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Volumn 13, Issue 11, 2006, Pages 1002-1010

Challenge with mammary tumor cells expressing MHC class II and CD80 prevents the development of spontaneously arising tumors in MMTV-neu transgenic mice

Author keywords

Breast cancer; CIITA; Costimulation; Immunity; MHC class II

Indexed keywords

B7 ANTIGEN; CLASS II TRANSACTIVATOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

EID: 33749861766     PISSN: 09291903     EISSN: 14765500     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700974     Document Type: Article
Times cited : (6)

References (49)
  • 1
    • 0028237348 scopus 로고
    • CD28-B7 interactions in T-cell activation
    • Allison JP. CD28-B7 interactions in T-cell activation. Curr Opin Immunol 1994; 6: 414-419.
    • (1994) Curr Opin Immunol , vol.6 , pp. 414-419
    • Allison, J.P.1
  • 2
    • 0036200757 scopus 로고    scopus 로고
    • CD28 function: A balance of co-stimulatory and regulatory signals
    • Bour-Jordan H, Blueston JA. CD28 function: a balance of co-stimulatory and regulatory signals. J Clin Immunol 2002; 22: 1-7.
    • (2002) J Clin Immunol , vol.22 , pp. 1-7
    • Bour-Jordan, H.1    Blueston, J.A.2
  • 3
    • 0036214017 scopus 로고    scopus 로고
    • The B7 family of ligands and its receptors: New pathways for co-stimulation and inhibition of immune responses
    • Carreno BM, Collins M. The B7 family of ligands and its receptors: new pathways for co-stimulation and inhibition of immune responses. Annu Rev Immunol 2002; 20: 29-53.
    • (2002) Annu Rev Immunol , vol.20 , pp. 29-53
    • Carreno, B.M.1    Collins, M.2
  • 4
    • 0242329384 scopus 로고    scopus 로고
    • Modulation of co-stimulation to enhance tumor immunity
    • Vesosky B, Hurwitz AA. Modulation of co-stimulation to enhance tumor immunity. Cancer Immunol Immunother 2003; 52: 663-669.
    • (2003) Cancer Immunol Immunother , vol.52 , pp. 663-669
    • Vesosky, B.1    Hurwitz, A.A.2
  • 5
    • 0027078670 scopus 로고
    • Co-stimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4
    • Chen L, Ashe S, Brady WA, Hellstrom I, Hellstrom KE, Ledbetter JA et al. Co-stimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4. Cell 1992; 71: 1093-1102.
    • (1992) Cell , vol.71 , pp. 1093-1102
    • Chen, L.1    Ashe, S.2    Brady, W.A.3    Hellstrom, I.4    Hellstrom, K.E.5    Ledbetter, J.A.6
  • 6
    • 0027982995 scopus 로고
    • Tumor immunogenicity determines the effect of B7 costimulation on T cell-mediated tumor immunity
    • Chen L, McGowan P, Ashe S, Johnston J, Li Y, Hellstrom I et al. Tumor immunogenicity determines the effect of B7 costimulation on T cell-mediated tumor immunity. J Exp Med 1994; 179: 523-532.
    • (1994) J Exp Med , vol.179 , pp. 523-532
    • Chen, L.1    McGowan, P.2    Ashe, S.3    Johnston, J.4    Li, Y.5    Hellstrom, I.6
  • 7
    • 0027946018 scopus 로고
    • B7-1/CD80-transduced tumor cells elicit better systemic immunity than wild-type tumor cells admixed with Corynebacterium parvum
    • Chen L, McGowan P, Ashe S, Johnston JV, Hellstrom I, Hellstrom KE. B7-1/CD80-transduced tumor cells elicit better systemic immunity than wild-type tumor cells admixed with Corynebacterium parvum. Cancer Res 1994; 54: 5420-5423.
