updAIDS: Preventing and diagnosing HIV infection in infants and children

South African Family Practice

Volumn 48, Issue 6, 2006, Pages 34-41

  Rabie, H ^b   Marais, B J ^b   Cotton, M F ^b   Reuter, Helmut ^a  

^a STELLENBOSCH UNIVERSITY   (South Africa)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

COTRIMOXAZOLE; NEVIRAPINE; ZIDOVUDINE;

CESAREAN SECTION; CLINICAL FEATURE; DISEASE SEVERITY; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFANT FEEDING; INTRAPARTUM CARE; PRACTICE GUIDELINE; PREGNANCY; PUERPERIUM; REVIEW; RISK FACTOR; VAGINAL DELIVERY; VERTICAL TRANSMISSION; VIRUS LOAD; VIRUS TRANSMISSION;

EID: 33750159187     PISSN: 20786190     EISSN: 20786204     Source Type: Journal    
DOI: 10.1080/20786204.2006.10873407     Document Type: Review

References (34)

1. http://www.who.int/hiv/paediatric/en/index.html
2. Chermann JC. Sexual and mother-to-child transmission of the human immunodeficiency virus type 1: a review. Am J Reprod Immunol 1998;40:183-6
3. Matheson PB, Weedon J, Cappelli M, Abrams EJ, Shaffer N, Bamji M, Krasinski K, Lambert G, Kaul A, Grimm K, et al. Comparison of methods of estimating the mother-to-child transmission rate of human immunodeficiency virus type 1 (HIV-1). New York City Perinatal HIV Transmission Collaborative Study Group. Am J Epidemiol 1995;142: 714-8
4. Bobat R, Coovadia H, Coutsoudis A, Moodley D. Determinants of mother-to-child transmission of human immunodeficiency virus type 1 infection in a cohort from Durban, South Africa. PIDJ 1996; 15: 604-10
5. Bertolli J, St Louis ME, Simonds RJ, Nieburg P, Kamenga M, Brown C, Tarande M, Quinn T, Ou CY. Estimating the timing of mother-to-child transmission of human immunodeficiency virus in a breast-feeding population in Kinshasa, Zaire. J Infect Dis 1996;174: 722-6
6. Schaaf HS. Human immunodeficiency virus infection and child sexual abuse. S Afr Med J 2004;94: 782-5
7. Grobbelaar BG. The impact of AIDS on blood transfusion services in South Africa. Med Law 1992;11: 495-500
8. Yerly S, Quadri R, Negro F, Barbe KP, Cheseaux JJ, Burgisser P, Siegrist CA, Perrin L. Nosocomial outbreak of multiple bloodborne viral infections. J Infect Dis 2001;184: 369-72
9. Orth H, Engelbrecht S, Cotton MF, Robson BA, Smith TL, Schaaf HS, Leibrandt B, Dobbels E, van Rensburg EJ. HIV transmission between two siblings in Africa. AIDS 2000;14: 896-7
10. Hiemstra R, Rabie H, Schaaf HS, Eley B, Cameron N, Mehtar S, Janse van Rensburg A, Cotton MF. Unexplained HIV-1 infection in children - documenting cases and assessing for possible risk factors. S Afr Med J 2004;94: 188-93
11. Cooper ER, Charurat M, Mofenson L, Hanson IC, Pitt J, Diaz C, Hayani K, Handelsman E, Smeriglio V, Hoff R, Blattner W, Combination antiretroviral strategies for the treatment of pregnant HIV-1-infected women and prevention of perinatal HIV-1 transmission. J Acquir Immune Defic Syndr 2002;29: 484-94
12. Guay LA, Musoke P, Fleming T, Bagenda D, Allen M, Nakabiito C, Sherman J, Bakaki P, Ducar C, Deseyve M, Emel L, Mirochnick M, Fowler MG, Mofenson L, Miotti P, Dransfield K, Bray D, Mmiro F, Jackson J B. Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: HIVNET 012 randomised trial. Lancet 1999;354: 795-802
13. Marseille E, Kahn JG, Mmiro F, Guay L, Musoke P, Fowler MG, Jackson JB. Cost effectiveness of single-dose nevirapine regimen for mothers and babies to decrease vertical HIV-1 transmission in sub-Saharan Africa. Lancet 1999;354: 803-9
14. Eshleman SH, Hoover DR, Chen S, Hudelson SE, Guay LA, Mwatha A, Fiscus SA, Mmiro F, Musoke P, Jackson JB, Kumwenda N, Taha T. Resistance after single-dose nevirapine prophylaxis emerges in a high proportion of Malawian newborns. AIDS 2005;19:2167-9
15. Eshleman SH, Hoover DR, Chen S, Hudelson SE, Guay LA, Mwatha A, Fiscus SA, Mmiro F, Musoke P, Jackson JB, Kumwenda N, Taha T. Nevirapine (NVP) resistance in women with HIV-1 subtype C, compared with subtypes A and D, after the administration of single-dose NVP. J Infect Dis 2005;192: 30-6
16. Lallemant M, Jourdain G, Le Coeur S, Mary JY, Ngo-Giang-Huong N, Koetsawang S, Kanshana S, McIntosh K, Thaineua V. Single-dose perinatal nevirapine plus standard zidovudine to prevent mother-to-child transmission of HIV-1 in Thailand. N Engl J Med 2004;351: 217-28
