-
1
-
-
22844443043
-
Systemic therapy for metastatic colorectal cancer: Current options, current evidence
-
Kelly H, Goldberg RM. Systemic therapy for metastatic colorectal cancer: current options, current evidence. J Clin Oncol 2005;23:4553-4560.
-
(2005)
J Clin Oncol
, vol.23
, pp. 4553-4560
-
-
Kelly, H.1
Goldberg, R.M.2
-
2
-
-
2142703727
-
Survival of patients with advanced colorectal cancer improves with the availability of fluorouracil-leucovorin, irinotecan, and oxaliplatin in the course of treatment
-
Grothey A, Sargent D, Goldberg RM et al. Survival of patients with advanced colorectal cancer improves with the availability of fluorouracil-leucovorin, irinotecan, and oxaliplatin in the course of treatment. J Clin Oncol 2004;22:1209-1214.
-
(2004)
J Clin Oncol
, vol.22
, pp. 1209-1214
-
-
Grothey, A.1
Sargent, D.2
Goldberg, R.M.3
-
3
-
-
0034712536
-
Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: A multicentre randomised trial
-
Douillard JY, Cunningham D, Roth AD et al. Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial. Lancet 2000;355:1041-1047.
-
(2000)
Lancet
, vol.355
, pp. 1041-1047
-
-
Douillard, J.Y.1
Cunningham, D.2
Roth, A.D.3
-
4
-
-
0031019918
-
Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with bimonthly high-dose leucovorin and fluorouracil bolus plus continuous infusion for advanced colorectal cancer: A French intergroup study
-
de Gramont A, Bosset JF, Milan C et al. Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with bimonthly high-dose leucovorin and fluorouracil bolus plus continuous infusion for advanced colorectal cancer: a French intergroup study. J Clin Oncol 1997;15:808-815.
-
(1997)
J Clin Oncol
, vol.15
, pp. 808-815
-
-
De Gramont, A.1
Bosset, J.F.2
Milan, C.3
-
5
-
-
1842569206
-
A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer
-
Goldberg RM, Sargent DJ, Morton RF et al. A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 2004;22:23-30.
-
(2004)
J Clin Oncol
, vol.22
, pp. 23-30
-
-
Goldberg, R.M.1
Sargent, D.J.2
Morton, R.F.3
-
6
-
-
20644432867
-
Bevacizumab in combination with fluorouracil and leucovorin: An active regimen for first-line metastatic colorectal cancer
-
Hurwitz HI, Fehrenbacher L, Hainsworth JD et al. Bevacizumab in combination with fluorouracil and leucovorin: an active regimen for first-line metastatic colorectal cancer. J Clin Oncol 2005;23:3502-3508.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3502-3508
-
-
Hurwitz, H.I.1
Fehrenbacher, L.2
Hainsworth, J.D.3
-
7
-
-
20544471876
-
Combined analysis of efficacy: The addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer
-
Kabbinavar FF, Hambleton J, Mass RD et al. Combined analysis of efficacy: the addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer. J Clin Oncol 2005;23:3706-3712.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3706-3712
-
-
Kabbinavar, F.F.1
Hambleton, J.2
Mass, R.D.3
-
8
-
-
28244453575
-
Fluorouracil (FU), oxaliplatin (Ox), CPT-11 (irinotecan, Ir), use and sequencing, in advanced colorectal cancer (ACRC): The UK MRC FOCUS (CR08) trial
-
on behalf of the NCRI Colorectal Group
-
Maughan T, on behalf of the NCRI Colorectal Group. Fluorouracil (FU), oxaliplatin (Ox), CPT-11 (irinotecan, Ir), use and sequencing, in advanced colorectal cancer (ACRC): the UK MRC FOCUS (CR08) trial. 2005 Gastrointestinal Cancers Symposium:165a.
