Tacrolimus ointment does not affect the immediate response to vaccination, the generation of immune memory, or humoral and cell-mediated immunity in children

Archives of Disease in Childhood

Volumn 91, Issue 11, 2006, Pages 905-910

  Hofman, T ^a   Cranswick, N ^b   Kuna, P ^c   Boznanski, A ^d   Latos, T ^e   Gold, M ^f   Murrell, D F ^g   Gebauer, K ^h   Behre, U ⁱ   Machura, E ^j   Olafsson J ⁱ   Szalai, Z ^k  

^a Allergy Centre   (Poland)

^b ROYAL CHILDREN'S HOSPITAL   (Australia)

^c N Barlicki University Hospital No 1 of Medical University of Lodz   (Poland)

^d WROCLAW MEDICAL UNIVERSITY   (Poland)

^e Centrum Pulmonologii Dzieciecej   (Poland)

^f WOMEN S AND CHILDREN S HOSPITAL   (Australia)

^g UNIVERSITY OF NEW SOUTH WALES   (Australia)

^h Fremantle Dermatology   (Australia)

ⁱ Slaskie Centrum Pediatrii ^*  (Iceland)

^j Oddzial Pulmonologii i Alergologii   (Poland)

^k HEIM PÁL CHILDREN S HOSPITAL   (Hungary)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AC VAX; HYDROCORTISONE; HYDROCORTISONE ACETATE; HYDROCORTISONE BUTYRATE; MENINGOCOCCUS VACCINE; POLYSACCHARIDE VACCINE; TSUKUBAENOLIDE;

ANTIBODY TITER; APPLICATION SITE BURNING; APPLICATION SITE ERYTHEMA; APPLICATION SITE INFECTION; APPLICATION SITE PRURITUS; APPLICATION SITE RASH; ARTICLE; ATOPIC DERMATITIS; CELLULAR IMMUNITY; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE EXACERBATION; ECZEMA; HUMAN; HUMORAL IMMUNITY; IMMUNE RESPONSE; MAJOR CLINICAL STUDY; MENINGOCOCCOSIS; MULTICENTER STUDY; OINTMENT; PATIENT COMPLIANCE; PRIORITY JOURNAL; PRURITUS; RANDOMIZED CONTROLLED TRIAL; SKIN BURNING SENSATION; SKIN PAIN; TREATMENT RESPONSE; VACCINATION;

ADMINISTRATION, TOPICAL; ANTIGENS, CD; CHILD; CHILD, PRESCHOOL; DERMATITIS, ATOPIC; DOUBLE-BLIND METHOD; FEMALE; HUMANS; IMMUNITY, CELLULAR; IMMUNOGLOBULIN ISOTYPES; IMMUNOLOGIC MEMORY; IMMUNOSUPPRESSIVE AGENTS; MALE; MENINGOCOCCAL INFECTIONS; MENINGOCOCCAL VACCINES; NEISSERIA MENINGITIDIS, SEROGROUP C; TACROLIMUS;

EID: 33749992479     PISSN: 00039888     EISSN: 14682044     Source Type: Journal    
DOI: 10.1136/adc.2006.094276     Document Type: Article

References (26)