17. McIntyre J. Strategies to prevent mother-to-child transmission of HIV. Curr Opin Infect Dis 2006;19: 33-8
18. Dunn DT, Newell M L, Ades AE, Peckham CS. Risk of human immunodeficiency virus type 1 transmission through breast-feeding. Lancet 1992; 340:585-8
19. Coutsoudis A, Pillay K, Kuhn L, Spooner E, Tsai WY, Coovadia HM. Method of feeding and transmission of HIV-1 from mothers to children by 15 months of age: prospective cohort study from Durban, South Africa. AIDS 2001; 15: 379-87
20. Hartmann SU, Berlin CM, Howett MK. Alternative modified infant-feeding practices to prevent postnatal transmission of human immunodeficiency virus type 1 through breast milk: past, present, and future. J Hum Lact 2006;22: 75-88
21. Shapiro R L, Ndung'u T, Lockman S, Smeaton L M, Thior I, Wester C, Stevens L, Sebetso G, Gaseitsiwe S, Peter T, Essex M. Highly active antiretroviral therapy started during pregnancy or postpartum suppresses HIV-1 RNA, but not DNA, in breast milk. J Infect Dis 2005;192: 713-9
22. Colebunders R, Hodossy B, Burger D, Daems T, Roelens K, Coppens M, Van Bulck B, Jacquemyn Y, Van Wijngaerden E, Fransen K. The effect of highly active antiretroviral treatment on viral load and antiretroviral drug levels in breast milk. AIDS 2005;19: 1912-5
23. Doherty T, Chopra M, Nkonki L, Jackson D, Greiner T. Effect of the HIV epidemic on infant feeding in South Africa: "When they see me coming with the tins they laugh at me". Bull World Health Organ 2006;84: 90-6
24. Chantry CJ, Cooper ER, Pelton SI, Zorilla C, Hillyer GV, Diaz C. Seroreversion in human immunodeficiency virus-exposed but uninfected infants. Pediatr Infect Dis J 1995;14: 382-7
25. Dickover RE, Dillon M, Leung KM, Krogstad P, Plaeger S, Kwok S, Christopherson C, Deveikis A, Keller M, Stiehm ER, Bryson YJ. Early prognostic indicators in primary perinatal human immunodeficiency virus type 1 infection: importance of viral RNA and the timing of transmission on long-term outcome. J Infect Dis 1998;178: 375-87
26. Jones SA, Sherman GG, Coovadia AH. Can clinical algorithms deliver an accurate diagnosis of HIV infection in infancy? Bull World Health Organ 2005;83: 559-60
27. Sherman GG, Cooper PA, Coovadia AH, Puren AJ, Jones SA, Mokhachane M, Bolton KD. Polymerase chain reaction for diagnosis of human immunodeficiency virus infection in infancy in low resource settings. Pediatr Infect Dis J 2005;24: 993-7
28. Nesheim S, Palumbo P, Sullivan K, Lee F, Vink P, Abrams E, Bulterys M. Quantitative RNA testing for diagnosis of HIV-infected infants. J Acquir Immune Defic Syndr 2003;32: 192-5
29. Zijenah LS, Tobaiwa O, Rusakaniko S, Nathoo KJ, Nhembe M, Matibe P, Katzenstein DA. Signal-boosted qualitative ultrasensitive p24 antigen assay for diagnosis of subtype C HIV-1 infection in infants under the age of 2 years. J Acquir Immune Defic Syndr 2005;39: 391-4
30. Blanche S, Newell ML, Mayaux MJ, Dunn DT, Teglas JP, Rouzioux C, Peckham CS. Morbidity and mortality in European children vertically infected by HIV-1. The French Paediatric HIV Infection Study Group and European Collaborative Study. J Acquir Immune Defic Syndr Hum Retrovirol 1997;14: 442-50
31. Spira R, Lepage P, Msellati P, Van De Perre P, Leroy V, Simonon A, Karita E, Dabis F. Natural history of human immunodeficiency virus type 1 infection in children: a five-year prospective study in Rwanda. Mother-to-Child HIV-1 Transmission Study Group. Paediatrics 1999;104: e56
32. Newell ML, Coovadia H, Cortina-Borja M, Rollins N, Gaillard P, Dabis, F. Mortality of infected and uninfected infants born to HIV-infected mothers in Africa: a pooled analysis. Lancet 2004;364: 1236-43
33. Van Kooten Niekerk NK, Knies MM, Howard J, Rabie H, Zeier M, van Rensburg A, Frans N, Schaaf HS, Fatti G, Little F, Cotton MF. The first 5 years of the family clinic for HIV at Tygerberg Hospital: family demographics, survival of children and early impact of antiretroviral therapy. J Trop Pediatr 2006;52: 3-11
34. Connor, EM et al. Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. Paediatric AIDS Clinical Trials Group Protocol 076 Study Group N Engl J Med 1994; 331: 1173-80