Cytotoxic activity of the Inula japonica extracts against several human cancer cell lines in vitro

Korean Journal of Pharmacognosy

Volumn 37, Issue 3, 2006, Pages 130-135

  Cha, Mi Ran ^a   Kim, Ju Young ^a   Hwang, Ji Hwan ^a   Park, Hae Ryong ^a  

^a Kyungnam University   (South Korea)

Author keywords

Cytotoxic activity; Human cancer cells; Inula japonica; MTT assay

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ACETIC ACID ETHYL ESTER; ACETONE; ALCOHOL; ANTIINFECTIVE AGENT; ETHER; HERBACEOUS AGENT; HEXANE; INULA JAPONICA EXTRACT; METHANOL; PLANT EXTRACT; UNCLASSIFIED DRUG; WATER;

ARTICLE; BREAST ADENOCARCINOMA; BREAST CANCER; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CELL STRAIN HT29; CELL STRAIN MCF 7; COLON CANCER; COLON CARCINOMA; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; FRACTIONATION; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INULA; UTERINE CERVIX CARCINOMA;

EID: 33750211049     PISSN: 02533073     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Seol, K. L., Choi, S. Y. and Lee, J. I. (2002) A study on the use, understanding and satisfaction with alternative therapy for hospitalized cancer patients. J. Korean Public Health Assoc. 28: 198-211.
2. Joo, H. Z., Lee, H. S. and Lee, T. S. (1992) A clinical study of 5-year survival rate of stomach cancer according to post-operative anticancer chemotherapy. J. Korean Cancer Assoc. 24: 140-148.
3. Park, K. J., Kim, E. H., Eun, Y. A., Kang, B. J. and Sung, H. J. (1997) Cytotoxic effect of Korean traditional prescriptions on the human gastric cancer cell lines. Kor. J. Phamacogn. 28: 233-238.
4. 2 in tumor tissue. J. Med. Chem. 48: 7305-7314.
5. Xu, F., Zhang, S. H., Shao, R. G. and Zhen, Y. S. (2005) Anticancer activity of sodium caffeate and its mechanism. Acta Phamacol Sin. 26: 1248-1252.
6. Ryu, B. H., Park, B. G. and Song, S. K. (2002) Antitumor effects of the hexane extract of Stachys Sieboldii MIQ. Korean J. Biotechnol. Bioeng. 17: 520-524.
7. Fojo, A. T., Ueda, K., Slamon, D. J., Poplack, D. G., Gottesman, M. M. and Pastan, I. (1987) Expression of a multidrug-resistance gene in human tumors and tissues. Proc. Natl. Acad. Sci. 84: 265-269.
8. Chung, H. W., Choi, J. Y. and Lee, W. Y. (1988) Cell size heterogeneity due to anticancer drug which might indicate resistance. J. Korean Public Health Assoc. 14: 35-46.
9. Yoon, T. J., Lee, C. K., Park, T. K. and Lee, K. H. (2005) Immunostimulant and anti-tumor activity of crude extracts of Galium aparine L. Kor. J. Pharmacogn. 36: 332-337.
10. Smtyh, M. J., Thia, K. Y. T., Cretney, E., Kelly, J. M., Snook, M. B., Forbes, C. A. and Scalzo, A. A. (1999) Perforin is a major contributor to NK cell control of tumor metastasis. J. Immunol. 162: 6658-6662.
11. Sunami, E., Tsuno, N., Osada, T., Saito, S., Kitayama, J., Tomozawa, S., Tsuruo, T., Shibata, Y., Muto, T. and Nagawa, H. (2000) MMP-1 is a prognostic marker for hematogenous metastasis of colorectal cancer. The Oncologist 5: 108-114.
12. Hanna, N. (1980) Expression of metastatic potential of tumor cells in young nude mice is correlated with low levels of natural killer cell mediated cytotoxicity. Int. J. Cancer. 26: 675-680.
13. Park, H. R., Tomida, A., Sato, S., Tsukumo, Y., Yun, J., Yamori, T., Hayakawa, Y., Tsuruo, T. and Shin-ya, K. (2004) Effect on tumor cells of blocking survival response to glucose deprivation. J. Natl. Cancer Inst. 96: 1300-1310.
14. Kobayashi, T., Song, Q. H., Hong, T., Kitamura, H. and Cyong, J. C. (2002) Preventative active effects of the flowers of Inula britannica on autoimmune diabetes in C57BL/KsJ mice induced by multiple low doses of streptozotocin. Phytother. Res. 16: 377-382.
15. Yang, C., Wang, C. M. and Jia, Z. J. (2003) Sesquiterpenes and other constituents from the aerial parts of Inula japonica. Planta. Med. 69: 662-666.
16. Sunwoo, S., Kim, H. S. and Byun, K. S. (1991) Studies on the volatile components of Inulae flos. J. Korean Agric. Chem. Soc. 34: 312-317.
17. Shan, J. J., Yang, M. and Ren, J. W. (2006) Anti-diabetic and hypolipidemic effects of aqueous-extract from the flower of Inula japonica in alloxan-induced diabetic mice. Biol. Pharm. Bull. 29: 455-459.
18. Zheng, M. S. (1989) An exprimental study of the anti-HSV-II action of 500 herbal drugs. J. Tradit. Chin. Med. 9: 113-116.