Effect of hypercapnia on cerebral blood flow and blood volume in pigs studied by positron emission tomography

Comparative Medicine

Volumn 56, Issue 5, 2006, Pages 416-420

  Olsen, Aage K ^a   Keiding, Susanne ^a   Munk, Ole L ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; CARBON DIOXIDE; HYDROGEN; OXYGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL BLOOD; ARTICLE; BRAIN BLOOD FLOW; BRAIN BLOOD VOLUME; BRAIN TISSUE; CARBON DIOXIDE TENSION; DOMESTIC PIG; FEMALE; HYPERCAPNIA; IN VITRO STUDY; NONHUMAN; POSITRON EMISSION TOMOGRAPHY;

ANIMALS; BLOOD VOLUME; BRAIN; CARBON DIOXIDE; CEREBROVASCULAR CIRCULATION; FEMALE; HYPERCAPNIA; KINETICS; MODELS, ANIMAL; POSITRON-EMISSION TOMOGRAPHY; REGIONAL BLOOD FLOW; SWINE;

EID: 33750074135     PISSN: 15320820     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Akaike H. 1974. A new look at the statistical model identification. IEEE Trans Automat Control 19:716-723.
2. Andersen F, Watanabe H, Bjarkam C, Danielsen EH, Cumming P, DaNeX Study Group. 2005. Pig brain stereotaxic standard space: mapping of cerebral blood flow normative values and effect of MPTP-lesioning. Brain Res Bull 66:17-29.
3. Bender D, Olsen AK, Marthi MK, Smith DF, Cumming P. 2004. PET evaluation of the uptake of N-11C-methyl CP-643,051, an NK1 receptor antagonist, in the living porcine brain. Nucl Med Biol 31:699-704.
4. Bollen PJA, Hansen AK, Rasmussen HJ. 2000. The laboratory swine. Washington (DC): CRC Press.
5. Crone C. 1963. The permeability of capillaries in various organs as determined by the use of the 'indicator diffusion' method. Acta Physiol Scand 58:292-305.
6. 11C-raclopride to dopamine D-2, D-3 receptors in pig brain. Neuroimage 19:1127-1136.
7. Danielsen E, Smith DF, Poulsen PH, Østergaard L, Gee AD, Ishizu K, Venkatachalam TK, Bender D, Hansen SB, Gjedde A, Scheel-Krüger J, Møller A. 1998. Positron emission tomography of living brain in minipigs and domestic pigs. Scand J Lab Anim Sci 25 (Suppl 1):127-135.
8. Ganong WF. 1991. Review of medical physiology. 15th ed. Columbus (OH): McGraw-Hill.
9. Gjedde A. 1995. Tracer kinetics: compartmental analysis. In: Wagner H, Szabo Z, Buchanan JW, editors. Principles of nuclear medicine. 2nd ed. Philadelphia: WB Saunders. p 451-461.
10. Hino JK, Short BL, Rais-Bahrami K, Seale WR. 2000. Cerebral blood flow and metabolism during and after prolonged hypercapnia in newborn lambs. Crit Care Med 28:3505-3510.
11. Hopton P, Walsh TS, Lee A. 1999. Measurement of cerebral blood volume using near-infrared spectroscopy and indocyanine green elimination. J Appl Physiol 87:1981-1987.
12. Iversen P, Hansen DA, Bender D, Rodell A, Munk OL, Cumming P, Keiding S. 2006. Peripheral benzodiazepine receptors in the brain of patients with cirrhosis and manifest hepatic encephalopathy. Eur J Nucl Med Mol Imaging. Forthcoming.
13. 13N-ammonia during acute hepatic encephalopathy in cirrhosis measured by PET. Hepatology 43:42-50.
14. Kuschinsky W, Wahl M. 1978. Local chemical and neurogenic regulation of cerebral vascular resistance. Physiol Rev 58:656-689.
15. Lind NM, Gjedde A, Moustgaard A, Olsen AK, Jensen SB, Jakobsen S, Arnfred SM, Hansen AK, Hemmingsen RP, Cumming P. 2005. Behavioral response to novelty correlates with dopamine receptor availability in striatum of Göttingen minipigs. Behav Brain Res 164:172-177.
16. Lind NM, Olsen AK, Moustgaard A, Jensen SB, Jakobsen S, Hansen AK, Arnfred SM, Hemmingsen RP, Gjedde A, Cumming P. 2005. Mapping the amphetamine-evoked dopamine release in the brain of the Göttingen minipig. Brain Res Bull 65:1-9.
17. Marquardt DW. 1963. An algorithm for least-squares estimation of nonlinear parameters. J Soc Ind Appl Math 11:431-441.
18. Minuzzi L, Olsen AK, Bender D, Arnfred S, Grant R, Danielsen EH, Cumming P. 2005. Quantitative autoradiography of ligands for dopamine receptors and transporters in brain of Göttingen minipig: comparison with results in vivo. Synapse 59:211-219.
19. Munk OL. 2004. Hepatic metabolism of glucose analogs measured by dynamic positron emission tomography and interpreted by compartment models [PhD thesis]. Aarhus: Aarhus University.
20. Munk OL, Bass L, Feng H, Keiding S. 2003. Determination of regional flow by use of intravascular PET tracers: microvascular theory and experimental validation for pig livers. J Nucl Med 44:1862-1870.
21. 11C-NMSP binding in living pig brain. Synapse 53:222-233.
22. Neto PR, Olsen AK, Gjedde A, Watanabe H, Cumming P. 2004. MDMA-evoked changes in cerebral blood flow in living porcine brain: correlation with hyperthermia. Synapse 53:214-221.
23. 2 in porcine arterial blood. Scand J Lab Anim Sci 30:197-201.
24. Panerai RB. 1998. Assessment of cerebral pressure autoregulation in humans-a review of measurement methods. Physiol Meas 19:305-338.
25. 15O-labelled water and dynamic positron emission tomography. Med Biol Eng Comput 31:495-502.
26. 18F- fluorodeoxyglucose. J Neurosci Meth 77:199-209.
27. 15O. II. Implementation and validation. J Nucl Med 24:790-798.
28. Ramsey SC, Murphy K, Shea SA, Friston KJ, Lammertsma AA, Clark JC, Adams L, Guz A, Frackowiak RSJ. 1993. Changes in global cerebral blood blow in humans: effect on regional cerebral blood flow during a neural activation task. J Physiol 471:521-534.
29. Renkin EM. 1959. Exchangeability of tissue potassium in skeletal muscle. Am J Physiol 197:1211-1215.
30. Sicard K, Shen Q, Brevard ME, Sullivan R, Ferris CF, King JA, Duong TQ. 2003. Regional cerebral blood flow and BOLD responses in conscious and anesthetized rats under basal and hypercapnic conditions: implications for functional MRI studies. J Cereb Blood Flow Metab 23:472-481.
31. Siesjo BK. 1984. Cerebral circulation and metabolism. J Neurosurg 60:883-908.
32. Toussaint P-J, Meyer E. 2001. A linear solution for calculation of K1 and k2 maps using the two-compartment CBF model. In: Gjedde A, Hansen SB, Knudsen GM, Paulson OB, editors. Physiological imaging of the brain with PET. San Diego (CA): Academic Press. p 97-102.
33. Tsai YC, Lin SS, Lee KC, Chang CL. 1994. Cerebral effects of nitrous oxide during isoflurane-induced hypotension in the pig. Br J Anaesth 73:667-672.