External and internal exposure to polycyclic aromatic hydrocarbons (PAH) among workers in the production of fire-proof materials - Proposal of a biological monitoring guidance value

International Journal of Hygiene and Environmental Health

Volumn 209, Issue 6, 2006, Pages 575-580

  Preuss, Ralf ^a   Roßbach, Bernd ^b   Wilhelm, Michael ^c   Brüning, Thomas ^c   Angerer, Jürgen ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

^c RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Biological monitoring guidance values (BMGVs); Human biomonitoring; PAH; PAH metabolites; Polycyclic aromatic hydrocarbons; Urine; Workplace

Indexed keywords

1 HYDROXYPYRENE; BENZO[A]PYRENE; CREATININE; PHENANTHRENE DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON;

ADULT; AIR ANALYSIS; AIR MONITORING; ARTICLE; BIOLOGICAL MONITORING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CREATININE URINE LEVEL; EMPLOYEE; GERMANY; HUMAN; INDUSTRIAL AREA; INDUSTRIAL PRODUCTION; METABOLITE; OCCUPATIONAL CANCER; OCCUPATIONAL EXPOSURE; SAMPLING; URINALYSIS; URINE; WORK ENVIRONMENT; WORKROOM AIR;

EID: 33750049036     PISSN: 14384639     EISSN: 1618131X     Source Type: Journal    
DOI: 10.1016/j.ijheh.2006.05.005     Document Type: Article

References (21)

1. ACGIH, American Conference of Governmental Industrial Hygienists, 2005. TLVs and BEIs. Threshold Limit Values for Chemical Substances and Physical Agents & Biological Exposure Indices. Worldwide Signature Publications.
2. Armstrong B., Tremblay C., Baris D., and Theriault G. Lung cancer mortality and polynuclear aromatic hydrocarbons: a case-cohort study of aluminum production workers in Arvida, Quebec, Canada. Am. J. Epidemiol. 139 (1994) 250-262
3. Becker K., Schulz C., Kaus S., Seiwer M., and Seifert B. German Environmental Survey 1998 (GerES III): environmental pollutants in the urine of the German population. Int. J. Hyg. Environ. Health 206 (2003) 15-24
4. Boffetta P., Jourenkova N., and Gustavsson P. Cancer risk from occupational and environmental exposure to polycyclic aromatic hydrocarbons. Cancer Causes Control 8 3 (1997) 444-472
5. GerES-III, 1998. German Environmental Survey. German Federal Environmental Agency 1998. 〈http://www.umweltbundesamt.de/survey-e/us98/pak.htm〉 (accessed 5 March 2006).
6. Gundel J., Schaller K.H., and Angerer J. Occupational exposure to polycyclic aromatic hydrocarbons in a fireproof stone producing plant: biological monitoring of 1-hydroxypyrene, 1-, 2-, 3- and 4-hydroxyphenanthrene, 3-hydroxybenz(a)anthracene and 3-hydroxybenzo(a)pyrene. Int. Arch. Occup. Environ. Health 73 (2000) 270-274
7. Heudorf U., and Angerer J. Urinary monohydroxylated phenanthrenes and hydroxypyrene - the effects of smoking habits and changes induced by smoking on monooxygenase-mediated metabolism. Int. Arch. Occup. Environ. Health 74 (2001) 177-183
8. HSE, Health and Safety Executive, 2003. Toxic Substances Bulletin, issue 52, September 2003. 〈http://www.hse.gov.uk/toxicsubstances/issue52.htm〉 (accessed 5 March 2006).
9. Jongeneelen F.J. Benchmark guideline for urinary 1-hydroxypyrene as biomarker of occupational exposure to polycyclic aromatic hydrocarbons. Ann. Occup. Hyg. 45 (2001) 3-13
10. Lemm F., Wilhelm M., and Roos P.H. Occupational exposure to polycyclic aromatic hydrocarbons suppresses constitutive expression of CYP1B1 on the transcript level in human leukocytes. Int. J. Hyg. Environ. Health 207 (2004) 325-335
11. Lintelmann J., and Angerer J. PAH metabolites. In: Angerer J., and Schaller K.H. (Eds). Analyses of Hazardous Substances in Biological Materials vol. 6 (1999), Wiley-VCH, Weinheim 163-187
12. Lloyd J.W. Long-term mortality study of steelworkers. V. Respiratory cancer in coke plant workers. J. Occup. Med. 13 (1971) 53-68
13. Marczynski B., Rihs H.P., Rossbach B., Holzer J., Angerer J., Scherenberg M., Hoffmann G., Bruning T., and Wilhelm M. Analysis of 8-oxo-7,8-dihydro-2'-deoxyguanosine and DNA strand breaks in white blood cells of occupationally exposed workers: comparison with ambient monitoring, urinary metabolites and enzyme polymorphisms. Carcinogenesis 23 (2002) 273-281
14. Marczynski B., Preuss R., Mensing T., Angerer J., Seidel A., El Mourabit A., Wilhelm M., and Bruning T. Genotoxic risk assessment in white blood cells of occupationally exposed workers before and after alteration of the polycyclic aromatic hydrocarbon (PAH) profile in the production material: comparison with PAH air and urinary metabolite levels. Int. Arch. Occup. Environ. Health 78 (2005) 97-108
15. Mastrangelo G., Fadda E., and Marzia V. Polycyclic aromatic hydrocarbons and cancer in man. Environ. Health Perspect. 104 (1996) 1166-1170
16. Mensing T., Marczynski B., Engelhardt B., Wilhelm M., Preuss R., Kappler M., Angerer J., Kafferlein H.U., Scherenberg M., Seidel A., and Bruning T. DNA adduct formation of benzo[a]pyrene in white blood cells of workers exposed to polycyclic aromatic hydrocarbons. Int. J. Hyg. Environ. Health 208 (2005) 173-178
17. NIOSH. Polynuclear aromatic hydrocarbons by HPLC. In: Cassinelli M.E., and O′Connor P.E. (Eds). NIOSH Manual of Analytical Methods (NMAM). fourth ed (1994), National Institute for Occupational Safety and Health, Washington, DC
18. Preuss R., Drexler H., Bottcher M., Wilhelm M., Bruning T., and Angerer J. Current external and internal exposure to naphthalene of workers occupationally exposed to polycyclic aromatic hydrocarbons in different industries. Int. Arch. Occup. Environ. Health 78 (2005) 355-362
19. Scherer G., and Meger-Kossien I. Cotinine. In: Angerer J., and Schaller K.H. (Eds). Analyses of Hazardous Substances in Biological Materials vol. 7 (2001), Wiley-VCH, Weinheim 171-189
20. Taussky H.H. A micro-colorimetric determination of creatinine in urine by the Jaffé reaction. J. Biol. Chem. 208 (1954) 853-861
21. Tremblay C., Armstrong B., Theriault G., and Brodeur J. Estimation of risk of developing bladder cancer among workers exposed to coal tar pitch volatiles in the primary aluminium industry. Am. J. Ind. Med. 27 (1995) 335-348