    • (1994) Cancer Res , vol.54 , pp. 5420-5423
    • Chen, L.1    McGowan, P.2    Ashe, S.3    Johnston, J.V.4    Hellstrom, I.5    Hellstrom, K.E.6
  • 8
    • 0032418813 scopus 로고    scopus 로고
    • Anti-tumor immunity generated by tumor cells engineered to express B7-1 via retroviral or adenoviral gene transfer
    • Felzmann T, Ramsey WJ, Blaese RM. Anti-tumor immunity generated by tumor cells engineered to express B7-1 via retroviral or adenoviral gene transfer. Cancer Lett 1999; 135: 1-10.
    • (1999) Cancer Lett , vol.135 , pp. 1-10
    • Felzmann, T.1    Ramsey, W.J.2    Blaese, R.M.3
  • 9
    • 0032479141 scopus 로고    scopus 로고
    • Enhancement of the anti-tumor immune response using a combination of interferon-gamma and B7 expression in an experimental mammary carcinoma
    • Hurwitz AA, Townsend SE, Yu TF, Wallin JA, Allison JP. Enhancement of the anti-tumor immune response using a combination of interferon-gamma and B7 expression in an experimental mammary carcinoma. Int J Cancer 1998; 77: 107-113.
    • (1998) Int J Cancer , vol.77 , pp. 107-113
    • Hurwitz, A.A.1    Townsend, S.E.2    Yu, T.F.3    Wallin, J.A.4    Allison, J.P.5
  • 10
    • 0342632802 scopus 로고    scopus 로고
    • Vaccination with mouse mammary adenocarcinoma cells coexpressing B7-1 (CD80) and B7-2 (CD86) discloses the dominant effect of B7-1 in the induction of antitumor immunity
    • Martin-Fontecha A, Moro M, Crosti MC, Veglia F, Casorati G, Dellabona P. Vaccination with mouse mammary adenocarcinoma cells coexpressing B7-1 (CD80) and B7-2 (CD86) discloses the dominant effect of B7-1 in the induction of antitumor immunity. J Immunol 2000; 164: 698-704.
    • (2000) J Immunol , vol.164 , pp. 698-704
    • Martin-Fontecha, A.1    Moro, M.2    Crosti, M.C.3    Veglia, F.4    Casorati, G.5    Dellabona, P.6
  • 12
    • 0027392843 scopus 로고
    • Tumor rejection after direct costimulation of CD8+ T cells by B7-transfected melanoma cells
    • Townsend SE, Allison JP. Tumor rejection after direct costimulation of CD8+ T cells by B7-transfected melanoma cells. Science 1993; 259: 368-370.
    • (1993) Science , vol.259 , pp. 368-370
    • Townsend, S.E.1    Allison, J.P.2
  • 13
    • 0028646191 scopus 로고
    • Specificity and longevity of antitumor immune responses induced by B7-transfected tumors
    • Townsend SE, Su FW, Atherton JM, Allison JP. Specificity and longevity of antitumor immune responses induced by B7-transfected tumors. Cancer Res 1994; 54: 6477-6483.
    • (1994) Cancer Res , vol.54 , pp. 6477-6483
    • Townsend, S.E.1    Su, F.W.2    Atherton, J.M.3    Allison, J.P.4
  • 14
    • 0142093553 scopus 로고    scopus 로고
    • Immunization with a vaccine that combines the expression of MUC1 and B7 co-stimulatory molecules prolongs the survival of mice and delays the appearance of mouse mammary tumors
    • Vasilevko V, Ghochikyan A, Sadzikava N, Petrushina I, Tran M, Cohen EP et al. Immunization with a vaccine that combines the expression of MUC1 and B7 co-stimulatory molecules prolongs the survival of mice and delays the appearance of mouse mammary tumors. Clin Exp Metastasis 2003; 20: 489-498.
    • (2003) Clin Exp Metastasis , vol.20 , pp. 489-498
    • Vasilevko, V.1    Ghochikyan, A.2    Sadzikava, N.3    Petrushina, I.4    Tran, M.5    Cohen, E.P.6
  • 15
    • 0028934350 scopus 로고
    • Antitumor immunity elicited by tumor cells transfected with B7-2, a second ligand for CD28/CTLA-4 co-stimulatory molecules
    • Yang G, Hellstrom KE, Hellstrom I, Chen L. Antitumor immunity elicited by tumor cells transfected with B7-2, a second ligand for CD28/CTLA-4 co-stimulatory molecules. J Immunol 1995; 154: 2794-2800.
