Nephron segment localization of polyoma virus large T antigen in renal allografts

Human Pathology

Volumn 37, Issue 11, 2006, Pages 1400-1406

  Meehan, Shane M ^a   Kraus, Madeleine D ^a   Kadambi, Pradeep V ^a   Chang, Anthony ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

Infection; Kidney; Large T antigen; Polyomavirus; Transplant

Indexed keywords

ALKALINE PHOSPHATASE; BIOLOGICAL MARKER; CHROMOGENIC SUBSTRATE; COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; DIAMINOBENZIDINE; EPITHELIAL MEMBRANE ANTIGEN; MONOCLONAL ANTIBODY; PARAFFIN; PEROXIDASE; VIRUS DNA; VIRUS T ANTIGEN;

ANTIBODY LABELING; ARTICLE; BLOOD ANALYSIS; BOWMAN MEMBRANE; CELLULAR DISTRIBUTION; CLINICAL OBSERVATION; COMPARATIVE STUDY; CONTROLLED STUDY; DNA DETERMINATION; FREQUENCY ANALYSIS; GRAFT INFECTION; HENLE LOOP; HUMAN; HUMAN TISSUE; KIDNEY ALLOGRAFT; KIDNEY BIOPSY; KIDNEY CORTEX; KIDNEY DISEASE; KIDNEY DISTAL TUBULE; KIDNEY EPITHELIUM; KIDNEY INFECTION; KIDNEY MEDULLA; KIDNEY PROXIMAL TUBULE; NEPHRECTOMY; NEPHRON; POLYOMA VIRUS; SAMPLE; VIRUS TRANSMISSION;

ADULT; AGED; ANTIGENS, VIRAL, TUMOR; BOWMAN CAPSULE; CA-15-3 ANTIGEN; FEMALE; GENE EXPRESSION REGULATION; HUMANS; KIDNEY; KIDNEY TRANSPLANTATION; KIDNEY TUBULES, PROXIMAL; MALE; MIDDLE AGED; MUCIN-1; NEPRILYSIN; POLYOMAVIRUS;

EID: 33750069477     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2006.06.016     Document Type: Article

References (20)

1. Ramos E., Drachenberg C.B., Papadimitriou J.C., et al. Clinical course of polyoma virus nephropathy in 67 renal transplant patients. J Am Soc Nephrol 13 (2002) 2145-2151
2. Purighalla R., Shapiro R., McAuley J., and Randhawa P.S. BK virus infection in a kidney allograft diagnosed by needle biopsy. Am J Kidney Dis 4 (1995) 671-673
3. Hirsch H.H., Knowles W., Dickenmann M., et al. Prospective study of polyomavirus type BK replication and nephropathy in renal-transplant recipients. N Engl J Med 347 (2002) 488-496
4. Randhawa P.S., Finkelstein S., Scantlebury V., et al. Human polyoma virus-associated interstitial nephritis in the allograft kidney. Transplantation 67 (1999) 103-109
5. Howell D.N., Smith S.R., Butterly D.W., et al. Diagnosis and management of polyomavirus interstitial nephritis in renal transplant recipients. Transplantation 68 (1999) 1279-1288
6. Drachenberg C.B., Beskow C.O., Cangro C.B., et al. Human polyoma virus in renal allograft biopsies: morphologic findings and correlation with urine cytology. Hum Pathol 30 (1999) 970-977
7. Nickeleit V.N., Hirsch H.H., Zeiler M., et al. Polyoma virus infection of renal allograft recipients: from latent infection to manifest disease. J Am Soc Nephrol 10 (1999) 1080-1089
8. Nickeleit V., Steiger J., and Mihatsch M.J. BK virus infection after kidney transplantation. Graft 5 (2002) S46-S57
9. Harlow E., Crawford L.V., Pim D.C., and Williamson N.M. Monoclonal antibodies specific for simian virus 40 tumor antigens. J Virol 39 (1981) 861-869
10. Cubitt C.L., and Stoner G.L. Molecular genetics of the BK virus. Graft 5 (2002) S28-S35
11. Chesters P.M., Heritage J., and McCance D.J. Persistence of DNA sequences of BK and JC virus in normal human tissues and in diseased tissues. J Infect Dis 147 (1983) 676-684
12. Baldorini R., Veggiani C., Baro D., and Monga G. Kidney and urinary tract polyoma virus infection and distribution: molecular biology investigation of 10 consecutive autopsies. Arch Pathol Lab Med 129 (2005) 69-73
13. Nickeleit V., Klimkait T., Binet I.F., et al. Testing for polyomavirus type BK in plasma to identify renal allograft recipients with viral nephropathy. N Engl J Med 342 (2000) 1309-1315
14. Nickeleit V., Singh H.K., and Mihatsch M.J. Polyomavirus nephropathy: morphology, pathophysiology, and clinical management. Curr Opin Nephrol Hypertens 12 (2003) 599-605
15. Howie A.J. Epithelial membrane antigen in normal and proteinuric glomeruli and in damaged proximal tubules. J Pathol 148 (1986) 55-60
16. McIntosh G.G., Lodge A.J., Watson P., et al. NCL-CD10-270: a new monoclonal antibody recognizing CD10 in paraffin embedded tissue. Am J Pathol 154 (1999) 77-82
17. Ivyani B., Hansen H.E., and Olsen S. Segmental localization and quantitative characteristics of tubulitis in kidney biopsies from patients undergoing acute rejection. Transplantation 56 (1993) 581-585
18. Hirsch H.H., Brennan D.C., Drachenberg C.B., et al. Polyomavirus-associated nephropathy in renal transplantation: interdisciplinary analyses and recommendations. Transplantation 79 (2005) 1277-1286
19. Drachenberg C.B., Papadimitriou J.C., Wali R., Cubitt C.L., and Ramos E. BK polyoma virus allograft nephropathy: ultrastructural features from viral cell entry to lysis. Am J Transp 3 (2003) 1383-1392
20. Meehan S.M., Kadambi P.V., Manaligod J.R., Williams J.W., Josephson M.A., and Javaid B. Polyoma virus infection of renal allografts: relationships of the distribution of viral infection, tubulointerstitial inflammation and fibrosis suggesting viral interstitial nephritis in untreated disease. Hum Pathol 36 (2005) 1256-1264