Generation of simian-tropic HIV-1 by restriction factor evasion

Science

Volumn 314, Issue 5796, 2006, Pages 95-

  Hatziioannou, Theodora ^a   Princiotta, Michael ^b   Piatak Jr , Michael ^b   Yuan, Fang ^b   Zhang, Fengwen ^a   Lifson, Jeffrey D ^b   Bieniasz, Paul D ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b SAIC FREDERICK INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MACAQUE T CELLS; SIMIAN-TROPIC HIV-1;

CELL CULTURE; ENZYME KINETICS;

VIRUSES;

VIF PROTEIN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ENZYME; HUMAN IMMUNODEFICIENCY VIRUS; PRIMATE; RESEARCH;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS CAPSID; VIRUS GENOME; VIRUS INFECTIVITY; VIRUS REPLICATION;

ANIMALS; CAPSID PROTEINS; CELL LINE; CLONING, MOLECULAR; CYTOPATHOGENIC EFFECT, VIRAL; DISEASE MODELS, ANIMAL; GENES, VIF; HIV INFECTIONS; HIV-1; HUMANS; LYMPHOCYTES; MACACA MULATTA; RECOMBINATION, GENETIC; SIMIAN IMMUNODEFICIENCY VIRUS; T-LYMPHOCYTES; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1; PRIMATES; SIMIAE;

EID: 33749642641     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1130994     Document Type: Article

References (6)

1. P. D. Bieniasz, Nat. Immunol. 5, 1109 (2004).
2. M. Stremlau et al., Nature 427, 848 (2004).
3. A. M. Sheehy, N. C. Gaddis, J. D. Choi, M. H. Malim, Nature 418, 646 (2002).
4. R. Mariani et al., Cell 114, 21 (2003).
5. Materials and methods are available as supporting material on Science Online.
6. We thank V. KewalRamani, Z. Ambrose, D. Schneider, J. Smedley, and V. Coalter for advice and assistance and R. Desrosiers, J. Sodroski, and the NIH AIDS Reference Reagent Program for materials. Supported by the NIH, American Foundation for AIDS Research, and the Elizabeth Glaser Pediatric AIDS Foundation.