A microplate solid scintillation counter as a radioactivity detector for high performance liquid chromatography in drug metabolism: Validation and applications

Journal of Chromatography A

Volumn 1133, Issue 1-2, 2006, Pages 184-194

  Bruin, Gerard J ^a   Waldmeier, Felix ^a   Boernsen, K Olaf ^a   Pfaar, Ulrike ^a   Gross, Gerhard ^a   Zollinger, Markus ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Animal and human ADME studies; Microplate scintillation counter; Offline HPLC radioactivity detection

Indexed keywords

ANIMAL ADME STUDIES; HUMAN ADME STUDIES; MICROPLATE SCINTILLATION COUNTERS; OFFLINE HPLC RADIOACTIVITY DETECTION;

DRUG PRODUCTS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; RADIATION DETECTORS; RADIOACTIVITY; RADIOACTIVITY MEASUREMENT;

SCINTILLATION COUNTERS;

AAE 327; AMP 397; CARBON 14; IMATINIB; TRITIUM;

ARTICLE; DRUG ABSORPTION; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG METABOLISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; ISOTOPE LABELING; LIQUID SCINTILLATION COUNTING; PRIORITY JOURNAL; RADIATION DETECTION; RADIOCHROMATOGRAPHY; SCINTILLATION COUNTING; VALIDATION STUDY;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; PHARMACEUTICAL PREPARATIONS; RADIOISOTOPES; RATS; REPRODUCIBILITY OF RESULTS; SCINTILLATION COUNTING;

ANIMALIA;

EID: 33750102850     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2006.08.020     Document Type: Article

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