Fulminant methicillin-sensitive Staphylococcus aureus infection in a healthy adolescent, highlighting 'Panton-Valentine leucocidin syndrome'

Internal Medicine Journal

Volumn 36, Issue 11, 2006, Pages 744-747

  Swaminathan, A ^a,c   Massasso, D ^a   Gotis Graham, I ^a   Gosbell, I ^b  

^a LIVERPOOL HOSPITAL   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c SWAPS   (Australia)

Author keywords

Deep vein thrombosis; Paediatric; Panton Valentine leucocidin; Staphylococcus aureus

Indexed keywords

ANTIBIOTIC AGENT; DICLOXACILLIN; FLUCLOXACILLIN; LEUKOCIDIN; PANTON VALENTINE LEUKOCIDIN; UNCLASSIFIED DRUG;

ADOLESCENT; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL ARTHRITIS; BACTERIAL GENE; BACTERIUM ISOLATE; BACTERIUM ISOLATION; BONE INFECTION; CASE REPORT; CLINICAL FEATURE; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HOUSEHOLD; HUMAN; IMMUNOCOMPETENCE; KNEE ARTHRITIS; METHICILLIN SENSITIVE STAPHYLOCOCCUS AUREUS; NONHUMAN; PANTON VALENTINE LEUCOCIDIN SYNDROME; PNEUMONIA; PRIORITY JOURNAL; SCREENING; SOFT TISSUE INFECTION; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION;

ADOLESCENT; ANTI-BACTERIAL AGENTS; ARTHRITIS, INFECTIOUS; BACTERIAL TOXINS; EXOTOXINS; HUMANS; IMMUNOCOMPETENCE; LEUKOCIDINS; MALE; METHICILLIN RESISTANCE; SEPSIS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 33749871145     PISSN: 14440903     EISSN: 14455994     Source Type: Journal    
DOI: 10.1111/j.1445-5994.2006.01220.x     Document Type: Article

References (17)

1. Lina G, Piemont Y, Godail-Gamot F, Bes M, Peter MO, Gauduchon V et al. Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia. Clin Infect Dis 1999; 29: 1128-32.
2. Tenover FC, Arbeit RD, Goering RV, Mickelsen PA, Murray BE, Persing DH et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995; 33: 2233-9.
3. Panton PN, Valentine FCO. Staphylococcal toxin. Lancet 1932; 1: 506-8.
4. Vandenesch F, Naimi T, Enright MC, Lina G, Nimmo GR, Heffernan H et al. Community-acquired methicillin-resistant Staphylococcus aureus carrying Panton-Valentine leukocidin genes: worldwide emergence. Emerg Infect Dis 2003; 9: 978-84.
5. Gosbell IB, Barbagiannakos T, Burke H, Kennedy C, Vickery A, Lambie P et al. Community MRSA in far western New South Wales, Australia: emergence of two epidemic clones and emergence of Panton-Valentine leukocidin in a previous Naïve clone. International Symposium on Staphylococci and Staphylococcal Infections; 2004 Oct 24-27; Charleston, SC, USA; 2004.
6. Gillet Y, Issartel B, Vanhems P, Fournet JC, Lina G, Bes M et al. Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients. Lancet 2002; 359: 753-9.
7. Zetola N, Francis JS, Nuermberger EL, Bishai WR. Community-acquired methicillin-resistant Staphylococcus aureus: an emerging threat. Lancet Infect Dis 2005; 5: 275-86.
8. Peleg AY, Munckhof WJ, Kleinschmidt SL, Stephens AJ, Huygens F. Life-threatening community-acquired methicillin-resistant Staphylococcus aureus infection in Australia. Eur J Clin Microbiol Infect Dis 2005; 24: 384-7.
9. Gonzalez BE, Martinez-Aguilar G, Hulten KG, Hammerman WA, Coss-Bu J, Avalos-Mishaan A et al. Severe Staphylococcal sepsis in adolescents in the era of community-acquired methicillin-resistant Staphylococcus aureus. Pediatrics 2005; 115: 642-8.
10. Martinez-Aguilar G, Avalos-Mishaan A, Hulten K, Hammerman W, Mason EO Jr, Kaplan SL. Community-acquired, methicillin-resistant and methicillin- susceptible Staphylococcus aureus musculoskeletal infections in children. Pediatr Infect Dis J 2004; 23: 701-6.
11. Sloniewsky D, Green TP. Pulmonary hemorrhage, embolism and infarction. In: Behrman RE, Kliegman RM, Hal BJ, eds. Nelson Book of Paediatrics, 17th edn. New York: WB Saunders; 2004; Ch 396, 1457-9.
12. Moreillon P, Que Y-A, Glauser MP. Staphylococcus aureus (including Staphylococcal toxic shock syndrome). In: Mandell GL, Bennett JE, Dolin R, eds. Mandell, Douglas and Bennett's Principles and Practice of Infectious Diseases. New York: Churchill Livingstone; 2005; 2321-51.
13. Boubaker K, Diebold P, Blanc DS, Vandenesch F, Praz G, Dupuis G et al. Panton-Valentine leukocidin and staphylococcal skin infections in schoolchildren. Emerg Infect Dis 2004; 10: 121-4.
14. Osterlund A, Kahlmeter G, Bieber L, Runehagen A, Breider JM. Intrafamilial spread of highly virulent Staphylococcus aureus strains carrying the gene for Panton-Valentine leukocidin. Scand J Infect Dis 2002; 34: 763-4.
15. Narita S, Kaneko J, Chiba J, Piemont Y, Jarraud S, Etienne J et al. Phage conversion of Panton-Valentine leukocidin in Staphylococcus aureus: molecular analysis of a PVL-converting phage, phiSLT. Gene 2001; 268: 195-206.
16. Mascini EM, Jansze M, Schouls LM, Verhoef J, Van Dijk H. Penicillin and clindamycin differentially inhibit the production of pyrogenic exotoxins A and B by group A streptococci. Int J Antimicrob Agents 2001; 18: 395-8.
17. van Langevelde P, van Dissel JT, Meurs CJ, Renz J, Groeneveld PH. Combination of flucloxacillin and gentamicin inhibits toxic shock syndrome toxin 1 production by Staphylococcus aureus in both logarithmic and stationary phases of growth. Antimicrob Agents Chemother 1997; 41: 1682-5.