Synthesis and in vitro activity of a series 1β-methylcarbapenem derivatives

European Journal of Medicinal Chemistry

Volumn 41, Issue 10, 2006, Pages 1201-1209

  Jeon, H C ^b   Kim, J W ^a   Hong, J H ^c   Cho, J H ^a   Oh, C H ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Hanyang University   (South Korea)

^c Chosun University   (South Korea)

Author keywords

1 Methylcarbapenems; Antibacterial activity; Substituent effects

Indexed keywords

1BETA METHYLCARBAPENEM DERIVATIVE; 6 HYDROXYETHYL 2 [[5 (4 HYDROXYIMINO 3 ETHOXYCARBONYPYRROLIDINYL)CARBONYL] PYRROLIDIN 3 YLTHIO] 1 METHYLCARBAPEN 2 EM 3 CARBOXYLIC ACID; PIPERIDINE; PYRROLIDINE DERIVATIVE; UNCLASSIFIED DRUG; 1BETA METHYLCARBAPENEM; 1BETA-METHYLCARBAPENEM; ANTIINFECTIVE AGENT; CARBAPENEM DERIVATIVE;

ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; IN VITRO STUDY; NONHUMAN; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; MICROBIOLOGICAL EXAMINATION; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTI-BACTERIAL AGENTS; CARBAPENEMS; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33749627044     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2006.05.003     Document Type: Article

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