    • (1995) J Immunol , vol.154 , pp. 2794-2800
    • Yang, G.1    Hellstrom, K.E.2    Hellstrom, I.3    Chen, L.4
  • 16
    • 0142245326 scopus 로고    scopus 로고
    • Prevention of hepatocellular carcinoma in mice by IL-2 and B7-1 genes co-transfected liver cancer cell vaccines
    • Ge NL, Ye SL, Zheng N, Sun RX, Liu YK, Tang ZY. Prevention of hepatocellular carcinoma in mice by IL-2 and B7-1 genes co-transfected liver cancer cell vaccines. World J Gastroenterol 2003; 9: 2182-2185.
    • (2003) World J Gastroenterol , vol.9 , pp. 2182-2185
    • Ge, N.L.1    Ye, S.L.2    Zheng, N.3    Sun, R.X.4    Liu, Y.K.5    Tang, Z.Y.6
  • 17
    • 0033766179 scopus 로고    scopus 로고
    • Prostate cancer gene therapy: Comparison of adenovirus-mediated expression of interleukin 12 with interleukin 12 plus B7-1 for in situ gene therapy and gene-modified, cell-based vaccines
    • Hull GW, McCurdy MA, Nasu Y, Bangma CH, Yang G, Shimura S et al. Prostate cancer gene therapy: comparison of adenovirus-mediated expression of interleukin 12 with interleukin 12 plus B7-1 for in situ gene therapy and gene-modified, cell-based vaccines. Clin Cancer Res 2000; 6: 4101-4109.
    • (2000) Clin Cancer Res , vol.6 , pp. 4101-4109
    • Hull, G.W.1    McCurdy, M.A.2    Nasu, Y.3    Bangma, C.H.4    Yang, G.5    Shimura, S.6
  • 18
    • 0034868843 scopus 로고    scopus 로고
    • The immune anti-tumor effects of GM-CSF and B7-1 gene transfection are enhanced by surgical debulking of tumor
    • Mukherjee S, Nelson D, Loh S, van Bruggen J, Palmer LJ, Leong C et al. The immune anti-tumor effects of GM-CSF and B7-1 gene transfection are enhanced by surgical debulking of tumor. Cancer Gene Therapy 2001; 8: 580-588.
    • (2001) Cancer Gene Therapy , vol.8 , pp. 580-588
    • Mukherjee, S.1    Nelson, D.2    Loh, S.3    Van Bruggen, J.4    Palmer, L.J.5    Leong, C.6
  • 19
    • 0036193227 scopus 로고    scopus 로고
    • The experimental study of ovarian carcinoma vaccine modified by human B7-1 and IFN-gamma genes
    • Qian HN, Liu GZ, Cao SJ, Feng J, Ye X. The experimental study of ovarian carcinoma vaccine modified by human B7-1 and IFN-gamma genes. Int J Gynecol Cancer 2002; 12: 80-85.
    • (2002) Int J Gynecol Cancer , vol.12 , pp. 80-85
    • Qian, H.N.1    Liu, G.Z.2    Cao, S.J.3    Feng, J.4    Ye, X.5
  • 20
    • 0032765660 scopus 로고    scopus 로고
    • B7-1 (CD80)-gene transfer combined with interleukin-12 administration elicits protective and therapeutic immunity against mouse hepatocellular carcinoma
    • Tatsumi T, Takehara T, Kanto T, Kazushita H, Ito A, Kasahara A et al. B7-1 (CD80)-gene transfer combined with interleukin-12 administration elicits protective and therapeutic immunity against mouse hepatocellular carcinoma. Hepatology 1999; 30: 422-429.
