Amiloride attenuates glycine-induced currents in cultured neurons of rat inferior colliculus

Biochemical and Biophysical Research Communications

Volumn 350, Issue 4, 2006, Pages 900-904

  Tang, Zheng Quan ^a   Lu, Yun Gang ^a   Zhou, Ke Qing ^a   Xu, Tian Le ^b   Chen, Lin ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b Chinese Academy of Sciences   (China)

Author keywords

Amiloride; Cell culture; Glycine receptor; Inferior colliculus; Rat; Whole cell patch clamp

Indexed keywords

AMILORIDE; GLYCINE;

AMPLITUDE MODULATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BLOOD BRAIN BARRIER; BRAIN FUNCTION; BRAIN TUMOR; CELL ACTIVITY; CEREBROSPINAL FLUID; CONCENTRATION RESPONSE; CONSTANTS AND COEFFICIENTS; CONTROLLED STUDY; DRUG BINDING; DRUG EFFECT; DRUG RECEPTOR BINDING; ELECTRIC CURRENT; IC 50; INFERIOR COLLICULUS; INHIBITION KINETICS; NERVE CELL CULTURE; NERVE CELL MEMBRANE; NEWBORN; NONHUMAN; PATCH CLAMP; PERFUSION; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; RECORDING; VOLTAGE CLAMP;

AMILORIDE; ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; GLYCINE; INFERIOR COLLICULI; INFERIOR COLLICULUS; MEMBRANE POTENTIALS; NEURONS; RATS; RATS, WISTAR;

EID: 33750039342     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.09.110     Document Type: Article

References (29)