-
2005 Gastrointestinal Cancers Symposium
-
-
Maughan, T.1
-
9
-
-
27944501603
-
Fluorouracil, oxaliplatin and CPT-11 (irinotecan), use and sequencing (MRC FOCUS): A 2135-patient randomized trial in advanced colorectal cancer (ACRC)
-
for the UK NCRI Colorectal Clinical Studies Group
-
Seymour MT, for the UK NCRI Colorectal Clinical Studies Group. Fluorouracil, oxaliplatin and CPT-11 (irinotecan), use and sequencing (MRC FOCUS): a 2135-patient randomized trial in advanced colorectal cancer (ACRC). 2005 ASCO Annual Meeting3518a.
-
2005 ASCO Annual Meeting
-
-
Seymour, M.T.1
-
10
-
-
14644429819
-
5-Fluorouracil-based chemotherapy for advanced colorectal cancer in elderly patients: A North Central Cancer Treatment Group study
-
D'Andre S, Sargent DJ, Cha SS et al. 5-Fluorouracil-based chemotherapy for advanced colorectal cancer in elderly patients: a North Central Cancer Treatment Group study. Clin Colorectal Cancer 2005;4:325-331.
-
(2005)
Clin Colorectal Cancer
, vol.4
, pp. 325-331
-
-
D'Andre, S.1
Sargent, D.J.2
Cha, S.S.3
-
11
-
-
9744230871
-
OPTIMOX study: FOLFOX 7/LV5FU2 compared to FOLFOX 4 in patients with advanced colorectal cancer
-
ASCO Annual Meeting Proceedings (Post-Meeting Ed.)
-
De Gramont A, Cervantes A, Andre T et al. OPTIMOX study: FOLFOX 7/LV5FU2 compared to FOLFOX 4 in patients with advanced colorectal cancer. J Clin Oncol 2004 ASCO Annual Meeting Proceedings (Post-Meeting Ed.);22(14s)(suppl):3525.
-
(2004)
J Clin Oncol
, vol.22
, Issue.14 S SUPPL.
, pp. 3525
-
-
De Gramont, A.1
Cervantes, A.2
Andre, T.3
-
12
-
-
33749831024
-
5-Fluorouracil, folinic acid and oxaliplatin (FOLFOX) in poor prognosis patients with metastatic colorectal cancer
-
ASCO Annual Meeting Proceedings (Post-Meeting Ed.)
-
Tournigand C, Andre T, Chirivella I et al. 5-Fluorouracil, folinic acid and oxaliplatin (FOLFOX) in poor prognosis patients with metastatic colorectal cancer. J Clin Oncol 2004 ASCO Annual Meeting Proceedings (Post-Meeting Ed.);22(14s)(suppl):3565.
-
(2004)
J Clin Oncol
, vol.22
, Issue.14 S SUPPL.
, pp. 3565
-
-
Tournigand, C.1
Andre, T.2
Chirivella, I.3
-
13
-
-
0030756620
-
Modulation of 5-fluorouracil with folinic acid in advanced colorectal cancers
-
Groupe d'etude et de recherche sur les cancers de l'ovaire et digestifs (GERCOD)
-
de Gramont A, Louvet C, Andre T et al. [Modulation of 5-fluorouracil with folinic acid in advanced colorectal cancers. Groupe d'etude et de recherche sur les cancers de l'ovaire et digestifs (GERCOD)]. Rev Med Interne 1997;18(suppl 4):372s-378s.
-
(1997)
Rev Med Interne
, vol.18
, Issue.SUPPL. 4
-
-
De Gramont, A.1
Louvet, C.2
Andre, T.3
-
14
-
-
17744418861
-
Randomized phase III study of high-dose fluorouracil given as a weekly 24-hour infusion with or without leucovorin versus bolus fluorouracil plus leucovorin in advanced colorectal cancer: European Organization of Research and Treatment of Cancer Gastrointestinal Group Study 40952
-
Kohne CH, Wils J, Lorenz M et al. Randomized phase III study of high-dose fluorouracil given as a weekly 24-hour infusion with or without leucovorin versus bolus fluorouracil plus leucovorin in advanced colorectal cancer: European Organization of Research and Treatment of Cancer Gastrointestinal Group Study 40952. J Clin Oncol 2003;21:3721-3728.
