Genetic predisposition - Is lupus nephritis a question of copy numbers?

Nephrology Dialysis Transplantation

Volumn 21, Issue 9, 2006, Pages 2378-2379

  Schwarting, Andreas ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Genetics; Lupus nephritis

Indexed keywords

AUTOANTIBODY; FC RECEPTOR;

ANTIGEN ANTIBODY COMPLEX; ARTICLE; AUTOIMMUNE DISEASE; DISEASE COURSE; ENVIRONMENTAL FACTOR; ETHNOLOGY; GENETIC PREDISPOSITION; GENOTYPE; HEREDITY; HUMAN; LUPUS ERYTHEMATOSUS NEPHRITIS; MAJOR HISTOCOMPATIBILITY COMPLEX; PATHOGENESIS; PRIORITY JOURNAL; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMIC LUPUS ERYTHEMATOSUS; EDITORIAL; GENE DOSAGE; GENETICS;

GENE DOSAGE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LUPUS NEPHRITIS; RECEPTORS, FC; RISK FACTORS;

EID: 33750143349     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfl333     Document Type: Article

References (19)

1. Block SR, Winfield JB, Lokshin MD, D'Angelo WA, Christian CL. Studies of twins with systemic lupus erythematosus. A review of the literature and presentation of 12 additional sets. Am J Med 1975; 59: 533-552
2. Deapen D, Escalante A, Weinrib L et al. A revised estimate of twin concordance in system lupus erythematosus. Arthritis Rheum 1992; 35: 311-318
3. Arnett FC, Reveille JD, Wilson RW, Provost TT, Bias WB. Systemic lupus erythematosus: Current state of genetic hypothesis. Semin Arthritis Rheum 1984; 14: 24-35
4. Croker JA, Kimberly RP. SLE: Challenges and candidates in human disease. Trends Immunol 2006; 26: 580-586
5. Tsao BP. Update on human systemic lupus erythematosus genetics. Curr Opin Rheumatol 2004; 16: 513
6. Pickering MC, Botto M, Taylor PR, Lachmann PJ, Walport MJ. Systemic lupus erythematosus, complement deficiency and apoptosis. Adv Immunol 2000; 76: 227-324
7. Takai T. Fc Receptors and their role in regulation and autoimmunity. J Clin Immunol 2005; 25: 1-18
8. Karassa FB, Bijl M, Davies KA et al. Role of the Fcgamma receptor IIA polymorphism in the antiphospholipid syndrome: An international meta-analysis. Arthritis Rheum 2003; 48: 1930-1938
9. Salmon JE, Millard S, Schachter LA et al. Fc gamma RIIA alleles are heritable risk for SLE nephritis in African Americans. J Clin Invest 1996; 97: 1348-1354
10. Edberg JC, Langfeld CD, Wu J et al. Genetic linkage and association of Fcgr Receptor IIIA (CD16A) on chromosome 1q23 with human systemic lupus erythematosus. Arthritis Rheum 2002; 46: 2132-2140
11. Karassa FB, Trikalinos TA, Ioannidis JPA et al. The FcyRIIIA-F158 allele is a risk factor for the development of lupus nephritis: A meta-analysis. Kidney Int 2003; 63: 1475-1482
12. Salmon JE, Pricop L. Human receptors of immunoglobulin G: Key elements in the pathogenesis of rheumatic disease. Arthritis Rheum 2001; 44: 739-750
13. Bolland S, Ravetch JV. Spontaneous autoimmune disease in FcgRIIB deficient mice results from strain-specific epistasis. Immunity 2000; 13: 277-285
14. Kyogoku C, Dijstelbloem HM, Tsuchiya N et al. Fcy receptor gene polymorphisms in Japanese patients with systemic lupus erythematosus: contribution of FCGRIIB to genetic susceptibility. Arthritis Rheum 2002; 46: 1242-1254
15. Li X, Wu J, Carter RH et al. A novel polymorphism in the Fcg receptor IIB (CD32B) transmembrane region alters receptor signalling. Arthritis Rheum 2003; 48: 3242-3252
16. Siriboonrit U, Tsuchiya N, Sirikong M et al. Association of FcgR IIb and IIIb polymorphisms with susceptibility to systemic lupus erythematosus in Thais. Tissue Antigens 2003; 61: 374-383
17. Aitman TJ, Dong R, Vyse TJ et al. Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans. Nature 2006; 439: 851-855
18. Feuk L, Carson AR, Scherer SW. Structural variation in the human genome. Nature Rev Genet 2006; 7: 85-97
19. Gonzalez E. The influence of CLL3L1 gene-containing segmental duplications on HIV/aids susceptibility. Science 2005; 307: 1434-1440