Work-up-free deprotection of borane complexes of phosphines, phosphites, and phosphinites with polymer-supported amines

Synlett

Volumn , Issue 16, 2006, Pages 2585-2588

  Sayalero, Sonia ^a   Pericàs, Miquel A ^a,b  

^a INSTITUTE OF CHEMICAL RESEARCH OF CATALONIA ICIQ   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Boron; Deprotection; Ligands; Phosphorus; Supported reagents

Indexed keywords

AMINE; BORANE DERIVATIVE; LIGAND; PHOSPHINE DERIVATIVE; PHOSPHITE;

ARTICLE; CATALYSIS; CHEMICAL REACTION; DEPROTECTION REACTION; OXIDATION; PURIFICATION;

EID: 33750073230     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-950439     Document Type: Article

References (25)

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14. 2 (4 × 10 mL). The solid was dried in vacuo for 24 h at 40 °C to constant weight.
15. 3): δ = 40.6, 46.1, 52.9, 55.2, 62.8, 127.7. Anal. Found: N, 5.41; C, 84.82; H, 10.47; f = 1.93 mmol/g.
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23. P-B Bond Cleavage; General Procedure: A solution of the phosphorus-borane complex (0.025 mmol) in anhyd toluene (0.5 mL) was added to a smoothly stirred suspension of the resin (see Table 1, f = 1.93-0.86 mmol/g) in anhyd toluene (1 mL) placed in a schlenk tube under an argon atmosphere at 60 °C. The mixture was heated at 60-63 °C to complete deprotection (see Table 1) and then the solution was filtered under an argon atmosphere and the resin was washed with toluene (2 × 1 mL). Removal of the solvent in vacuo provided the pure phosphorus compound without further purification.
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