Desymmetrization of substituted 1,3-diketones: A formal synthesis of (+)-stemoamide

Synlett

Volumn , Issue 16, 2006, Pages 2664-2666

  Bogliotti, Nicolas ^a   Dalko, Peter I ^a   Cossy, Janine ^a  

^a CNRS   (France)

Author keywords

Alkaloids; Desymmetrization; Reduction; Stereoselective synthesis

Indexed keywords

1,3 DIKETONE DERIVATIVE; AMIDE; KETONE DERIVATIVE; STEMOAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL REACTION; REDUCTION; STEREOCHEMISTRY; SYNTHESIS;

EID: 33750037652     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-951475     Document Type: Article

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29. The spectral data of compound 10 were in agreement with those previously reported by Khono and Narasaka (see ref. 4a), thus confirming the relative configuration of the three contiguous stereocenters.
30. Compound 10 was obtained in seven steps with an overall yield of 0.88%.