Polyoma virus infection of renal allografts: Relationships of the distribution of viral infection, tubulointerstitial inflammation, and fibrosis suggesting viral interstitial nephritis in untreated disease

Human Pathology

Volumn 36, Issue 12, 2005, Pages 1256-1264

  Meehan, Shane M ^a   Kadambi, Pradeep V ^a   Manaligod, Jose R ^a   Williams, James W ^a   Josephson, Michelle A ^a   Javaid, Basit ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

Acute rejection; Allograft nephropathy; Interstitial nephritis; Polyoma virus; T antigen

Indexed keywords

AZATHIOPRINE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PARAFFIN; PREDNISONE; RAPAMYCIN; TACROLIMUS;

ACUTE GRAFT REJECTION; ADULT; AGED; ARTICLE; BLEEDING; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTERSTITIAL NEPHRITIS; KIDNEY ALLOGRAFT; KIDNEY FIBROSIS; MALE; MORPHOLOGY; NEUTROPHIL; NONHUMAN; PLASMA CELL; POLYOMA VIRUS; POSTOPERATIVE INFECTION; SCORING SYSTEM; VIRUS INFECTION;

BIOPSY; FEMALE; FIBROSIS; GRAFT REJECTION; HUMANS; IMMUNOCOMPROMISED HOST; KIDNEY; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; NEPHRITIS, INTERSTITIAL; POLYOMAVIRUS; POLYOMAVIRUS INFECTIONS; TUMOR VIRUS INFECTIONS;

EID: 27944442364     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2005.08.026     Document Type: Article

References (30)

