Dextromethorphan premedication reduced postoperative analgesic consumption in patients after oral surgery

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology

Volumn 102, Issue 5, 2006, Pages 591-595

  Aoki, Takayuki ^a   Yamaguchi, Hiroshi ^b   Naito, Hiroyuki ^c   Shiiki, Kazuo ^c   Ota, Yoshihide ^d   Kaneko, Akihiro ^d  

^a TOKAI UNIVERSITY HACHIOJI HOSPITAL   (Japan)

^b Ryugasaki Saiseikai Hospital   (Japan)

^c Iwaki Kyoritsu Gen Hosp   (Japan)

^d TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DEXTROMETHORPHAN; DICLOFENAC; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NARCOTIC ANALGESIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT;

ADULT; ANALYSIS OF VARIANCE; AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG ANTAGONISM; FEMALE; HUMAN; MALE; MANDIBLE; MOLAR TOOTH; NONPARAMETRIC TEST; ORAL DRUG ADMINISTRATION; PAIN ASSESSMENT; POSTOPERATIVE PAIN; PREMEDICATION; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; TOOTH EXTRACTION;

ADMINISTRATION, ORAL; ADULT; ANALGESICS, OPIOID; ANALYSIS OF VARIANCE; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AREA UNDER CURVE; DEXTROMETHORPHAN; DICLOFENAC; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MANDIBLE; MOLAR, THIRD; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; PREMEDICATION; PROSPECTIVE STUDIES; RECEPTORS, N-METHYL-D-ASPARTATE; STATISTICS, NONPARAMETRIC; TOOTH EXTRACTION;

EID: 33749679461     PISSN: 10792104     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tripleo.2005.10.060     Document Type: Article

References (22)

1. Treede R.D., Meyer R.A., Raja S.N., and Campbell J.N. Peripheral and central mechanisms of cutaneous hyperalgesia. Prog Neurobiol 38 (1992) 397-421
2. Coderre T.J., Katz J., Vaccarino A.L., and Melzack R. Combination of central neuroplasticity to pathological pain: review of clinical and experimental evidence. Pain 52 (1993) 259-285
3. Woolf C.J., and Thompson S.W. The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation: implication for treatment of post injury pain hypersensitivity states. Pain 44 (1991) 293-300
4. Dray A. Inflammatory mediators of pain. Br J Anaesth 75 (1995) 125-131
5. Bennett G.J. Update on the neurophysiology of pain transmission and modulation: focus on the NM.D. A receptor. J Pain Symptom Manage 19 (2000) S2-S6
6. Mao J., Price D.D., and Mayer D.J. Mechanisms of hyperalgesia and morphine tolerance: a current view of their possible interactions. Pain 62 (1995) 259-274
7. Woolf C.J., and Chong M.S. Preemptive analgesia: treating postoperative pain by preventing the establishment of central sensitization. Anesth Analg 77 (1993) 362-379
8. Elliott K.J., Brodsky M., Hynansky A.D., Foley K.M., and Inturrisi C.E. Dextromethorphan suppresses both formalin-induced nociceptive behavior and the formalin-induced increase in spinal cord c-fos mRNA. Pain 61 (1995) 401-409
9. Dickenson A.H., and Sullivan A.F. Differential effects of excitatory amino-acid antagonists on dorsal horn nociceptive neurons in the rat. Brain Res 506 (1990) 31-39
10. Ilkjaer S., Dirks J., Brennum J., Wernberg M., and Dahl J.B. Effect of systemic N-methyl-D-aspartate receptor antagonist (dextromethorphan) on primary and secondary hyperalgesia in humans. Br J Anaesth 79 (1997) 600-605
11. Kawamata T., Omote K., Kawamata M., and Namiki A. Premedication with oral dextromethorphan reduces postoperative pain after tonsillectomy. Anesth Analg 86 (1998) 594-597
12. Helmy S.A., and Bali A. The effect of the preemptive use of the NM.D. A receptor antagonist dextromethorphan on postoperative analgesic requirements. Anesth Analg 92 (2001) 739-744
13. Liu S.T., Wu C.T., Yeh C.C., et al. Premedication with dextromethorphan provides posthemorrhoidectomy pain relief. Dis Colon Rectum 43 (2000) 507-510
14. Wu C.T., Yu J.C., Liu S.T., Yeh C.C., Li C.Y., and Wong C.S. Preincisional dextromethorphan treatment for postoperative pain management after upper abdominal surgery. World J Surg 24 (2000) 512-517
15. Chia Y.Y., Liu K., Chow L.H., and Lee T.Y. The preoperative administration of intravenous dextromethorphan reduces postoperative morphine consumption. Anesth Analg 89 (1999) 748-752
16. Wu C.T., Yu J.C., Yeh C.C., Liu S.T., Li C.Y., Ho S.T., et al. Preincisional dextromethorphan treatment decreases postoperative pain and opioid requirement after laparoscopic cholecystectomy. Anesth Analg 88 (1999) 1331-1334
17. Rose J.B., Cuy R., Cohen D.E., and Schreiner M.S. Preoperative oral dextromethorphan does not reduce pain or analgesic consumption in children after adenotonsillectomy. Anesth Analg 88 (1999) 749-753
18. Yeh C.C., Ho S.T., Kong S.S., Wu C.T., and Wong C.S. Absence of the preemptive analgesic effect of dextromethorphan in total knee replacement under epidural anesthesia. Acta Anaesthesiol Sin 38 (2000) 187-193
19. Gordon S.M., Dubner R., and Dionne R.A. Antihyperalgesic effect of the N-methyl-D-aspartate receptor antagonist dextromethorphan in the oral surgery model. J Clin Pharamcol 39 (1999) 139-146
20. Campbell W.I., Kendrick R.W., and Fee J.P. Balanced pre-emptive analgesia: does it work? A double-blind, controlled study in bilateral symmetrical oral surgery. Br J Anaesth 81 (1998) 727-730
21. Bridgman J.B., Gillgrass T.G., and Zacharias M. The absence of any pre-emptive analgesic effect for non-steroidial anti-inflammatory drugs. Br J Oral Maxillofac Surg 34 (1996) 428-431
22. Warner T.D., Giuliano F., Vojnovic I., Bukasa A., Mitchell J.A., and Vane J.R. Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proc Natl Acad Sci U S A 96 (1999) 7563-7568