    • (1999) Hepatology , vol.30 , pp. 422-429
    • Tatsumi, T.1    Takehara, T.2    Kanto, T.3    Kazushita, H.4    Ito, A.5    Kasahara, A.6
  • 21
    • 0037187017 scopus 로고    scopus 로고
    • Simultaneous expression of allogenic class II MHC and B7.1 (CD80) molecules in A20 B-lymphoma cell line enhances tumor immunogenicity
    • Jang YJ, Nam SY, Kim MS, Seong RH, Park YS, Chung YH et al. Simultaneous expression of allogenic class II MHC and B7.1 (CD80) molecules in A20 B-lymphoma cell line enhances tumor immunogenicity. Mol Cells 2002; 13: 130-136.
    • (2002) Mol Cells , vol.13 , pp. 130-136
    • Jang, Y.J.1    Nam, S.Y.2    Kim, M.S.3    Seong, R.H.4    Park, Y.S.5    Chung, Y.H.6
  • 22
    • 0032053794 scopus 로고    scopus 로고
    • Reduction of established spontaneous mammary carcinoma metastases following immunotherapy with major histocompatibility complex class II and B7.1 cell-based tumor vaccines
    • Pulaski BA, Ostrand-Rosenberg S. Reduction of established spontaneous mammary carcinoma metastases following immunotherapy with major histocompatibility complex class II and B7.1 cell-based tumor vaccines. Cancer Res 1998; 58: 1486-1493.
    • (1998) Cancer Res , vol.58 , pp. 1486-1493
    • Pulaski, B.A.1    Ostrand-Rosenberg, S.2
  • 24
    • 0036239887 scopus 로고    scopus 로고
    • Genetic control of MHC class II expression
    • Ting JP, Trowsdale J. Genetic control of MHC class II expression. Cell 2002; 109: S21-S33.
    • (2002) Cell , vol.109
    • Ting, J.P.1    Trowsdale, J.2
  • 25
    • 0034659727 scopus 로고    scopus 로고
    • Synergistic induction of HLA class I expression by RelA and CIITA
    • Girdlestone J. Synergistic induction of HLA class I expression by RelA and CIITA. Blood 2000; 95: 3804-3808.
    • (2000) Blood , vol.95 , pp. 3804-3808
    • Girdlestone, J.1
  • 26
    • 0033505297 scopus 로고    scopus 로고
    • Regulation of the expression of MHC class I and II by class II transactivator (CIITA) in hematopoietic cells
    • Liu A, Takahashi M, Toba K, Zheng Z, Hashimoto S, Nikkuni K et al. Regulation of the expression of MHC class I and II by class II transactivator (CIITA) in hematopoietic cells. Hematol Oncol 1999; 17: 149-160.
    • (1999) Hematol Oncol , vol.17 , pp. 149-160
    • Liu, A.1    Takahashi, M.2    Toba, K.3    Zheng, Z.4    Hashimoto, S.5    Nikkuni, K.6
  • 27
    • 0030982711 scopus 로고    scopus 로고
    • Induction of MHC class I expression by the MHC class II transactivator CIITA
    • Martin BK, Chin KC, Olsen JC, Skinner CA, Dey A, Ozato K et al. Induction of MHC class I expression by the MHC class II transactivator CIITA. Immunity 1997; 6: 591-600.
    • (1997) Immunity , vol.6 , pp. 591-600
    • Martin, B.K.1    Chin, K.C.2    Olsen, J.C.3    Skinner, C.A.4    Dey, A.5    Ozato, K.6
  • 28
    • 0033153498 scopus 로고    scopus 로고
    • Combination gene therapy with CD86 and the MHC class II transactivator in the control of lung tumor growth
    • Martin BK, Frelinger JG, Ting JP. Combination gene therapy with CD86 and the MHC class II transactivator in the control of lung tumor growth. J Immunol 1999; 162: 6663-6670.