-
(2003)
J Clin Oncol
, vol.21
, pp. 3721-3728
-
-
Kohne, C.H.1
Wils, J.2
Lorenz, M.3
-
15
-
-
0034798771
-
The evolution of fluoropyrimidine therapy: From intravenous to oral
-
Hoff PM, Cassidy J, Schmoll HJ et al. The evolution of fluoropyrimidine therapy: from intravenous to oral. The Oncologist 2001;6(suppl 4):3-11.
-
(2001)
The Oncologist
, vol.6
, Issue.SUPPL. 4
, pp. 3-11
-
-
Hoff, P.M.1
Cassidy, J.2
Schmoll, H.J.3
-
16
-
-
0035503151
-
Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: Results of a large phase III study
-
Van Cutsem E, Twelves C, Cassidy J et al. Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: results of a large phase III study. J Clin Oncol 2001;19:4097-4106.
-
(2001)
J Clin Oncol
, vol.19
, pp. 4097-4106
-
-
Van Cutsem, E.1
Twelves, C.2
Cassidy, J.3
-
17
-
-
0036895122
-
Early detection of toxicity and adjustment of ongoing clinical trials: The history and performance of the North Central Cancer Treatment Group's real-time toxicity monitoring program
-
Goldberg RM, Sargent DJ, Morton RF et al. Early detection of toxicity and adjustment of ongoing clinical trials: the history and performance of the North Central Cancer Treatment Group's real-time toxicity monitoring program. J Clin Oncol 2002;20:4591-4596.
-
(2002)
J Clin Oncol
, vol.20
, pp. 4591-4596
-
-
Goldberg, R.M.1
Sargent, D.J.2
Morton, R.F.3
-
18
-
-
7644244310
-
Mortality associated with daily bolus 5-fluorouracil/leucovorin administered in combination with either irinotecan or oxaliplatin: Results from Intergroup Trial N9741
-
Delaunoit T, Goldberg RM, Sargent DJ et al. Mortality associated with daily bolus 5-fluorouracil/leucovorin administered in combination with either irinotecan or oxaliplatin: results from Intergroup Trial N9741. Cancer 2004;101:2170-2176.
-
(2004)
Cancer
, vol.101
, pp. 2170-2176
-
-
Delaunoit, T.1
Goldberg, R.M.2
Sargent, D.J.3
-
19
-
-
33749840238
-
Update on capecitabine in colorectal cancer
-
Schmoll H-J, Arnold D. Update on capecitabine in colorectal cancer. The Oncologist 2006;11:1003-1009.
-
(2006)
The Oncologist
, vol.11
, pp. 1003-1009
-
-
Schmoll, H.-J.1
Arnold, D.2
-
20
-
-
14644438655
-
Evolution of FOLFOX regimens in the treatment of advanced colorectal cancer
-
Reddy GK, Gibson AD, Price N. Evolution of FOLFOX regimens in the treatment of advanced colorectal cancer. Clin Colorectal Cancer 2005;4:296-299.
-
(2005)
Clin Colorectal Cancer
, vol.4
, pp. 296-299
-
-
Reddy, G.K.1
Gibson, A.D.2
Price, N.3
-
21
-
-
0033874892
-
Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
-
de Gramont A, Figer A, Seymour M et al. Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol 2000;18:2938-2947.
-
(2000)
J Clin Oncol
, vol.18
, pp. 2938-2947
-
-
De Gramont, A.1
Figer, A.2
Seymour, M.3
-
22
-
-
1342290189
-
FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: A randomized GERCOR study
-
Tournigand C, Andre T, Achille E et al. FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J Clin Oncol 2004;22:229-237.
-
(2004)
J Clin Oncol
, vol.22
, pp. 229-237
-
-
Tournigand, C.1
Andre, T.2
Achille, E.3
-
23
-
-
24644457747
-
Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: A multicenter study of the Gruppo Oncologico Dell'Italia Meridionale
-
Colucci G, Gebbia V, Paoletti G et al. Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: a multicenter study of the Gruppo Oncologico Dell'Italia Meridionale. J Clin Oncol 2005;23:4866-4875.