1. E. Ramos, C.B. Drachenberg, and J.C. Papadimitriou Clinical course of polyoma virus nephropathy in 67 renal transplant patients J Am Soc Nephrol 13 2002 2145 2151
2. R. Purighalla, R. Shapiro, J. McAuley, and P.S. Randhawa BK virus infection in a kidney allograft diagnosed by needle biopsy Am J Kidney Dis 4 1995 671 673
3. H.H. Hirsch, W. Knowles, and M. Dickenmann Prospective study of polyomavirus type BK replication and nephropathy in renal-transplant recipients N Engl J Med 347 2002 488 496
4. P.S. Randhawa, S. Finkelstein, and V. Scantlebury Human polyoma virus-associated interstitial nephritis in the allograft kidney Transplantation 67 1999 103 109
5. D.N. Howell, S.R. Smith, and D.W. Butterly Diagnosis and management of polyomavirus interstitial nephritis in renal transplant recipients Transplantation 68 1999 1279 1288
6. C.B. Drachenberg, C.O. Beskow, and C.B. Cangro Human polyoma virus in renal allograft biopsies: morphologic findings and correlation with urine cytology Hum Pathol 30 1999 970 977
7. V.N. Nickeleit, H.H. Hirsch, and M. Zeiler Polyoma virus infection of renal allograft recipients: from latent infection to manifest disease J Am Soc Nephrol 10 1999 1080 1089
8. V. Nickeleit, J. Steiger, and M.J. Mihatsch BK virus infection after kidney transplantation Graft 5 2002 S46 S57
9. M. Ahuja, E.P. Cohen, and A.M. Dayer Polyoma virus infection after renal transplantation. Use of immunostaining as a guide to diagnosis Transplantation 71 2001 896 899
10. S.V. Seshan, E. Hyjek, M. Marotta, A. Chadburn, and M. Suthanthiran Immunophenotyping of BK virus nephropathy and acute allograft rejection: potential diagnostic and prognostic markers Mod Pathol 15 2002 280A
11. A. Chang, J. Kowaleska, and A.P. Limaye CD3 and CD20 immunohistochemistry of renal transplant biopsies with polyoma-virus associated nephritis or acute allograft rejection Mod Pathol 16 2003 266A
12. S.M. Meehan, P. Domer, and M. Donohoe The clinical and pathologic implications of plasmacytic infiltrates in renal allograft biopsies Hum Pathol 32 2001 205 215
13. R.D. Poduval, P.V. Kadambi, and M.A. Josephson Implications of immunohistochemical detection of C4d along peritubular capillaries in late acute renal allograft rejection Transplantation 79 2005 228 235
14. E. Mazzucchi, A.M. Lucon, and W.C. Nahas Histologic outcome of acute cellular rejection in kidney transplantation after treatment with methylprednisolone Transplantation 67 1999 430 434
15. L.W. Gaber, L.W. Moore, A.O. Gaber, R.J. Tesi, J. Meyer, and T.J. Schroeder Correlation of histology to clinical rejection reversal: a thymoglobulin multicenter trial report Kidney Int 55 1999 2415 2422
16. D. Rush, P. Nickerson, and J. Gough Beneficial effects of treatment of early subclinical rejection: a randomized study J Am Soc Nephrol 9 1998 2129 2134
17. H. Vlaminck, B. Maes, and G. Evers Prospective study on late consequences of subclinical non-compliance with immunosuppressive therapy in renal transplant patients Am J Transplant 4 2004 1509 1513
18. B. Celik, R. Shapiro, A. Vats, and P.S. Randhawa Polyomavirus allograft nephropathy: sequential assessment of histologic viral load, tubulitis, and graft function following changes in immunosuppression Am J Transplant 3 2003 1378 1382
19. C. Drachenberg, J.C. Papadimitriou, and H.H. Hirsch Histological patterns of polyoma virus nephropathy: correlation with graft outcome and viral load Am J Transplant 4 2004 2082 2092
20. S. Rosen, W. Harmon, and A.M. Krensky Tubulointerstitial nephritis associated with polyoma virus (BK type) infection N Engl J Med 308 1983 1192 1196
21. H. Schmid, M. Burg, M. Kretzler, B. Banas, H.-J. Grone, and V. Kliem BK virus associated nephropathy in native kidneys of a heart allograft recipient Am J Transplant 5 2005 1562 1568
22. A. Milstone, R.A. Vilchez, X. Geiger, A.B. Fogo, J.S. Butel, and S. Dummer Polyomavirus simian virus 40 associated with nephropathy in a lung transplant recipient Transplantation 77 2004 1019 1024
23. O. Cubukcu-Dimopulo, A. Greco, A. Kumar, D. Karluk, K. Mittal, and J. Jagirdar BK virus infection in AIDS Am J Surg Pathol 24 2000 145 149
24. R. Boldorini, E. Omodeo-Zorini, M. Nebuloni, E. Benignini, L. Vago, and A. Ferri Lytic JC virus in the kidneys if AIDS subjects Mod Pathol 16 2003 35 42
25. S. Stracke, U. Helmchen, L. von Muller, D. Bunjes, and F. Keller Polyoma virus-associated interstitial nephritis in patient with acute myeloic leukaemia and peripheral blood stem cell transplantation Nephrol Dial Transplant 18 2003 2431 2433
26. M.A. van Gorder, P. Della Pelle, J.W. Henson, D.H. Sachs, A.B. Cosimi, and R.B. Colvin Cynomolgus polyoma virus infection Am J Pathol 154 1999 1273 1284
27. E. Harlow, L.V. Crawford, D.C. Pim, and N.M. Williamson Monoclonal antibodies specific for simian virus 40 tumor antigens J Virol 39 1981 861 869
28. C.L. Cubitt, and G.L. Stoner Molecular genetics of the BK virus Graft 5 2002 S28 S35
29. L.C. Racusen, K. Solez, and R.B. Colvin The Banff 97 working classification of renal allograft pathology Kidney Int 55 1999 713 723
30. P.J. Michaels, M.C. Fishbein, and R.B. Colvin Humoral rejection of human organ transplants Springer Semin Immunopathol 25 2003 119 140