    • (1999) J Immunol , vol.162 , pp. 6663-6670
    • Martin, B.K.1    Frelinger, J.G.2    Ting, J.P.3
  • 29
    • 0030921106 scopus 로고    scopus 로고
    • Major histocompatibility complex class II-transfected tumor cells present endogenous antigen and are potent inducers of tumor-specific immunity
    • Armstrong TD, Clements VK, Martin BK, Ting JP, Ostrand-Rosenberg S. Major histocompatibility complex class II-transfected tumor cells present endogenous antigen and are potent inducers of tumor-specific immunity. Proc Natl Acad Sci USA 1997; 94: 6886-6891.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 6886-6891
    • Armstrong, T.D.1    Clements, V.K.2    Martin, B.K.3    Ting, J.P.4    Ostrand-Rosenberg, S.5
  • 30
    • 0038297357 scopus 로고    scopus 로고
    • Tumor rejection by gene transfer of the MHC class II transactivator in murine mammary adenocarcinoma cells
    • Meazza R, Comes A, Orengo AM, Ferrini S, Accolla RS. Tumor rejection by gene transfer of the MHC class II transactivator in murine mammary adenocarcinoma cells. Eur J Immunol 2003; 33: 1183-1192.
    • (2003) Eur J Immunol , vol.33 , pp. 1183-1192
    • Meazza, R.1    Comes, A.2    Orengo, A.M.3    Ferrini, S.4    Accolla, R.S.5
  • 31
    • 0036626926 scopus 로고    scopus 로고
    • Epithelial and fibroblast cell lines derived from a spontaneous mammary carcinoma in a MMTV/neu transgenic mouse
    • Campbell MJ, Wollish WS, Lobo M, Esserman LJ. Epithelial and fibroblast cell lines derived from a spontaneous mammary carcinoma in a MMTV/neu transgenic mouse. In vitro Cell Dev Biol Anim 2002; 38: 326-333.
    • (2002) In Vitro Cell Dev Biol Anim , vol.38 , pp. 326-333
    • Campbell, M.J.1    Wollish, W.S.2    Lobo, M.3    Esserman, L.J.4
  • 32
    • 0025352187 scopus 로고
    • Advanced mammalian gene transfer: High titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
    • Morgenstern JP, Land H. Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res 1990; 18: 3587-3596.
    • (1990) Nucleic Acids Res , vol.18 , pp. 3587-3596
    • Morgenstern, J.P.1    Land, H.2
  • 33
    • 0027236954 scopus 로고
    • Production of high-titer helper-free retroviruses by transient transfection
    • Pear WS, Nolan GP, Scott ML, Baltimore D. Production of high-titer helper-free retroviruses by transient transfection. Proc Natl Acad Sci USA 1993; 90: 8392-8396.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8392-8396
    • Pear, W.S.1    Nolan, G.P.2    Scott, M.L.3    Baltimore, D.4
  • 34
    • 0026472124 scopus 로고
    • Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease
    • Guy CT, Webster MA, Schaller M, Parsons TJ, Cardiff RD, Muller WJ. Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease. Proc Natl Acad Sci USA 1992; 89: 10578-10582.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 10578-10582
    • Guy, C.T.1    Webster, M.A.2    Schaller, M.3    Parsons, T.J.4    Cardiff, R.D.5    Muller, W.J.6
  • 35
    • 0036318460 scopus 로고    scopus 로고
    • Major histocompatibility complex class II transcriptional platform: Assembly of nuclear factor Y and regulatory factor X (RFX) on DNA requires RFX5 dimers
    • Jabrane-Ferrat N, Nekrep N, Tosi G, Esserman LJ, Peterlin BM. Major histocompatibility complex class II transcriptional platform: assembly of nuclear factor Y and regulatory factor X (RFX) on DNA requires RFX5 dimers. Mol Cell Biol 2002; 22: 5616-5625.
    • (2002) Mol Cell Biol , vol.22 , pp. 5616-5625
    • Jabrane-Ferrat, N.1    Nekrep, N.2    Tosi, G.3    Esserman, L.J.4    Peterlin, B.M.5
  • 36
    • 0032965668 scopus 로고    scopus 로고
    • Enhancement by vasoactive intestinal peptide of gamma-interferon production by antigen-stimulated type 1 helper T cells
    • Jabrane-Ferrat N, Bloom D, Wu A, Li L, Lo D, Sreedharan SP et al. Enhancement by vasoactive intestinal peptide of gamma-interferon production by antigen-stimulated type 1 helper T cells. FASEB J 1999; 13: 347-353.
