Timing of FSH administration for ovarian stimulation in normo-ovulatory women: Comparison of an early or a mid follicular phase initiation of a short-term treatment

Human Reproduction

Volumn 21, Issue 11, 2006, Pages 2941-2947

  Cedrin Durnerin, Isabelle ^a   Massin, N ^a   Galey Fontaine, J ^a   Bry Gauillard, H ^a   Roger, M ^b   Lahlou, N ^b   Hugues, J N ^b  

^a UNIVERSITÉ PARIS 13   (France)

^b HÔPITAL SAINT VINCENT DE PAUL   (France)

Author keywords

Follicle development; FSH administration; Ovarian stimulation; Ovulatory women

Indexed keywords

ESTRADIOL; FOLLITROPIN; LUTEINIZING HORMONE; PROGESTERONE; RECOMBINANT FOLLITROPIN;

ADULT; ARTICLE; CELL COUNT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG DOSE REGIMEN; DRUG WITHDRAWAL; FEMALE; FEMALE INFERTILITY; FERTILIZATION IN VITRO; FOLLICULAR PHASE; HORMONE DETERMINATION; HUMAN; MAJOR CLINICAL STUDY; MULTIPLE PREGNANCY; OVARY CYCLE; OVARY FOLLICLE CELL; OVARY FOLLICLE DEVELOPMENT; OVARY HYPERSTIMULATION; OVULATION; OVULATION INDUCTION; RANDOMIZED CONTROLLED TRIAL; TIME; TRANSVAGINAL ECHOGRAPHY; TREATMENT DURATION;

EID: 33750010987     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/del259     Document Type: Article

References (25)

