Phenotype and genotype: Perspectives for peritoneal dialysis patients

Nephrology Dialysis Transplantation

Volumn 21, Issue 11, 2006, Pages 3018-3022

  Goffin, Eric ^a   Devuyst, Olivier ^a  

^a UNIVERSITY OF LOUVAIN MEDICAL SCHOOL   (Belgium)

Author keywords

Genetic variants; Individualized medicine; Peritoneal membrane; Polymorphisms; Small solute transport; Ultrafiltration

Indexed keywords

ALBUMIN; ALPHA 2 MACROGLOBULIN; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; AQUAPORIN 1; CREATININE; CYTOSINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; GUANINE; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; NITRIC OXIDE; PLASMINOGEN ACTIVATOR INHIBITOR 1; SODIUM; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN;

AGE; COMORBIDITY; CONCENTRATION (PARAMETERS); DIABETES MELLITUS; DIABETIC NEPHROPATHY; DIABETIC RETINOPATHY; DIALYSATE; ETHNIC DIFFERENCE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE PHENOTYPE CORRELATION; HUMAN; HYDRAULIC CONDUCTIVITY; HYPOALBUMINEMIA; KIDNEY FAILURE; MEMBRANE PERMEABILITY; MEMBRANE TRANSPORT; MORBIDITY; MORTALITY; NONHUMAN; NOTE; OSMOSIS; PERITONEAL DIALYSIS; PERITONITIS; POROSITY; PRIORITY JOURNAL; SEX DIFFERENCE; SOLUTE; SURVIVAL RATE; TREATMENT FAILURE; ULTRAFILTRATION; VARIABLE NUMBER OF TANDEM REPEAT;

BIOLOGICAL TRANSPORT; GENOTYPE; HUMANS; PERITONEAL DIALYSIS; PERITONEAL DISEASES; PERITONEUM; PHENOTYPE;

EID: 33750032330     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfl514     Document Type: Note

References (26)

1. Rippe B, Stelin G, Haraldsson B. Computer simulations of peritoneal fluid transport in CAPD. Kidney Int 1991; 40: 315-325
2. Ni J, Verbavatz JM, Rippe A et al. Aquaporin-1 plays an essential role in water permeability and ultrafiltration during peritoneal dialysis. Kidney Int. 2006; 69: 1518-1525
3. Twardowski ZJ, Nolph KD, Khanna R et al. Peritoneal Equilibration Test. Perit Dial Bull 1987; 7: 138-147
4. ISPD Ad hoc Committee on Ultrafiltration Management in Peritoneal Dialysis.Perit Dial Int 2000; 20 [Suppl 4]: S3-S4
5. Van Biesen W, Carlsson O, Bergia R et al. Personal dialysis capacity (PDC™) test: A multicentre clinical study. Nephrol Dial Transplant 2003; 18: 788-796
6. Davies SJ. Peritoneal solute transport - we know it is important, but what is it ? Nephrol Dial Transplant 2000; 15: 1120-1123
7. Churchill DN, Thorpe KE, Nolph KD et al. Increased peritoneal membrane transport is associated with decreased patient and technique survival for continuous peritoneal dialysis patients. The Canada-USA (CANUSA) Peritoneal Dialysis Study Group. J Am Soc Nephrol 1998; 9: 1285-1292
8. Rumpsfeld M, McDonald SP, Jonhson DW. Higher peritoneal transport status is associated with higher mortality and technique failure in the Australian and New Zealand peritoneal dialysis patient populations. J Am Soc Nephrol 2006; 17: 271-278
9. Davies SJ. Longitudinal relationship between solute transport and ultrafiltration capacity in peritoneal dialysis patients. Kidney Int 2004; 66: 2437-2445
10. Rumpsfeld M, McDonald SP, Purdie DM, Collins J, Johnson DW. Predictors of baseline peritoneal transport status in Australian and New Zealand peritoneal dialysis patients. Am J Kidney Dis 2004; 43: 492-501
11. Selgas R, Bajo MA, Cirugeda A et al. Ultrafiltration and small solute transport at initiation of PD: Questioning the paradigm of peritoneal function. Perit Dial Int 2005; 25: 68-76
12. Gillerot G, Goffin E, Michel C et al. Genetic and clinical factors influence the baseline permeability of the peritoneal membrane. Kidney Int 2005; 67: 2477-2487
13. Clerbaux G, Francart J, Wallemacq P, Robert A, Goffin E. Evaluation of peritoneal transport properties at onset of peritoneal dialysis and longitudinal follow-up. Nephrol Dial Transplant 2006; 21: 1032-1039
14. Margetts P, Churchill DN. Acquired ultrafiltration dysfunction in peritoneal dialysis patients. J Am Soc Nephrol 2002; 13: 2787-2794
15. Miyata T, Devuyst O, Kurokawa K, van Ypersele de Strihou C. Toward better dialysis compatibility: Advances in the biochemistry and pathophysiology of the peritoneal membranes. Kidney Int 2002; 61: 375-386
16. Gillerot G, Devuyst O. Changes in the peritoneal membrane with peritoneal dialysis: Molecular mechanisms. Clin Nephrol 2003; 60: 1-6
17. Szeto CC, Poon P, Szeto CY, Wong TY, Lai KB, Li PK. Plasminogen activator inhibitor-1 4G/5G genetic polymorphism does not affect peritoneal transport characteristic. Am J Kidney Dis 2002; 39: 1061-1067
18. Wong TY, Szeto CC, Szeto CY, Lai KB, Chow KM, Li PK. Association of ENOS polymorphism with basal peritoneal membrane function in uremic patients. Am J Kidney Dis 2003; 42: 781-786
19. Szeto CC, Chow KM, Poon P, Szeto CY, Wong TY, Li PK. Genetic polymorphism of VEGF: Impact on longitudinal change of peritoneal transport and survival of peritoneal dialysis patients. Kidney Int 2004; 65: 1947-1955
20. Ni J, Moulin P, Gianello P et al. Mice lacking endothelial nitric oxide synthase are protected against functional and structural modifications induced by acute peritonitis. J Am Soc Nephrol 2003; 14: 3205-3216
21. Pecoits-Filho R, Araujo MR, Lindholm B et al. Plasma and dialysate IL-6 and VEGF concentrations are associated with high peritoneal solute transport rate. Nephrol Dial Transplant 2002; 17: 1480-1486
22. Combet S, Miyata T, Moulin P, Pouthier D, Goffin E, Devuyst O. Vascular proliferation and enhanced expression of endothelial nitric oxide synthase in human peritoneum exposed to long-term peritoneal dialysis. J Am Soc Nephrol 2000; 11: 717-728
23. Jones SA, Horiuchi S, Topley N et al. The soluble interleukin 6 receptor: Mechanisms of production and implications in disease. FASEB J 2001; 15: 43-58
24. Persu A, Duyme M, Pirson Y et al. Comparison between siblings and twins supports a role for modifier genes in ADPKD. Kidney Int 2004; 66: 2132-2136
25. Taylor JG, Choi EH, Foster CB, Chanock SJ. Using genetic variation to study human disease. Trends Mol Med 2001; 7: 507-512
26. Ioannidis JPA. Genetic associations: False or true? Trends Mol Med 2003; 9: 135-138