The use of 96-well Scintiplates to facilitate definitive metabolism studies for drug candidates

Journal of Pharmaceutical and Biomedical Analysis

Volumn 34, Issue 3, 2004, Pages 607-617

  Nedderman, Angus N R ^a   Savage, Mark E ^a   White, Katharine L ^a   Walker, Donald K ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

96 Well Scintiplates; Mass spectrometry; Metabolite identification; Metabolite profiling; Radiochemical detection

Indexed keywords

3 [1 (1,3 BENZODIOXOL 5 YL) 2 [(2 METHOXY 4 METHYLPHENYL)SULFONAMIDO] 2 OXOETHYL] 6 (HYDROXYMETHYL) 1 METHYL 1H INDOLE; CARBON 14; DRUG METABOLITE; INDOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOTOPE LABELING; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RADIOACTIVITY; RAT;

EID: 0842281553     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(03)00575-2     Document Type: Article

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