-26.
24. Sassi RB, Soares JC (2001). Emerging therapeutic targets in bipolar mood disorder. Expert Opinion on Therapeutic Targets 5, 587-599.
25. Tokés-Fozesi M, Bedwell DM, Repa I, Sipos K, Sümegi B, Rab A, Miseta A (2002). Hexose phosphorylation and the putative calcium channel component Mid1p are required for the hexose-induced transient elevation of cytosolic calcium response in Saccharomyces cerevisiae. Molecular Microbiology 44, 1299-1308.