    • (1999) FASEB J , vol.13 , pp. 347-353
    • Jabrane-Ferrat, N.1    Bloom, D.2    Wu, A.3    Li, L.4    Lo, D.5    Sreedharan, S.P.6
  • 37
    • 0344211026 scopus 로고    scopus 로고
    • The optimal use of IRES (internal ribosome entry site) in expression vectors
    • Attal J, Theron MC, Houdebine LM. The optimal use of IRES (internal ribosome entry site) in expression vectors. Genet Anal 1999; 15: 161-165.
    • (1999) Genet Anal , vol.15 , pp. 161-165
    • Attal, J.1    Theron, M.C.2    Houdebine, L.M.3
  • 38
    • 0033331382 scopus 로고    scopus 로고
    • Effect of intercistronic length on internal ribosome entry site (IRES) efficiency in bicistronic mRNA
    • Attal J, Theron MC, Puissant C, Houdebine LM. Effect of intercistronic length on internal ribosome entry site (IRES) efficiency in bicistronic mRNA. Gene Expr 1999; 8: 299-309.
    • (1999) Gene Expr , vol.8 , pp. 299-309
    • Attal, J.1    Theron, M.C.2    Puissant, C.3    Houdebine, L.M.4
  • 39
    • 0141729438 scopus 로고    scopus 로고
    • Phosphorylation of class II transactivator regulates its interaction ability and transactivation function
    • Sisk TJ, Nickerson K, Kwok RP, Chang CH. Phosphorylation of class II transactivator regulates its interaction ability and transactivation function. Int Immunol 2003; 15: 1195-1205.
    • (2003) Int Immunol , vol.15 , pp. 1195-1205
    • Sisk, T.J.1    Nickerson, K.2    Kwok, R.P.3    Chang, C.H.4
  • 40
    • 0032524183 scopus 로고    scopus 로고
    • Kinase inhibitors abrogate IFN-gamma-induced class II transactivator and class II MHC gene expression in astroglioma cell lines
    • Van Wagoner NJ, O'Keefe GM, Benveniste EN. Kinase inhibitors abrogate IFN-gamma-induced class II transactivator and class II MHC gene expression in astroglioma cell lines. J Neuroimmunol 1998; 85: 174-185.
    • (1998) J Neuroimmunol , vol.85 , pp. 174-185
    • Van Wagoner, N.J.1    O'Keefe, G.M.2    Benveniste, E.N.3
  • 41
    • 0033048807 scopus 로고    scopus 로고
    • Generation of immunity to the HER-2/neu oncogenic protein in patients with breast and ovarian cancer using a peptide-based vaccine
    • Disis ML, Grabstein KH, Sleath PR, Cheever MA. Generation of immunity to the HER-2/neu oncogenic protein in patients with breast and ovarian cancer using a peptide-based vaccine. Clin Cancer Res 1999; 5: 1289-1297.
    • (1999) Clin Cancer Res , vol.5 , pp. 1289-1297
    • Disis, M.L.1    Grabstein, K.H.2    Sleath, P.R.3    Cheever, M.A.4
  • 43
    • 0038826485 scopus 로고    scopus 로고
    • Vaccination of women with metastatic breast cancer, using a co-stimulatory gene (CD80)-modified, HLA-A2-matched, allogeneic, breast cancer cell line: Clinical and immunological results
    • Dols A, Smith II JW, Meijer SL, Fox BA, Hu HM, Walker E et al. Vaccination of women with metastatic breast cancer, using a co-stimulatory gene (CD80)-modified, HLA-A2-matched, allogeneic, breast cancer cell line: clinical and immunological results. Hum Gene Ther 2003; 14: 1117-1123.
