Synthesis and characterization of suspension polymerized styrene-divinylbenzene porous microsphere using as slow-release-active carrier

Chinese Journal of Chemical Engineering

Volumn 14, Issue 4, 2006, Pages 471-477

  Li, Lu ^a   Cheng, Jiang ^a   Wen, Xiufang ^a   Pi, Pihui ^a   Yang, Zhuoru ^a  

^a SOUTH CHINA UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Porous microsphere; Slow release; Suspension polymerization; Ultrasonic dispersion

Indexed keywords

CHARACTERIZATION; DRUG PRODUCTS; MICROPOROUS MATERIALS; POLYMERIZATION; SCANNING ELECTRON MICROSCOPY; SOLVENT EXTRACTION; STYRENE; SUSPENSIONS (FLUIDS); ULTRASONIC DISPERSION;

POROUS MICROSPHERE; SLOW-RELEASE-ACTIVE CARRIER; STYRENE-DIVINYLBENZENE; SUSPENSION POLYMERIZATION;

CONTROLLED DRUG DELIVERY;

EID: 33749857243     PISSN: 10049541     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1004-9541(06)60101-8     Document Type: Article

References (17)

1. Unsal, E., Camli, S. T., Tuncel, A., Chromatographic performance of monodisperse-macroporous particles produced by modified seeded polymerization, Appl. Polym. Sci., 92(1), 607-618(2004).
2. Huang, F. C., Ke, C. H., Kao, C. Y., Li, W. C., Preparation and application of partially porous poly(styrene-divinylbenzene) particles for lipase immobilization, Appl. Polym. Sci., 80(1), 39-46(2001).
3. Zhang, S. H., Huang, X., Yao, N. S., Preparation of monodisperse porous polymethacrylate microspheres and their application in the capillary electrochromatography of macrolide antibiotics, J. Chromatogr. A., 948(2), 193-201 (2002).
4. Pan, J. Z., Zhang, L. J., Qian, Y., Structure property relationships and models of controlled drug delivery of biodegradable poly (d, l-lactic acid) microspheres, Chin. J. Chem. Eng., 12(6), 869-876(2004).
5. Lima, C. T., Coutinho, F. M. B., The influence of the diluent system on the porous structure formation of copolymers based on 2-vinylpyridine and divinylbenzene, Polym., 42(11), 4931-4938(2001).
6. Ugelstad, J., Nordhuus, I., Preparation and application of monodisperse polymer particles, J. Polym. Sci. Part A Polym. Chem., 72(2), 225-236(1985).
7. Omi, S., Katami, K., Yamamoto, A., Iso, M., Synthesis of monodisperse polymeric spheres employing glass membrance (SPG) emulsification technique and their applications, Macromolec. Symp., 92(4), 309-321(1995).
8. Amadeo, F., Muirel, B., Dominque, B., Optimization of a polymeric HPLC phase: Influence of the polymerization conditions on the pore structure of macroporous beads, React. Func. Polym., 56(2), 123-136(2003).
9. Cheng, Z., Werner, P., Moritz, H. U., Jan, P., Wamecke, H. J., A population balance model for disperse systems: Particle size distribution in suspension polymerization, Chin. J. Chem. Eng., 7(4), 332-344(1999).
10. Luiz, C., Alcino, A., Luciana, N., Microscopic analysis of porosity of 2-vinylpridine copolymer networks: Influence of diluent, Materials Letters, 58(5), 563-568(2004).
11. Xin, F., Wang, F. M., Liao, H., Li, S. F., Determination of a pore structure parameter of porous media by analysis of percolation network model, Chin. J. Chem. Eng., 8(4), 287-293(2000).
12. Okay, O., Macroporous copolymer networks, Progr. Polym. Sci., 25(6), 711-779(2000).
13. Luiz, C., Marcia, L., Marcos, C., Preparation of composite materials containing iron in a cross-linked resin host based on styrene and dibinybenzene, Europ. Polym. J., 39(4), 843-846(2003).
14. Okay, O., Phase separation in free-radical crosslinking copolymerization: Formation of hetergeneous polymer networks, Polym., 40(14), 4117-4129(1999).
15. Singh, B. S., Saxena, S. J., Beausoleil, M. H., Oil-in-water emulsion formation containing free and entrapped hydroquinone and retionol, U. S. Pat., 6896890 (2005).
16. Lee, Z. Z., Wen, L. X., Lei, S., Fabrication of porous hollow silica nanoparticles and their applications in drug release control, Controlled Release, 98(2), 245-254(2004).
17. Zhang, G. L., Shi, W., Zhang, F. B., Liu, Y., A mathematical model for diffusion-controlled monolithic matrix coated with outer membrane system, Chin. J. Chem. Eng., 9(1), 22-27(2001).