1. Akaike N., and Ueno S. Proton-induced current in neuronal cells. Prog. Neurobiol. 43 (1994) 73-83
2. Bubien J.K., Keeton D.A., Fuller C.M., Gillespie G.Y., Reddy A.T., Mapstone T.B., and Benos D.J. Malignant human gliomas express an amiloride-sensitive Na+ conductance. Am. J. Physiol. 276 (1999) C1405-C1410
3. Fisher J.L. Amiloride inhibition of gamma-aminobutyric acid(A) receptors depends upon the alpha subunit subtype. Mol. Pharmacol. 61 (2002) 1322-1328
4. Frelin C., Barbry P., Vigne P., Chassande O., Cragoe Jr. E.J., and Lazdunski M. Amiloride and its analogs as tools to inhibit Na+ transport via the Na+ channel, the Na+/H+ antiport and the Na+/Ca2+ exchanger. Biochimie 70 (1988) 1285-1290
5. Gao J., Duan B., Wang D.G., Deng X.H., Zhang G.Y., Xu L., and Xu T.L. Coupling between NMDA receptor and acid-sensing ion channel contributes to ischemic neuronal death. Neuron 48 (2005) 635-646
6. Garritsen A., Ijzerman A.P., Beukers M.W., Cragoe Jr. E.J., and Soudijn W. Interaction of amiloride and its analogues with adenosine A1 receptors in calf brain. Biochem. Pharmacol. 40 (1990) 827-834
7. Hoare S.R., Coldwell M.C., Armstrong D., and Strange P.G. Regulation of human D(1), d(2(long)), d(2(short)), D(3) and D(4) dopamine receptors by amiloride and amiloride analogues. Br. J. Pharmacol. 130 (2000) 1045-1059
8. Hosomi H., Mori M., Amatsu M., and Okada Y. GABA-activated conductance in cultured rat inferior colliculus neurons. J. Neurophysiol. 77 (1997) 994-1002
9. Inomata N., Ishihara T., and Akaike N. Effects of diuretics on GABA-gated chloride current in frog isolated sensory neurones. Br. J. Pharmacol. 93 (1988) 679-683
10. Iwasa K.H., Mizuta K., Lim D.J., Benos D.J., and Tachibana M. Amiloride-sensitive channels in marginal cells in the stria vascularis of the guinea pig cochlea. Neurosci. Lett. 172 (1994) 163-166
11. Jorgensen F., and Ohmori H. Amiloride blocks the mechano-electrical transduction channel of hair cells of the chick. J. Physiol. 403 (1988) 577-588
12. Joris L., Krouse M.E., Hagiwara G., Bell C.L., and Wine J.J. Patch-clamp study of cultured human sweat duct cells: amiloride-blockable Na+ channel. Pflugers Arch. 414 (1989) 369-372
13. Kleyman T.R., and Cragoe Jr. E.J. Amiloride and its analogs as tools in the study of ion transport. J. Membr. Biol. 105 (1988) 1-21
14. Lane J.W., McBride Jr. D.W., and Hamill O.P. Ionic effects on amiloride block of the mechanosensitive channel in Xenopus oocytes. Br. J. Pharmacol. 108 (1993) 116-119
15. Li Y., Li Y.F., and Xu T.L. Amiloride inhibition of glycinergic miniature IPSCs in mechanically dissociated rat spinal neurons. Neurosci. Lett. 349 (2003) 17-20
16. Li Y.F., Li Y., and Xu T.L. Inhibition of glycine response by amiloride in rat spinal neurons. Neurosci. Lett. 345 (2003) 173-176
17. Malosio M.L., Marqueze-Pouey B., Kuhse J., and Betz H. Widespread expression of glycine receptor subunit mRNAs in the adult and developing rat brain. Embo. J. 10 (1991) 2401-2409
18. Mizuta K., Iwasa K.H., Tachibana M., Benos D.J., and Lim D.J. Amiloride-sensitive Na+ channel-like immunoreactivity in the luminal membrane of some non-sensory epithelia of the inner ear. Hear. Res. 88 (1995) 199-205
19. Murase K., Randic M., Shirasaki T., Nakagawa T., and Akaike N. Serotonin suppresses N-methyl-d-aspartate responses in acutely isolated spinal dorsal horn neurons of the rat. Brain Res. 525 (1990) 84-91
20. Murdoch D.L., Forrest G., Davies D.L., and McInnes G.T. A comparison of the potassium and magnesium-sparing properties of amiloride and spironolactone in diuretic-treated normal subjects. Br. J. Clin. Pharmacol. 35 (1993) 373-378
21. Nagata K., Duggan A., Kumar G., and Garcia-Anoveros J. Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing. J. Neurosci. 25 (2005) 4052-4061
22. Ong J., and Kerr D.I. Suppression of GABAB receptor function in rat neocortical slices by amiloride. Eur. J. Pharmacol. 260 (1994) 73-77
23. Piechotta K., Weth F., Harvey R.J., and Friauf E. Localization of rat glycine receptor alpha1 and alpha2 subunit transcripts in the developing auditory brainstem. J. Comp. Neurol. 438 (2001) 336-352
24. Quinn D., Du H.K., Thompson B.T., Garg H.G., and Hales C.A. Effect of dimethyl amiloride on chronic hypoxic pulmonary hypertension in rats. Chest 114 (1998) 69S-70S
25. Rusch A., Kros C.J., and Richardson G.P. Block by amiloride and its derivatives of mechano-electrical transduction in outer hair cells of mouse cochlear cultures. J. Physiol. 474 (1994) 75-86
26. Sipos E.P., and Brem H. Local anti-angiogenic brain tumor therapies. J. Neurooncol. 50 (2000) 181-188
27. Tang C.M., Presser F., and Morad M. Amiloride selectively blocks the low threshold (T) calcium channel. Science 240 (1988) 213-215
28. Ugawa S., Ueda T., Ishida Y., Nishigaki M., Shibata Y., and Shimada S. Amiloride-blockable acid-sensing ion channels are leading acid sensors expressed in human nociceptors. J. Clin. Invest. 110 (2002) 1185-1190
29. Xu H., Gong N., Chen L., and Xu T.L. Sodium salicylate reduces gamma aminobutyric acid-induced current in rat spinal dorsal horn neurons. Neuroreport 16 (2005) 813-816