    • (2003) Hum Gene Ther , vol.14 , pp. 1117-1123
    • Dols, A.1    Smith II, J.W.2    Meijer, S.L.3    Fox, B.A.4    Hu, H.M.5    Walker, E.6
  • 44
    • 12144287913 scopus 로고    scopus 로고
    • A phase I vaccine safety and chemotherapy dose-finding trial of an allogeneic GM-CSF-secreting breast cancer vaccine given in a specifically timed sequence with immunomodulatory doses of cyclophosphamide and doxorubicin
    • Emens LA, Armstrong D, Biedrzycki B, Davidson N, Davis-Sproul J, Fetting J et al. A phase I vaccine safety and chemotherapy dose-finding trial of an allogeneic GM-CSF-secreting breast cancer vaccine given in a specifically timed sequence with immunomodulatory doses of cyclophosphamide and doxorubicin. Hum Gene Ther 2004; 15: 313-337.
    • (2004) Hum Gene Ther , vol.15 , pp. 313-337
    • Emens, L.A.1    Armstrong, D.2    Biedrzycki, B.3    Davidson, N.4    Davis-Sproul, J.5    Fetting, J.6
  • 45
    • 0033679535 scopus 로고    scopus 로고
    • Vaccination with a mixed vaccine of autogenous and allogeneic breast cancer cells and tumor associated antigens CA15-3, CEA and CA125 - Results in immune and clinical responses in breast cancer patients
    • Jiang XP, Yang DC, Elliott RL, Head JF. Vaccination with a mixed vaccine of autogenous and allogeneic breast cancer cells and tumor associated antigens CA15-3, CEA and CA125 - results in immune and clinical responses in breast cancer patients. Cancer Biother Radiopharm 2000; 15: 495-505.
    • (2000) Cancer Biother Radiopharm , vol.15 , pp. 495-505
    • Jiang, X.P.1    Yang, D.C.2    Elliott, R.L.3    Head, J.F.4
  • 46
    • 0036098003 scopus 로고    scopus 로고
    • Immunization of cancer patients with a HER-2/neu, HLA-A2 peptide, p369-377, results in short-lived peptide-specific immunity
    • Knutson KL, Schiffman K, Cheever MA, Disis ML. Immunization of cancer patients with a HER-2/neu, HLA-A2 peptide, p369-377, results in short-lived peptide-specific immunity. Clin Cancer Res 2002; 8: 1014-1018.
    • (2002) Clin Cancer Res , vol.8 , pp. 1014-1018
    • Knutson, K.L.1    Schiffman, K.2    Cheever, M.A.3    Disis, M.L.4
  • 47
    • 27144464759 scopus 로고    scopus 로고
    • Clinical trial results of a HER2/neu (E75) vaccine to prevent recurrence in high-risk breast cancer patients
    • Peoples GE, Gurney JM, Hueman MT, Woll MM, Ryan GB, Storrer CE et al. Clinical trial results of a HER2/neu (E75) vaccine to prevent recurrence in high-risk breast cancer patients. J Clin Oncol 2005; 23: 7536-7545.
    • (2005) J Clin Oncol , vol.23 , pp. 7536-7545
    • Peoples, G.E.1    Gurney, J.M.2    Hueman, M.T.3    Woll, M.M.4    Ryan, G.B.5    Storrer, C.E.6
  • 48
    • 0031785121 scopus 로고    scopus 로고
    • Immunization of metastatic breast cancer patients with CD80-modified breast cancer cells and GM-CSF
    • Schoof DD, Smith II JW, Disis ML, Brant-Zawadski P, Wood W, Doran T et al. Immunization of metastatic breast cancer patients with CD80-modified breast cancer cells and GM-CSF. Adv Exp Med Biol 1998; 451: 511-518.
    • (1998) Adv Exp Med Biol , vol.451 , pp. 511-518
    • Schoof, D.D.1    Smith II, J.W.2    Disis, M.L.3    Brant-Zawadski, P.4    Wood, W.5    Doran, T.6
  • 49
    • 0031649098 scopus 로고    scopus 로고
    • Ex-vivo gene therapy using cytokine-transduced tumor vaccines: Molecular and clinical pharmacology
    • Simons JW, Mikhak B. Ex-vivo gene therapy using cytokine-transduced tumor vaccines: molecular and clinical pharmacology. Semin Oncol 1998; 25: 661-676.
    • (1998) Semin Oncol , vol.25 , pp. 661-676
    • Simons, J.W.1    Mikhak, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.