1. Balasch J, Ballesca JL, Pimentel C, Creus M, Fabregues F and Vanrell JA (1994) Late low-dose pure follicle stimulating hormone for ovarian stimulation in intra-uterine insemination cycles. Hum Reprod 9,1863-1866.
2. Christin-Maitre S, Hugues JN and Recombinant FSH Study Group (2003) A comparative randomized multicentric study comparing the step-up versus step-down protocol in polycystic ovary syndrome. Hum Reprod 18,1626-1631.
3. Dickey RP, Taylor SN, Lu PY, Sartor BM, Rye PH and Pyrzak R (2001) Relationship of follicle numbers, estradiol levels to multiple implantation in 3608 intrauterine insemination cycles. Fertil Steril 75,69-78.
4. Dickey RP, Taylor SN, Lu PY, Sartor BM, Rye PH and Pyrzak R (2005) Risk factors for high-order multiple pregnancy and multiple birth after controlled ovarian hyperstimulation: Results of 4062 intrauterine insemination cycles. Fertil Steril 83,671-683.
5. Fauser BCJM, Devroey P and Macklon NS (2005) Multiple birth resulting from ovarian stimulation for subfertility treatment. Lancet 365,1807-1816.
6. Gleicher N, Oleske DM, Tur-Kaspa I, Vidali A and Karande V (2000) Reducing the risk of high-order multiple pregnancy after ovarian stimulation with gonadotropins. N Engl J Med 343,2-7.
7. Goverde AJ, Lambalk CB, McDonnell J, Schats R, Homburg R and Vermeiden JPW (2005) Further considerations on natural or mild hyperstimulation cycles for intrauterine insemination treatment: Effects on pregnancy and multiple pregnancy rates. Hum Reprod 20,3141-3146.
8. Guzick DS, Carson SA, Coutifaris C, Overstreet JW, Factor-Litvak P, Steinkampf MP, Hill JA, Mastroianni L, Buster JE, Nakajima ST et al. (1999) Efficacy of superovulation and intrauterine insemination in the treatment of infertility. National Cooperative Reproductive Medicine Network. N Engl J Med 340,177-183.
9. Hohmann FP, Laven JSE, de Jong FH, Eijkemans MJC and Fauser BCJM (2001) Low dose exogenous FSH initiated during the early, mild or late follicular phase can induce multiple dominant follicle development. Hum Reprod 16,846-854.
10. Homburg R and Howles CM (1999) Low-dose FSH therapy for anovulatory infertility associated with polycystic ovary syndrome: Rationale, results, reflections and refinements. Hum Reprod Update 5,493-499.
11. Hughes EG, Collins JA and Gunby J (1998) A randomised controlled trial of three low-dose gonadotrophin protocols for unexplained infertility. Hum Reprod 6,1527-1531.
12. Hugues JN, Cedrin-Durnerin I, Avril C, Bulwa S, Hervé F and Uzan M (1996) Sequential step-up and step-down dose regimen: An alternative method for ovulation induction with follicle stimulating hormone in polycystic ovary syndrome. Hum Reprod 11,2581-2584.
13. Lahlou N, Chabbert-Buffet N, Christin-Maitre S, Le Nestour E, Roger M and Bouchard P (1999) Main inhibitor of follicle stimulating hormone in the luteal-follicular transition: Inhibin A, oestradiol, or inhibin B? Hum Reprod 14,1190-1193.
14. Lolis DE, Tsolas O and Messinis I (1995) The follicle-stimulating hormone threshold level for follicle maturation in superovulated cycles. Fertil Steril 63,1272-1277.
15. Papageorgiou TC, Guibert J, Savale M, Goffinet F, Fournier C, Merlet F, Janssens Y and Zorn JR (2004) Low dose recombinant FSH treatment may reduce multiple gestations caused by controlled ovarian hyperstimulation and intrauterine insemination. BJOG 111,1277-1282.
16. Ragni G, Alagna F, Brigante C, Riccaboni A, Colombo M, Somigliana E and Crosignani PG (2004) GnRH antagonists and mild ovarian stimulation for intrauterine insemination: A randomized study comparing different gonadotrophin dosages. Hum Reprod 19,54-58.
17. Richmond JR, Deshpande N, Lyall H, Yates RWS and Fleming R (2005) Follicular diameters in conception cycles with and without multiple pregnancy after stimulated ovulation induction. Hum Reprod 20,756-760.
18. Schipper I, Hop WCJ and Fauser BCJM (1998a) The follicle-stimulating hormone (FSH) threshold/window concept examined by different interventions with exogenous FSH during the follicular phase of the normal menstrual cycle: Duration rather than magnitude of FSH increase affects follicle development. J Clin Endocrinol Metab 83,1292-1298.
19. Schipper I, de Jong FH and Fauser BCJM (1998b) Lack of correlation between maximum early follicular phase serum follicle stimulating hormone concentrations and menstrual cycle characteristics in women under the age of 35 years. Hum Reprod 13,1442-1448.
20. Sengoku K, Tamate K, Takaoka Y, Horikawa M, Goishi K, Komori H, Okada R, Tsuchiya K and Ishikawa M (1999) The clinical efficacy of low-dose step-up follicle stimulating hormone administration for treatment of unexplained infertility. Hum Reprod 14,349-353.
21. Silverberg KM, Olive DL, Burns WN, Rye PH, Lu PY and Pyrzark R (1991) Follicular size at the time of human chorionic gonadotropin administration predicts ovulation outcome in human menopausal gonadotropin-stimulated cycles. Fertil Steril 56,296-300.
22. Stone BA, Vargyas JM, Ringler GE, Stein AL and Marss RP (1999) Determinants of the outcome of intrauterine insemination: Analysis of outcomes of 9963 consecutive cycles. Am J Obstet Gynecol 180,1522-1534.
23. Tur R, Barri PN, Coroleu B, Buxaderas R, Martinez F and Balasch J (2001) Risk factors for high-order multiple implantation after ovarian stimulation with gonadotrophins: Evidence from a large series of 1878 consecutive pregnancies in a single centre. Hum Reprod 16,2124-2129.
24. Tur R, Barri PN, Coroleu B, Buxaderas R, Parera N and Balasch J (2005) Use of a prediction model for high-order multiple implantation after ovarian stimulation with gonadotrophins. Fertil Steril 83,116-121.
25. Van Rumste MME, den Hartog JE, Dumoulin JCM, Evers JHL and Land JA (2006) Is controlled ovarian stimulation in intrauterine insemination an acceptable therapy in couples with unexplained non-conception in the perspective of multiple pregnancies? Hum Reprod 21,701-704.