1. Leung DYM. Atopic dermatitis: new insights and opportunities for therapeutic intervention. J Allergy Clin Immunol 2000;105:860-76.
2. Laughter D, Istvan JA, Tofte SJ, et al. The prevalence of atopic dermatitis in Oregon schoolchildren. J Am Acad Dermatol 2000;43:649-55.
3. Graham-Brown RAC. Atopic dermatitis: predictions, expectations and outcomes. J Am Acad Dermatol 2001;45:561-3.
4. Bos JD, Kapsenberg ML, Sillevis Smitt JH. Pathogenesis of atopic eczema, Lancet 1994;343:1338-41.
5. Kapp A. The role of eosinophils in the pathogenesis of atopic dermatitis - eosinophil granule proteins as markers of disease activity. Allergy 1993;48:1-5.
6. Rubins A, Gutmane R, Valdmane N, et al. Pharmacokinetics of 0.1% tacrolimus ointment after first and repeated application to adults with moderate to severe atopic dermatitis. J Invest Dermatol 2005;125:68-71.
7. Harper J, Smith C, Rubins A, et al. A multicenter study of the pharmacokinetics of tacrolimus ointment after first and repeated application to children with atopic dermatitis. J Invest Dermatol 2005;124:695-9.
8. Billich A, Aschauer H, Aszodi A, et al. Percutaneous absorption of drugs used in atopic eczema: pimecrolimus permeates less through skin than corticosteroids and tacrolimus. Int J Pharm 2004;269:29-35.
9. Staab D, Pariser D, Gottiieb AB, et al. Low systemic absorption and good tolerability of pimecrolimus, administered as 1% cream (Elidel) in infants with atopic dermatitis-a multicenter, 3-week, open-label study. Pediatr Dermatol 2005;22:465-71.
10. Ochs HD. Steroids and immunizations. Pediatr Infect Dis J 1994;13:760.
11. Hanania NA, Sockrider M, Castro M, et al. Immune response to influenza vaccination in children and adults with asthma: effect of corticosteroid therapy. J Allergy Clin Immunol 2004;113:717-24.
12. Verstroeten T, Jumaan AO, Mulloly JP, et al. A retrospective cohort study of the association of varicella vaccine failure with asthma, steroid use, age at vaccination, and measles-mumps-rubella vaccination. Pediatrics 2003;112:98-103.
13. Lahood N, Emerson SS, Kumar P, et al. Antibody levels and response to pneumococcal vaccine in steroid-dependent asthma. Ann Allergy 1993;70:289-94.
14. Papp KA, Breuer K, Meuerer M, et al. Long-term treatment of atopic dermatitis with pimecrolimus cream 1% does not interfere with the development of protective antibodies after vaccination. J Am Acad Dermatol 2005;52:247-53.
15. Stiehm ER, Roberts RL, Kaplan MS, et al. Pneumococcal seroconversion after vaccination for children with atopic dermatitis treated with tacrolimus ointment. J Am Acad Dermatol 2005;53:206-13.
16. Hanifin JM, Rajka G. Diagnostic features of otopic dermatitis. Acta Dermatol Venereol (Stockh) 1980;92(Suppl 144):44-7.
17. Rajka G, Langeland T. Grading of the severity of atopic dermatitis. Acta Dermatol Venereol (Stockh) 1989;144(Suppl):13-14.
18. Borrow R, Andrews N, Goldblatt D, et al. Serological basis for use of meningococcal serogroup C conjugate vaccines in the United Kingdom: reevaluation of correlates of protection. Infect Immun 2001;69:1568-73.
19. Richmond P, Goldblolf D, Fusco PC, et al. Safety and immunogenicity of a new Neisseria meningitidis C-tetanus toxoid conjugate vaccine in healthy adulls. Vaccine 2000;18:641-6.
20. Andrews N, Borrow R, Miller E. Validation of serological correlate of protection for meningococcal C conjugate vaccine by using efficacy estimates from postlicensure surveillance in England. Clin Diagn Lab Immunol 2003;10:780-6.
21. Richmond P, Borrow R, Goldlatt D, et al. Ability of 3 different meningococcal C conjugate vaccines to induce immunologic memory after a single dose in UK toddlers. J Infect Dis 2001;183:160-3.
22. Borrow R, Goldblatt D, Andrews N, et al. Antibody persistence and immunological memory at age 4 years after meningococcal group C conjugate vaccination in children in the United Kingdom. J Infect Dis 2002;186:1353-7.
23. Machin D, Campbell MJ. Statistical tables for the design of clinical trials. Oxford: Blackwell Scientific, 1987.
24. Newcombe RG. Statistical applications in orthodontics - part II. Confidence intervals for proportions and their differences. J Orthod 2004;27:339-40.
25. Paller A, Eichenfeld LF, Leung DYM, et al. A 12-week study of tacrolimus ointment for the treatment of atopic dermatitis in pediatric patients. J Am Acad Dermatol 2001;44:47-57.
26. Reitamo S, Harper J, Bos JD, et al. 0.03% tacrolimus ointment applied once or twice daily is more efficacious than 1% hydrocortisone acetate in children with moderate to severe atopic dermatitis: result of a randomized double-blind controlled trial. Br J Dematol 2004;150:554-62.