-
(2005)
J Clin Oncol
, vol.23
, pp. 4866-4875
-
-
Colucci, G.1
Gebbia, V.2
Paoletti, G.3
-
24
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004;350:2335-2342.
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
25
-
-
7444224685
-
Integrating the anti-VEGF-A humanized monoclonal antibody bevacizumab with chemotherapy in advanced colorectal cancer
-
Hurwitz H. Integrating the anti-VEGF-A humanized monoclonal antibody bevacizumab with chemotherapy in advanced colorectal cancer. Clin Colorectal Cancer 2004;4(suppl 2):S62-S68.
-
(2004)
Clin Colorectal Cancer
, vol.4
, Issue.SUPPL. 2
-
-
Hurwitz, H.1
-
26
-
-
2942535898
-
Targeted therapy of colorectal cancer: Clinical experience with bevacizumab
-
Fernando NH, Hurwitz HI. Targeted therapy of colorectal cancer: clinical experience with bevacizumab. The Oncologist 2004;9(suppl 1):11-18.
-
(2004)
The Oncologist
, vol.9
, Issue.SUPPL. 1
, pp. 11-18
-
-
Fernando, N.H.1
Hurwitz, H.I.2
-
27
-
-
21844464600
-
Vatalanib (PTK787/ZK 222584) in combination with FOLFOX4 versus FOLFOX4 alone as first-line treatment for colorectal cancer: Preliminary results from the CONFIRM-1 trial
-
Tyagi P. Vatalanib (PTK787/ZK 222584) in combination with FOLFOX4 versus FOLFOX4 alone as first-line treatment for colorectal cancer: preliminary results from the CONFIRM-1 trial. Clin Colorectal Cancer 2005;5:24-26.
-
(2005)
Clin Colorectal Cancer
, vol.5
, pp. 24-26
-
-
Tyagi, P.1
-
28
-
-
21244481589
-
High-dose bevacizumab improves survival when combined with FOLFOX4 in previously treated advanced colorectal cancer: Results from the Eastern Cooperative Oncology Group (ECOG) study E3200
-
Giantonio BJ, Catalano PJ, Meropol NJ et al. High-dose bevacizumab improves survival when combined with FOLFOX4 in previously treated advanced colorectal cancer: results from the Eastern Cooperative Oncology Group (ECOG) study E3200. Proc Am Soc Clin Oncol 2005;24:2a.
-
(2005)
Proc Am Soc Clin Oncol
, vol.24
-
-
Giantonio, B.J.1
Catalano, P.J.2
Meropol, N.J.3
-
29
-
-
3242720345
-
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
-
Cunningham D, Humblet Y, Siena S et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 2004;351:337-345.
-
(2004)
N Engl J Med
, vol.351
, pp. 337-345
-
-
Cunningham, D.1
Humblet, Y.2
Siena, S.3
-
30
-
-
3242703033
-
New treatment options for colorectal cancer
-
Erlichman C, Sargent DJ. New treatment options for colorectal cancer. N Engl J Med 2004;351:391-392.
-
(2004)
N Engl J Med
, vol.351
, pp. 391-392
-
-
Erlichman, C.1
Sargent, D.J.2
-
31
-
-
21244475037
-
Interim report of randomized phase II trial of cetuximab/bevacizumab/ irinotecan (CBI) versus cetuximab/bevacizumab (CB) in irinotecan-refractory colorectal cancer
-
Abstract 169b
-
Saltz LB, Lenz H, Kindler H et al. Interim report of randomized phase II trial of cetuximab/bevacizumab/irinotecan (CBI) versus cetuximab/bevacizumab (CB) in irinotecan-refractory colorectal cancer. 2005 Gastrointestinal Cancer Symposium. Abstract 169b.
-
2005 Gastrointestinal Cancer Symposium
-
-
Saltz, L.B.1
Lenz, H.2
Kindler, H.3
-
32
-
-
21244475037
-
Randomized phase II trial of cetuximab/bevacizumab/irinotecan (CBI) versus cetuximab/bevacizumab (CB) in irinotecan-refractory colorectal cancer
-
Saltz LB, Lenz H, Hochster H et al. Randomized phase II trial of cetuximab/bevacizumab/irinotecan (CBI) versus cetuximab/bevacizumab (CB) in irinotecan-refractory colorectal cancer. Proc Am Soc Clin Oncol 2005;24:3508a.
-
(2005)
Proc Am Soc Clin Oncol
, vol.24
-
-
Saltz, L.B.1
Lenz, H.2
Hochster, H.3
-
33
-
-
23844548194
-
A randomized, double-blind, placebo-controlled, phase III study in patients (Pts) with metastatic adenocarcinoma of the colon or rectum receiving first-line chemotherapy with oxaliplatin/5-fluorouracil/leucovorin and PTK787/ZK 222584 or placebo (CONFIRM-1)
-
Hecht JR, Trarbach T, Jaeger E et al. A randomized, double-blind, placebo-controlled, phase III study in patients (Pts) with metastatic adenocarcinoma of the colon or rectum receiving first-line chemotherapy with oxaliplatin/5-fluorouracil/leucovorin and PTK787/ZK 222584 or placebo (CONFIRM-1). Proc Am Soc Clin Oncol 2005;24:3a.
-
(2005)
Proc Am Soc Clin Oncol
, vol.24
-
-
Hecht, J.R.1
Trarbach, T.2
Jaeger, E.3
-
34
-
-
6444243519
-
An international phase II study of cetuximab in combination with oxaliplatin/5-fluorouracil (5-FU)/folinic acid (FA) (FOLFOX-4) in the first-line treatment of patients with metastatic colorectal cancer (CRC) expressing epidermal growth factor receptor (EGFR). Preliminary results
-
ASCO Annual Meeting Proceedings (Post-Meeting Ed.)
-
Tabernero JM, Van Cutsem E, Sastre J et al. An international phase II study of cetuximab in combination with oxaliplatin/5-fluorouracil (5-FU)/folinic acid (FA) (FOLFOX-4) in the first-line treatment of patients with metastatic colorectal cancer (CRC) expressing epidermal growth factor receptor (EGFR). Preliminary results. J Clin Oncol 2004 ASCO Annual Meeting Proceedings (Post-Meeting Ed.);22(14S)(suppl):3512a.
-
(2004)
J Clin Oncol
, vol.22
, Issue.14 S SUPPL.
-
-
Tabernero, J.M.1
Van Cutsem, E.2
Sastre, J.3
-
35
-
-
6444230253
-
A phase II study of gefitinib in combination with FOLFOX-4 (IFOX) in patients with metastatic colorectal cancer
-
Fisher GA, Kuo T, Cho CD et al. A phase II study of gefitinib in combination with FOLFOX-4 (IFOX) in patients with metastatic colorectal cancer. 2004 ASCO Annual Meeting Proceedings (Post-Meeting Ed.);22 (14S)(suppl):3514a.
-
2004 ASCO Annual Meeting Proceedings (Post-Meeting Ed.)
, vol.22
, Issue.14 S SUPPL.
-
-
Fisher, G.A.1
Kuo, T.2
Cho, C.D.3
-
36
-
-
33749826383
-
First-line gefitinib combined with simplified FOLFOX-6 in patients with epidermal growth factor receptor-positive advanced colorectal cancer
-
Zampino MG, Lorizzo K, Massacesi C et al. First-line gefitinib combined with simplified FOLFOX-6 in patients with epidermal growth factor receptor-positive advanced colorectal cancer. 2004 ASCO Annual Meeting Proceedings (Post-Meeting Ed.);22(14S)(suppl):3659a.
-
2004 ASCO Annual Meeting Proceedings (Post-Meeting Ed.)
, vol.22
, Issue.14 S SUPPL.
-
-
Zampino, M.G.1
Lorizzo, K.2
Massacesi, C.3
|